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Hi Installing crystallographic software shouldn't be a problem on an AMD Opteron. But if you have a choice, you might want to install a different OS than RedHate. SUSE & Ubuntu seem to be better choices at the moment. > We are trying to get a server with dual AMD Opteron 2200SE CPUs running > Redhat ES4 OS. Does anybody have experience on compiling > crystallographic programs such as ccp4, cns....on AMD powered machines? > Will it be a problem? Or we should stay with Intel Xeon servers? Harry -- Dr Harry Powell, MRC Laboratory of Molecular Biology, MRC Centre, Hills Road, Cambridge, CB2 2QH