Dear Clemens,

For the choice of derivatization compounds this might be helpfull:
Z. Dauter (2005). C. R. Chimie 8, 1808-1814.

Best Regards,
Georg



Clemens Grimm wrote:
Dear all,

after the SeMet phasing discussion, what would be -in general- the best technique to phase low resolution data (<=4A) of large complexes (>=150 kDA) - in terms of

- derivatization compounds (is there something like the 'golden five' HA compounds for these cases),

- data collection techniques and

- phasing methods?

Clemens


--
Universität Tübingen
Interfakultäres Institut für Biochemie
Dr. Georg Zocher
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