Hi All,
For a tutorial, we would like to demonstrate the method of ligand soaking in protein crystals. I am thinking about using some sort of native ligand or inhibitor that can be easily identified in the electron density rather than halide or heavy atom derivatization.
Does anybody have a suggestion for a protein/ligand combination that could be used for that and that is commercially available?
Thanks! Uli -- -------------------------------------------------------------------- Ulrich Zander High Troughput Crystallization Lab/Diffraction Instrumentation Team EMBL Grenoble Outstation 6 rue Jules Horowitz 38000 Grenoble, France Phone: +33 47620-9487 --------------------------------------------------------------------