Sucrose co-crystallized in lysozyme is wonderful. I think a soak will crack the crystals, but sometimes not.
Here's a pic of electron density from an orthorhombic crystal of lysozyme solved in the recent 2012 CSHL X-ray Methods in Structural Biology course: http://i46.tinypic.com/2e4xk7k.jpg Jim ________________________________________ From: CCP4 bulletin board [CCP4BB@JISCMAIL.AC.UK] on behalf of Ed Pozharski [epozh...@umaryland.edu] Sent: Friday, November 09, 2012 8:44 AM To: CCP4BB@JISCMAIL.AC.UK Subject: Re: [ccp4bb] model protein for ligand soaking On Fri, 2012-11-09 at 15:12 +0100, Ulrich Zander wrote: > Does anybody have a suggestion for a protein/ligand combination that > could be used for that and that is commercially available? Perhaps lysozyme complexed with some sugar? -- Bullseye! Excellent shot, Maurice. Julian, King of Lemurs.
