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Dear Uli,

the geometric ligands (I3C, B3C, B4C) by Tobias Beck
(http://www.protein.ethz.ch/people/tobias/) are both commercially
available and easily identified. I3C is suitable for inhouse data
collection and provide a strong anomalous signal.

Of course they are not 'native' but seem to suit your needs.

Cheers,
Tim

On 11/09/2012 03:12 PM, Ulrich Zander wrote:
> Hi All,
> 
> 
> For a tutorial, we would like to demonstrate the method of ligand 
> soaking in protein crystals. I am thinking about using some sort
> of native ligand or inhibitor that can be easily identified in the
> electron density rather than halide or heavy atom derivatization.
> 
> Does anybody have a suggestion for a protein/ligand combination
> that could be used for that and that is commercially available?
> 
> 
> Thanks!
> 
> Uli
> 
> 
> 
> 
> 
> 
> 
> 

- -- 
- --
Dr Tim Gruene
Institut fuer anorganische Chemie
Tammannstr. 4
D-37077 Goettingen

GPG Key ID = A46BEE1A

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