On Mon, Sep 20, 2010 at 9:26 AM, Stanley N Salthe <ssal...@binghamton.edu>wrote:
> Regarding the question: What is your > > opinion about Leroy E. Hood' words: "Biology Is an > Informational Science"? > > In a general sense the meaning is that, although every locale in the world > is mediated by history -- requiring information to be understand beyond > knowledge of physical and material laws -- biological systems have > internalized and replicate the results of historical accident as preserved > in the information in the genetic system. In general, history passes away, > but biological systems capture some of it in the form of species and variety > differences. > > STAN > > > On Mon, Sep 20, 2010 at 8:26 AM, Jorge Navarro López < > jnavarro.i...@aragon.es> wrote: > >> Dear Xueshan, >> >> Is the creation of Systems Biology related to Genomics, >> Proteomics, Transcriptomics, Glycomics, and many many other >> "-mics"? If so, what is the relationship between the Systems >> Biology and information from the x-mics angle? >> >> It is a very good question. In my practical experience, the "omic" >> disciplines provide a lot of data, usually compiled into data-bases, so that >> one can obtain many "lists of parts" about most processes and cellular >> subsystems. But in many cases that info is insufficient. For instance I am >> working in the signaling system of *Mycobacterium tuberculosis* and, if I >> go to the "tuberculist" data base, I can obtain more than two hundred >> transcriptional factors presumably related to signaling functions (belonging >> either to the "one, two or three-component systems"), however the true >> signaling function of each component is very difficult to obtain (a painful >> task one-by-one, searching at the literature). Thus I have to spent a lot of >> time to get a systemic or general approach, and even more if I want to >> build some models... >> Systems Biology is like ecology, that has to deal with the integration of >> a lot of partial specialized information from many other disciplines. >> >> What is your >> opinion about Leroy E. Hood' words: "Biology Is an >> Informational Science". >> >> >> I think (it is a very personal opinion!, obviously influenced by Pedro) >> that the leaders of Bioinformatic and Systems Biology (Gilbert, Hood, >> Brenner, Kitano, etc.) are not very serious in that type of statements. What >> they mean is that biology and molecular biology are becoming not really >> information sciences but intensive "computer science users". Usually one >> doesn´t find very deep theoretical reflexion in these guys although their >> works are very good from the technical point of view. >> >> >> Are there any difference between transmitter in Neuroscience >> and hormone in Endocrinology from the viewpoint of >> information transmission and communication ? >> >> >> >> Neurobiology is not my turf. Raquel will answer you very soon about >> that. >> >> By the way, do you know anyone working on Systems Biology in your >> University? >> >> Nice to talk to you! >> >> Jorge >> >> >> >> -- >> >> _______________________________________________ >> fis mailing list >> fis@listas.unizar.es >> https://webmail.unizar.es/cgi-bin/mailman/listinfo/fis >> >> >
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