> Dear Rudolph Pienaar,
> could you please tell me if the Folding index and the sulc are in a way
> correlated?
> thank you

Hi David -

This question does not really have a simple yes or no answer, mostly because 
each measures different features. These features are both derived from the 
topology of the surface, but are not directly related.

The 'sulc' measurement is the distance that a specific vertex is away from a 
hypothetical "mid-surface" that exists between the gyri and the sulci. This 
surface is chosen so that the "mean" of all the displacements is zero. The 
'sulc' gives a indication then of linear *distance* and displacements: how 
"deep" and how "high" are the folds, but doesn't say much about how "sharply" 
folded they are, or in what manner are they folded (like cylinders, like 
spheres, etc).

The FI is a *curvature* (not distance) measure. It uses the k1 and k2 
principal curvatures at each vertex to calculate a value according to (per Van 
Essen/Drury 1997):

        FI_i    = fabs(k1) * (fabs(k1) - fabs(k2));

Conceptually the FI tries to give a measure of how (relatively) tightly or 
sharply folded a gyrus is in a cylindrical sense. The more cylindrical a gyrus 
is, the more the FI increases along its length. For regions with spherical or 
saddle folding, k1 = k2 and the FI is zero. So it tells us more about how much 
like cylinders the folds are, but tell us nothing about how "deep" the folds 
extend.

Essentially, the 'sulc' and the FI are related of course by the topology of 
the surface but they each measure conceptually different things. It is not 
possible to determine 'sulc' from the FI or vice versa.

-- 
Rudolph Pienaar, M.Eng, D.Eng / email: [EMAIL PROTECTED]
MGH/MIT/HMS Athinoula A. Martinos Center for Biomedical Imaging
149 (2301) 13th Street, Charlestown, MA 02129 USA

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