Hi Bruce,

Thanks a lot for your reply.

> 2. The surface area of fsaverage is less than any individual, so you 
> *definitely* don't want to use it. You should map the ROI back to individuals 
> and compute it in the native space.

I have two follow-up questions: 


1) Do .pial.avg.area.mgh and/or .white.avg.area.mgh then store the mean native 
space surface areas for the individuals that were used to create fsaverage, and 
can I use these values to approximate the surface area of my ROIs then? 

2) Do the avg.area files also exists somewhere for the half-thickness 
mid-surface? If not, does it make sense to approximate the mid-thickness 
surface area at each vertex by taking the mean of the corresponding 
pial.avg.area and white.avg.area entries? 

Many thanks, 
Boris 


> 
> cheers
> Bruce
> 
> 
> On Wed, 11 May 2011, Boris Bernhardt wrote:
> 
>> Hello Freesurfer-experts,
>> 
>> I just analyzed some FreeSurfer cortical thickness data that have been 
>> surface-resampled to fsaverage (using mris_surf2surf with -s fsaverage).
>> 
>> For the visualization and reporting of my findings, I have a two questions:
>> 
>> 1. Is there anything that conceptually speaks against showing my results on 
>> non-inflated surfaces of fsaverage, such as the white matter surface, the 
>> pial surface, or even a mid-surface model?
>> 
>> 2. I have a couple of ROIs defined on the surface of fsaverage and want 
> to report the surface area of a given ROI in mm^2.  Should I calculate the 
> area of a ROI directly from the given surface of fsaverage, or to take the 
> area computations from ?h.pial.avg.area.mgh/?h.white.avg.area.mgh which 
> represent the averages of the individuals that went into fsaverage.
>> 
>> I am asking because I was slightly unclear of the wiki-instructions:
>> https://surfer.nmr.mgh.harvard.edu/fswiki/GroupAverageSurface
>> suggests to use ?h.pial.avg.area.mgh;
>> 
>> on the other hand, the more recently edited
>> http://surfer.nmr.mgh.harvard.edu/fswiki/FsAverage
>> says that "The surface area of the new average subject (fsaverage) is that 
>> of a typical subject"
>> 
>> I am using freesurfer 4.5.0.
>> 
>> Hope my questions make sense and thank you very much for answering them,
>> Boris
>> 
>> 
>> 
>> 
>> ---
>> Boris Bernhardt, PhD
>> Max Planck Institute for Human Cognitive and Brain Sciences
>> Stephanstr. 1a, 04103 Leipzig, Germany
>> 
>> p: +(49) 341 9940 2658
>> e: bernha...@cbs.mpg.de
>> http://www.cbs.mpg.de/~bernhardt
>> 
>> 
> 
> 
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---
Boris Bernhardt
Max Planck Institute for Human Cognitive and Brain Sciences 
Stephanstr. 1a, 04103 Leipzig, Germany 

p: +(49) 341 9940 2658  
e: bernha...@cbs.mpg.de
http://www.cbs.mpg.de/~bernhardt





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