It is okay to study a single cohort with covariates.
doug

On 06/14/2012 11:54 AM, Dhinakaran Chinappen wrote:
> Dear Freesurfer Experts,
>
> For one of our studies, I have used QDEC to analyze the relationship 
> between cortical thickness and a series of variables.
>
> I wanted to double check to see if it is okie to have a qdec table 
> which only includes the diseased population and the covariates (such 
> as FSIQ).
>
> After multiple comparison correction, a few clusters were obtained, 
> where the correlation between thickness and the covariate differs from 
> zero.
>
> Please let me know if QDEC should only be used for comparison between 
> groups or if it okie to study only one cohort and subsequently analyze 
> the trend of a variable with cortical thickness.
>
> Best,
> Dhinakaran.
>
>
>
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-- 
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
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