In my data-set I have observed that Freesurfer has a tendency to include
some amygdala into the hippocampal head, despite a visible strip of alveus
white-matter segregating hippocampus from amygdala in my images. Has this
tendency been noticed by others? If so, has anyone found a non-manual
correction?
Best,
-
Josh

On Thu, Aug 2, 2012 at 7:37 AM, Bruce Fischl <fis...@nmr.mgh.harvard.edu>wrote:

> Hi Fred
>
> 1. Yes, this has been done multiple times, including in our original 2002
> paper:
> https://surfer.nmr.mgh.**harvard.edu/ftp/articles/**fischl02-labeling.pdf<https://surfer.nmr.mgh.harvard.edu/ftp/articles/fischl02-labeling.pdf>
>
> 2. You can manually edit, but it's a lot more work. In the cortex minor
> interventions can lead to large improvements in accuracy. Unfortunately we
> have no such algorithm subcortically. That said, things are usually quite
> accurate except in a small percentage of cases.
>
> cheers
> Bruce
>
>
>
> On Wed, 1 Aug 2012, Fred Sanders wrote:
>
>  Hi All,
>> Two questions:
>>
>> 1. I am interested in subcortical gray matter volumes such as hippocampus,
>> amygdala, & basal ganglia. Can someone recommend some good references
>> looking at the accuracy of Freesurfer relative to the "gold standard"
>> approach of hand-tracing these structures?
>>
>> 2. Most of the problems that require quality checks for Freesurfer relate
>> to
>> defining the cortical surface and the grey-white boundary.  As far as I
>> can
>> tell, there is rarely a need to edit Freesurfer's definitions of
>> subcortical
>> gray.  Am I correct in this?
>>
>>
>>
>> Thanks!
>> Fred
>>
>>
>>
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