yes
doug
On 05/31/2013 12:16 PM, Fotiadis, Panagiotis wrote:
> Hey Doug,
>
> Great, but besides the unbalanced numbers in each cohort, the fact that we 
> have a cross sectional analysis instead of a longitudinal one doesn't matter 
> right? Would it be correct to say that we still apply the same group analysis 
> described in the wiki?
>
> Thanks,
> Panos
> ________________________________________
> From: freesurfer-boun...@nmr.mgh.harvard.edu 
> [freesurfer-boun...@nmr.mgh.harvard.edu] on behalf of Douglas N Greve 
> [gr...@nmr.mgh.harvard.edu]
> Sent: Friday, May 31, 2013 11:59 AM
> To: freesurfer@nmr.mgh.harvard.edu
> Subject: Re: [Freesurfer] Group Analysis
>
> Hi Panos, are you asking whether theunbalanced design will leadto one
> slope being different than another just because the numbers are
> different? That is not a problem. You can simply follow the instructions
> on the wiki.
> doug
>
>
>
> On 05/31/2013 11:26 AM, Fotiadis, Panagiotis wrote:
>> Hey Doug,
>>
>> Sorry for the overwhelming amount of questions. I wanted to confirm 
>> something. Suppose you want to do group analysis between two groups say a 
>> healthy cohort vs a diseased cohort. Each cohort has ~40 and ~30 subjects 
>> each (different people), and you want to compare how for instance the 
>> cortical thickness decreases over age in the one group versus the other. Do 
>> you still set the contrast vector as [0 0 1 -1]  ([intercept 1 intercept 2 
>> slope 1 slope 2]) and follow the analysis described in 
>> https://surfer.nmr.mgh.harvard.edu/fswiki/FsTutorial/GroupAnalysis or do you 
>> go on a different way since there are different subjects instead of one with 
>> 40 (or 30) different longitudinal data for each cohort? Don't we need to 
>> correct the age slopes for the fact that we have 40 (and 30) different 
>> subjects in each cohort?
>>
>> Thanks,
>> Panos
>> _______________________________________________
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>> Freesurfer@nmr.mgh.harvard.edu
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>>
>>
> --
> Douglas N. Greve, Ph.D.
> MGH-NMR Center
> gr...@nmr.mgh.harvard.edu
> Phone Number: 617-724-2358
> Fax: 617-726-7422
>
> Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
> FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2
> www.nmr.mgh.harvard.edu/facility/filedrop/index.html
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>
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>

-- 
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
Phone Number: 617-724-2358
Fax: 617-726-7422

Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2
www.nmr.mgh.harvard.edu/facility/filedrop/index.html
Outgoing: ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/

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