So the T2-SPACE is a variable flip angle sequence that actually has a fair
amount of T1 and MT contrast in it and relatively less T2 contrast.  As a
result, you can clearly see the difference between grey and white matter,
and CSF is not massively brighter than grey and white matter.  If you are
using a different kind of T2w sequence where the distance between CSF
intensity and grey matter intensity is much greater, some of the internal
settings to the -T2pial flag will likely not be optimal.  I don't know if
recon-all allows you to modify those with expert options or not.  Bruce, is
it possible for the user to modify the ­nsigma_above and -nsigma_below flags
for mris_make_surfaces when using -T2pial?

Peace,

Matt.

From:  Michael Waskom <mwas...@stanford.edu>
Date:  Friday, September 27, 2013 2:20 PM
To:  Matt Glasser <m...@ma-tea.com>
Cc:  Bruce Fischl <fis...@nmr.mgh.harvard.edu>,
"Freesurfer@nmr.mgh.harvard.edu" <Freesurfer@nmr.mgh.harvard.edu>
Subject:  Re: [Freesurfer] Major problems with T2-based pial removal

Hi Matt,

It's this sequence:
http://cni.stanford.edu/wiki/MR_Protocols#T2_weighted_scans (the 3D T2)

You can click the console screenshots for a closer view of the parameters --
let me know if you need me to track down more info.

mw


On Fri, Sep 27, 2013 at 11:38 AM, Matt Glasser <m...@ma-tea.com> wrote:
> Someone sent me a different kind of T2w image and it didn't work so well,
> so we need to know what kind of image this is.
> 
> Peace,
> 
> Matt.
> 
> On 9/27/13 1:33 PM, "Bruce Fischl" <fis...@nmr.mgh.harvard.edu> wrote:
> 
>> >nope, pretty much only with T2-space with and without a flair pulse
>> >On Fri,
>> >27 Sep 2013, Matt Glasser wrote:
>> >
>>> >> Also, what kind of T2w sequence is this?  I think we've mostly tested it
>>> >> with the T2-SPACE (unless Bruce has tested with other things).
>>> >>
>>> >> Peace,
>>> >>
>>> >> Matt.
>>> >>
>>> >> On 9/27/13 12:58 PM, "Bruce Fischl" <fis...@nmr.mgh.harvard.edu> wrote:
>>> >>
>>>> >>> Hi Michael
>>>> >>>
>>>> >>> that looks pretty bad! What is the resolution of the T2? The T1 that
>>>> >>>you
>>>> >>> overlay on also looks somewhat blurry - what was it?
>>>> >>>
>>>> >>> Bruce
>>>> >>>
>>>> >>>
>>>> >>> On Fri, 27 Sep
>>>> >>> 2013, Michael Waskom wrote:
>>>> >>>
>>>>> >>>> Hi, just to make the problem a bit more transparent, I took a second
>>>>> >>>> screenshot of the slices with the pial surface from the -T2pial run
in
>>>>> >>>> red
>>>>> >>>> and the pial surface from the normal run in
>>>>> >>>> cyan: 
>>>>> https://dl.dropbox.com/s/jv8rcxnq50tdac6/bad_slice_both_pial.png
>>>>> >>>>
>>>>> >>>> On Fri, Sep 27, 2013 at 10:37 AM, Michael Waskom
>>>>> >>>><mwas...@stanford.edu>
>>>>> >>>> wrote:
>>>>> >>>>       Hi,
>>>>> >>>> I'm using FS 5.3 and trying to use hires T2-weighted scans to refine
>>>>> >>>> the pial mesh.
>>>>> >>>>
>>>>> >>>> However, I've found that using the T2 is causing rather dramatic
>>>>> >>>> problems with the pial surface.
>>>>> >>>>
>>>>> >>>> I processed the same subject's data with and without the -T2pial
>>>>> >>>> option. Here are links to a) pial surface image b) slices through the
>>>>> >>>> volume and c) the recon-all.log:
>>>>> >>>>
>>>>> >>>> With -T2pial
>>>>> >>>> ----------------
>>>>> >>>> https://dl.dropbox.com/s/rtjgplajfptr4xb/bad_surf_withT2.png
>>>>> >>>> https://dl.dropbox.com/s/d7so5qtujgg8j80/bad_slice_withT2.png
>>>>> >>>> https://dl.dropbox.com/s/7o00jy014hihrgu/recon_log_withT2.txt
>>>>> >>>>
>>>>> >>>> Without -T2pial
>>>>> >>>> --------------------
>>>>> >>>> https://dl.dropbox.com/s/51y15kogecltfbi/bad_surf_noT2.png
>>>>> >>>> https://dl.dropbox.com/s/3gps45kp0ngkuli/bad_slice_noT2.png
>>>>> >>>> https://dl.dropbox.com/s/6jih6f8fh4nwh0k/recon_log_noT2.txt
>>>>> >>>>
>>>>> >>>> The release notes for 5.3 claim that the T2 is registered to the T1
>>>>> >>>> before refining the surface, but I actually can't find any evidence
of
>>>>> >>>> that sequence in the log file. For this subject, the T1 and T2 came
>>>>> >>>> from different scan sessions, although I have other data where they
>>>>> >>>> were acquired in the same session that have similar, if less
>>>>> dramatic,
>>>>> >>>> problems with the pial surface.
>>>>> >>>>
>>>>> >>>> Any ideas?
>>>>> >>>>
>>>>> >>>> Michael
>>>>> >>>>
>>>>> >>>>
>>>>> >>>>
>>>>> >>>> _______________________________________________
>>>> >>> Freesurfer mailing list
>>>> >>> Freesurfer@nmr.mgh.harvard.edu
>>>> >>> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
>>>> >>>
>>>> >>>
>>>> >>> The information in this e-mail is intended only for the person to whom
>>>> >>>it
>>>> >>> is
>>>> >>> addressed. If you believe this e-mail was sent to you in error and the
>>>> >>> e-mail
>>>> >>> contains patient information, please contact the Partners Compliance
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>>>> >>> but does not contain patient information, please contact the sender and
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>>> >>
>>> >>
>>> >>
>>> >>
> 
> 



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