Great, thanks for the clarification Doug!

Best,
Alex

>
> It depends on how are you defining "percent contrast". What you are are
> slightly different methods.
>
> Using -m cespct is equivalent to computing
> 100*Sum(contrast_i/baseline_i)/N where i is a voxel in the ROI
> Your method is equivalent to computing 100*Sum(contrast_i)/Sum(baseline_i)
>
> So they will be close but not exact. Which one is better? Hard to say. I
> would tend toward -m cespect
>
> doug
>
>
>
> On 11/01/2013 01:43 PM, Alexandra Tanner wrote:
>> Hi Doug,
>>
>> Thanks, this seems to work!
>>
>> Quick question -- in the past we've done ROI analyses where we've
>> functionally constrained our labels. When calculating percent signal
>> change we would take the output from funcroi-table-sess divide it by the
>> output of funcroi-table-sess with no -c flag (the baseline offset value)
>> and multiply by 100. Is this also a correct method for calculating
>> percent
>> signal change? I've tried it for the current ROI I'm using and compared
>> my
>> calculated value to the value I got by adding -m cespct and the numbers
>> I'm getting are not the same (ex. 0.0159 vs 0.01444 for one subject). Is
>> -m cespct more accurate? Thanks!
>>
>> Best,
>> Alex
>>
>>
>>> Hi Alex, if you use "-m cespct" it will report the mean percent signal
>>> change within the ROI. Does this work?
>>> doug
>>>
>>>
>>> On 10/31/2013 02:37 PM, Alexandra Tanner wrote:
>>>> Hi Doug and Freesurfers,
>>>>
>>>> I would like to calculate percent signal change within an anatomical
>>>> ROI
>>>> for a group of subjects in Freesurfer 5.0. We are not functionally
>>>> constraining our ROI, however, we do want to calculate the percent
>>>> signal
>>>> change across the entire region in each of our conditions (the
>>>> contrasts
>>>> we are using are condition-vs-fixation). Below are examples of the
>>>> commands I've run for one of our conditions:
>>>>
>>>> funcroi-config -analysis SIRP_Stable5 -label lh.7Network_6.PFC.label
>>>> -roi
>>>> /cluster/roffman/users/Stable5_PerRun/ROI_Analysis/FB12/Anatomical_roicfg_103113/SIRP_lh_7Networks_6_PFC.roicfg
>>>>
>>>> funcroi-sess -roi
>>>> /cluster/roffman/users/Stable5_PerRun/ROI_Analysis/FB12/Anatomical_roicfg_103113/SIRP_lh_7Networks_6_PFC.roicfg
>>>> -sf
>>>> /cluster/roffman/users/Stable5_PerRun/Subject_Files/30_ActiveFolateAndPlacebo_PostPrePAIRED
>>>>
>>>> funcroi-table-sess -roi
>>>> /cluster/roffman/users/Stable5_PerRun/ROI_Analysis/FB12/Anatomical_roicfg_103113/SIRP_lh_7Networks_6_PFC.roicfg
>>>> -sf
>>>> /cluster/roffman/users/Stable5_PerRun/Subject_Files/30_ActiveFolateAndPlacebo_PostPrePAIRED
>>>> -o
>>>> /cluster/roffman/users/Stable5_PerRun/ROI_Analysis/FB12/Anatomical_roicfg_103113/18ActiveFolate_12Placebo_PreAndPost_7Tpost/lh_7Networks_6_PFC_1vFix
>>>> -c Cond1vFix
>>>>
>>>> Is it necessary to now generate the mean functional baseline offset
>>>> value
>>>> within the ROI in order to calculate percent signal change if our
>>>> contrast
>>>> is comparing condition-vs-fixation? Any clarification on when the
>>>> offset
>>>> value is needed would be greatly appreciated!
>>>>
>>>> Thanks,
>>>> Alex
>>>>
>>>>
>>>>
>>>>
>>> --
>>> Douglas N. Greve, Ph.D.
>>> MGH-NMR Center
>>> gr...@nmr.mgh.harvard.edu
>>> Phone Number: 617-724-2358
>>> Fax: 617-726-7422
>>>
>>> Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
>>> FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2
>>> www.nmr.mgh.harvard.edu/facility/filedrop/index.html
>>> Outgoing:
>>> ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/
>>>
>>>
>>>
>>
>
> --
> Douglas N. Greve, Ph.D.
> MGH-NMR Center
> gr...@nmr.mgh.harvard.edu
> Phone Number: 617-724-2358
> Fax: 617-726-7422
>
> Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
> FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2
> www.nmr.mgh.harvard.edu/facility/filedrop/index.html
> Outgoing: ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/
>
>
>

_______________________________________________
Freesurfer mailing list
Freesurfer@nmr.mgh.harvard.edu
https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer


The information in this e-mail is intended only for the person to whom it is
addressed. If you believe this e-mail was sent to you in error and the e-mail
contains patient information, please contact the Partners Compliance HelpLine at
http://www.partners.org/complianceline . If the e-mail was sent to you in error
but does not contain patient information, please contact the sender and properly
dispose of the e-mail.

Reply via email to