> Hello,
>
>
> Is there any detailed information on the possible differences in results
> wwhen upgrading to the latest FreeSurfer software?
>
> As it pertains to the scans already processed with old software compared
> to
> any scans processed with a newer version of the software.

When freesurfer6.0 is released we will publish a set of brain maps for
some of our internal data sets which will show the regions of the brain
that demonstrate statistical differences for various measures (e.g.
thickness, area) between the most recent release v5.3 and the upcoming
release v6.0. Whether your data will exhibit the same trends is impossible
to say. But we do make the following statement on our download page in
regards to processing subjects with freesurfer:


"
*Important Note!* When processing a group of subjects for your study, it
is essential to process all your subjects with the same version of
freesurfer, on the same OS platform and vendor, and for safety, even the
same version of the OS. While we continue to work to ensure that results
match across platforms (for instance the 32b and 64b CentOS 4 builds
should produce identical results), there are none-the-less system-level
libraries that are OS dependent. An exception to this rule is that you may
view and edit files across any platform or version, and run some
post-processing tools (outside the recon-all stream) if you check with us
first (for instance you may run the longitudinal processing with newer
versions).
"

>
> Can I install the new version of Freeview without the new version of
> FreeSurfer? Would there be any differences to between scans corrected
> before and after upgrade?

Yes, you can install the new version of freeview over your existing
version of freeview as updates to that application, and edits made with
it, should not effect to overall processing stream. Just follow the
"Freeview dev version" download instructions on this page:

https://surfer.nmr.mgh.harvard.edu/fswiki/Download

> I cannot seem to get the 'curl -O' to download the software. Are there any
> troubleshooting methods to this? Testing the harvard ftp server also
> fails.
> Has it been down?

I just tested the following commands on my home network and they both
worked for me.

$> curl -O
ftp://surfer.nmr.mgh.harvard.edu/pub/dist/freesurfer/5.3.0/freesurfer-Darwin-lion-stable-pub-v5.3.0.dmg

$> curl -O
ftp://surfer.nmr.mgh.harvard.edu/pub/dist/freesurfer/freeview/lion/Freeview.zip


-Zeke

>
> Thank you so much,
>
> Joseph
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> Freesurfer@nmr.mgh.harvard.edu
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