Dear Douglas,

My command lines were, e.g. right thickness and right white surface (using
the same ad_hv.fsgd and group_diff.mtx files in the command lines):


ad_hv.fsgd

GroupDescriptorFile 1
Title AD_HV_GroupAnalysis
Class AD
Class HV
Input AD_003 AD
Input AD_005 AD
...
Input HV_AB HV
Input HV_AE HV


group_diff.mtx

1 -1


right thickness

mris_preproc --fsgd ad_hv.fsgd --cache-in thickness.fwhm10.fsaverage
--target fsaverage --hemi rh --out rh.ad_hv.thick.10.mgh

mri_glmfit --y rh.ad_hv.thick.10.mgh --fsgd ad_hv.fsgd dods --C
group_diff.mtx --surf fsaverage rh --cortex --glmdir rh.ad_hv.thick.glmdir

mri_glmfit-sim --glmdir rh.ad_hv.thick.glmdir --cache 4 neg --cwp 0.05
--2spaces


right white surface

mris_preproc --fsgd ad_hv.fsgd --cache-in area.fwhm10.fsaverage --target
fsaverage --hemi rh --out rh.ad_hv.area.10.mgh

mri_glmfit --y rh.ad_hv.area.10.mgh --fsgd ad_hv.fsgd dods --C
group_diff.mtx --surf fsaverage rh --cortex --glmdir rh.ad_hv.area.glmdir

mri_glmfit-sim --glmdir rh.ad_hv.area.glmdir --cache 4 neg --cwp 0.05
--2spaces


Their results were all the same.

Thanks,
Kaiming


---------- Forwarded message ----------
From: Douglas N Greve <gr...@nmr.mgh.harvard.edu>
To: freesurfer@nmr.mgh.harvard.edu
Cc:
Date: Mon, 7 Mar 2016 18:47:11 -0500
Subject: Re: [Freesurfer] group analysis all measures same results
what are your command lines?


On 5 March 2016 at 02:01, Kaiming Yin <yinkaiming6...@gmail.com> wrote:

> Dear guys,
>
> I was doing group analysis (command-line) on two groups (patients and
> control, no age or other information). The data has been "qcached", and
> after following the three steps as "mris_preproc, mri_glmfit and
> mri_glmfit-sim" shown in the tutorial on the Freesurfer website, I obtained
> the difference on thickness in both left and right hemispheres, which seems
> great. However, when I repeated the above steps on other measures, e.g.
> area, area.pial, volume (also replaced the parts of "thickness" in the
> command lines), the results seemed to be exactly the same again as those in
> the thickness comparison, even the p-value numbers in the file
> "cache.th40.neg.sig.cluster.summary" were the same. I was using Freesurfer
> v6.0-beta, and I performed the individual data analysis on a linux cluster
> and I copied/downloaded the whole "qcached" subject directory to my linux
> laptop to perform the group comparison, both using the same version of
> Freesurfer, does it matter? Or do you know why it happened like this?
>
> Thanks,
> Kaiming
>
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