Hi,

I have gotten the lh and rh ROIs stats with mris_anatomical_stats before,
is there any statistical tests in particular that you recommend for
asymmetry? What I have done is a two-way anova and paired t-test with
Bonferroni correction. Would like to hear your opinion on that.

Also, I would be interested in the vertex-wise analysis, I will look into
that. How can I do the xhemi analysis after make_folding_atlas?

Thank you!
Daiana

On Tue, Nov 1, 2016 at 5:22 PM, Douglas N Greve <gr...@nmr.mgh.harvard.edu>
wrote:

> You can certainly get the lh and rh ROI stats in table form and then do
> an asymmetry analysis. Or you can use the xhemi stream to do a
> vertex-wise analysis. the difference is the difference between ROI and
> map-based analysis
>
>
> On 11/01/2016 03:47 PM, Daya P wrote:
> > Thank you a lot!
> >
> > I will try this. I had another question regarding statistical analysis
> > for asymmetry. I have seen several papers that take the measures that
> > come from freesurfer (i.e. cortical thickness of auditory cortex), and
> > use MATLAB or SPSS to run statistical tests.
> >
> > I am looking at 13 regions in each hemisphere and want to check for
> > asymmetry across 9 participants. Is there a way to do this within
> > Freesurfer?
> > Otherwise, I am still looking into what the most appropriate test and
> > post hoc test would be. From asking several people there doesn't seem
> > to be a straight answer.
> >
> > Thank you,
> > Daiana
> >
> > On Tue, Nov 1, 2016 at 12:51 PM, Douglas N Greve
> > <gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu>> wrote:
> >
> >     I've written a script that will come out with version 6, but I've
> >     put it
> >     here
> >
> >     https://gate.nmr.mgh.harvard.edu/safelinks/greve/make_folding_atlas
> >     <https://gate.nmr.mgh.harvard.edu/safelinks/greve/make_folding_atlas
> >
> >
> >     I think it should work in 5.3, but I'm not sure. If not, you can
> >     download the dev version and make the atlas using that. Run it with
> >     --help to get info on how to run it.
> >
> >
> >
> >     On 10/28/2016 05:10 PM, Daya P wrote:
> >     > Hi Doug,
> >     >
> >     > I needed to make a registration template and an cortical atlas
> >     because
> >     > I am trying to measure cortical thickness, GM and surface area
> >     on cat
> >     > brains.
> >     >
> >     > What would be the necessary changes?
> >     > Would it be possible (and appropriate) to use just
> >     > mris_left_right_register instead?
> >     >
> >     > Daiana
> >     >
> >     > On Fri, Oct 28, 2016 at 11:34 AM, Douglas Greve
> >     > <gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu>
> >     <mailto:gr...@nmr.mgh.harvard.edu
> >     <mailto:gr...@nmr.mgh.harvard.edu>>> wrote:
> >     >
> >     >     A difference of 10 out of 500 or 1000 does not both me at
> >     all. Why
> >     >     do you need to create your own atlas? It is doable for the
> cross
> >     >     hemi stuff, it is just difficult.
> >     >
> >     >
> >     >     On 10/26/16 10:16 AM, Daya P wrote:
> >     >>
> >     >>     Thank you for your help!
> >     >>
> >     >>     I created a registration template and atlas from scratch
> >     could I
> >     >>     input that in the interhemispheric registration analysis?
> >     >>
> >     >>     The ROIs for the diffrerent regions per hemisphere are 50-100
> >     >>     vertices
> >     >>
> >     >>     On Oct 24, 2016 5:03 PM, "Douglas N Greve"
> >     >>     <gr...@nmr.mgh.harvard.edu
> >     <mailto:gr...@nmr.mgh.harvard.edu>
> >     <mailto:gr...@nmr.mgh.harvard.edu
> >     <mailto:gr...@nmr.mgh.harvard.edu>>> wrote:
> >     >>
> >     >>         It would depend on how big the ROI is to begin with. Do
> you
> >     >>         know that we
> >     >>         have our own interhemispheric analysis that might be
> better
> >     >>         for this?
> >     >>         Check out
> >     >>
> >     >> http://surfer.nmr.mgh.harvard.edu/fswiki/Xhemi
> >     <http://surfer.nmr.mgh.harvard.edu/fswiki/Xhemi>
> >     >>         <http://surfer.nmr.mgh.harvard.edu/fswiki/Xhemi
> >     <http://surfer.nmr.mgh.harvard.edu/fswiki/Xhemi>>
> >     >>
> >     >>
> >     >>         On 10/24/2016 12:33 PM, Daya P wrote:
> >     >>         > Hi Bruce,
> >     >>         >
> >     >>         > I drew ROIs on an initial subject and then after
> >     >>         registering all other
> >     >>         > subjects to the initial one, used mri_label2label to map
> >     >>         the ROIs from
> >     >>         > the initial subject to subsequent ones.
> >     >>         > I am interested in looking at asymmetry between left and
> >     >>         right regions.
> >     >>         >
> >     >>         > I had two concerns, one that the ROIs have different #
> >     >>         vertices on
> >     >>         > different subjects, but as you mentioned the nonlinear
> >     >>         process makes
> >     >>         > sense, since each subject does not have the exact same
> >     >>         brain size and
> >     >>         > curvature.
> >     >>         >
> >     >>         > Another concern was that the ROIs on the left and right
> >     >>         hemisphere in
> >     >>         > a subject do not have the exact same number of vertices.
> >     >>         Would a
> >     >>         > difference of 10 vertices max bias results?
> >     >>         >
> >     >>         > Thank you for your help,
> >     >>         >
> >     >>         > Daiana R. Pur
> >     >>         > Research Assistant
> >     >>         > Canadian Surgical Technologies & Advanced Robotics
> >     >>         > Brain and Mind Institute
> >     >>         > Western University
> >     >>         > London, ON, N6A 5B7
> >     >>         > Canada
> >     >>         >
> >     >>         > On Mon, Oct 24, 2016 at 12:09 PM, Bruce Fischl
> >     >>         > <fis...@nmr.mgh.harvard.edu
> >     <mailto:fis...@nmr.mgh.harvard.edu>
> >     >>         <mailto:fis...@nmr.mgh.harvard.edu
> >     <mailto:fis...@nmr.mgh.harvard.edu>>
> >     >>         <mailto:fis...@nmr.mgh.harvard.edu
> >     <mailto:fis...@nmr.mgh.harvard.edu>
> >     >>         <mailto:fis...@nmr.mgh.harvard.edu
> >     <mailto:fis...@nmr.mgh.harvard.edu>>>> wrote:
> >     >>         >
> >     >>         >     Hi Daiana
> >     >>         >
> >     >>         >     yes, that is to be expected given the nonlinear
> >     nature
> >     >>         of the
> >     >>         >     cross-subject registration. It shouldn't bias
> things,
> >     >>         although
> >     >>         >     you'll need to give us more details if you want a
> >     more
> >     >>         definitive
> >     >>         >     answer.
> >     >>         >
> >     >>         >     cheers
> >     >>         >     Bruce
> >     >>         >
> >     >>         >
> >     >>         >
> >     >>         >     On Mon, 24 Oct 2016, Daya P wrote:
> >     >>         >
> >     >>         >         Hi All,
> >     >>         >
> >     >>         >         My question is about using mri_label2label. When
> >     >>         mapping the
> >     >>         >         labels from one
> >     >>         >         subject to another the number of vertices of
> each
> >     >>         ROI is
> >     >>         >         different. Is that
> >     >>         >         something to be expected?
> >     >>         >
> >     >>         >         How much of a difference does a number of
> >     vertices
> >     >>         of 50
> >     >>         >         compare to 40 have
> >     >>         >         on measures like thickness, grey matter and
> >     surface
> >     >>         area?
> >     >>         >
> >     >>         >         I would really appreciate some help
> >     >>         >
> >     >>         >         Thank you,
> >     >>         >
> >     >>         >         Daiana R. Pur
> >     >>         >         Research Assistant
> >     >>         >         Canadian Surgical Technologies & Advanced
> >     Robotics
> >     >>         >         Brain and Mind Institute
> >     >>         >         Western University
> >     >>         >         London, ON, N6A 5B7
> >     >>         >         Canada
> >     >>         >
> >     >>         >
> >     >>         >
> >     >>         >     _______________________________________________
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> >     >>         >
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> >     >>         >
> >     >>
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> >     <https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer>
> >     >>
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> >     >>         >
> >     >>         >
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> >     >>         >
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> >     >>
> >     >>         --
> >     >>         Douglas N. Greve, Ph.D.
> >     >>         MGH-NMR Center
> >     >> gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu>
> >     <mailto:gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu
> >>
> >     >>         Phone Number: 617-724-2358 <tel:617-724-2358>
> >     <tel:617-724-2358 <tel:617-724-2358>>
> >     >>         Fax: 617-726-7422 <tel:617-726-7422> <tel:617-726-7422
> >     <tel:617-726-7422>>
> >     >>
> >     >>         Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
> >     <http://surfer.nmr.mgh.harvard.edu/fswiki/BugReporting>
> >     >>         <http://surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
> >     <http://surfer.nmr.mgh.harvard.edu/fswiki/BugReporting>>
> >     >>         FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2
> >     <https://gate.nmr.mgh.harvard.edu/filedrop2>
> >     >>         <https://gate.nmr.mgh.harvard.edu/filedrop2
> >     <https://gate.nmr.mgh.harvard.edu/filedrop2>>
> >     >> www.nmr.mgh.harvard.edu/facility/filedrop/index.html
> >     <http://www.nmr.mgh.harvard.edu/facility/filedrop/index.html>
> >     >>
> >      <http://www.nmr.mgh.harvard.edu/facility/filedrop/index.html
> >     <http://www.nmr.mgh.harvard.edu/facility/filedrop/index.html>>
> >     >>         Outgoing:
> >     >> ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/
> >     <ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/>
> >     >>         <ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/
> greve/
> >     <ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/>>
> >     >>
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> >     >>
> >     >>
> >     >>
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> >     >     _______________________________________________ Freesurfer
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> >     >     information in this e-mail is intended only for the person
> >     to whom
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> >     >     error and the e-mail contains patient information, please
> >     contact
> >     >     the Partners Compliance HelpLine at
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> >     --
> >     Douglas N. Greve, Ph.D.
> >     MGH-NMR Center
> >     gr...@nmr.mgh.harvard.edu <mailto:gr...@nmr.mgh.harvard.edu>
> >     Phone Number: 617-724-2358 <tel:617-724-2358>
> >     Fax: 617-726-7422 <tel:617-726-7422>
> >
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> >     <http://surfer.nmr.mgh.harvard.edu/fswiki/BugReporting>
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> >     _______________________________________________
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> harvard.edu>
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> >
> >
> >
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>
> --
> Douglas N. Greve, Ph.D.
> MGH-NMR Center
> gr...@nmr.mgh.harvard.edu
> Phone Number: 617-724-2358
> Fax: 617-726-7422
>
> Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
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> www.nmr.mgh.harvard.edu/facility/filedrop/index.html
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