Thanks, Doug.
There is no significant interaction and I merged the males and females within each group, but the reviewer wants me to include gender as a covariate. Do we always need to control for gender esp. when the group x gender is insignificant? Will that be "over-controlled"? ________________________________ From: freesurfer-boun...@nmr.mgh.harvard.edu <freesurfer-boun...@nmr.mgh.harvard.edu> on behalf of Douglas N Greve <gr...@nmr.mgh.harvard.edu> Sent: 06 April 2017 20:45 To: freesurfer@nmr.mgh.harvard.edu Subject: Re: [Freesurfer] QDEC-volume, thickness and area what do you mean they do not differ in gender ratio? Just that the relative number of M/F is the same in each group? If there is not a significant interaction between gender and group, then you can usually merge the genders. On 04/05/2017 05:13 PM, Lim, Lena wrote: > > Dear Freesurfer Experts, > > 1) I have 2 groups (A & B), which do not differ in terms of gender > ratio. If there were no significant regions for Group-Gender > interaction in mean cortical thickness in the QDEC analysis, can I > conclude that gender does not influence the effect of group on > thickness? The differences between A and B on mean thickness is not > affected by Gender? Is this valid or do I need to add Gender as a > covariate even though the group do not differ on gender ratio? > > 2) A reviewer pointed that it is not right to test for group > differences in volume once I have tested for thickness and area, > especially when there is a cluster where A and B do not differ > significantly in thickness and area but they differ significantly in > volume…Is this right? > > Please kindly advise. > > Many thanks, > > Lena > > > > _______________________________________________ > Freesurfer mailing list > Freesurfer@nmr.mgh.harvard.edu > https://emea01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fmail.nmr.mgh.harvard.edu%2Fmailman%2Flistinfo%2Ffreesurfer&data=01%7C01%7Clena.lim%40kcl.ac.uk%7C1a7a3062e8634c0e8d1c08d47d2577ca%7C8370cf1416f34c16b83c724071654356%7C0&sdata=PhNkIdT%2Fj8FHEIG2Wo1UjfG65ns90Ao7ajxUX7ErJus%3D&reserved=0 -- Douglas N. Greve, Ph.D. MGH-NMR Center gr...@nmr.mgh.harvard.edu Phone Number: 617-724-2358 Fax: 617-726-7422 Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting FileDrop: https://emea01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fgate.nmr.mgh.harvard.edu%2Ffiledrop2&data=01%7C01%7Clena.lim%40kcl.ac.uk%7C1a7a3062e8634c0e8d1c08d47d2577ca%7C8370cf1416f34c16b83c724071654356%7C0&sdata=sLX6wB91T%2FSYsH2ihNMK39jOGhYZgcSWos3D2cfO0RE%3D&reserved=0 https://emea01.safelinks.protection.outlook.com/?url=www.nmr.mgh.harvard.edu%2Ffacility%2Ffiledrop%2Findex.html&data=01%7C01%7Clena.lim%40kcl.ac.uk%7C1a7a3062e8634c0e8d1c08d47d2577ca%7C8370cf1416f34c16b83c724071654356%7C0&sdata=uCgDjaHFBNRCI0uSukR9fcgOVVo6Fhr5gGZIJslPy4E%3D&reserved=0 Outgoing: ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/ _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://emea01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fmail.nmr.mgh.harvard.edu%2Fmailman%2Flistinfo%2Ffreesurfer&data=01%7C01%7Clena.lim%40kcl.ac.uk%7C1a7a3062e8634c0e8d1c08d47d2577ca%7C8370cf1416f34c16b83c724071654356%7C0&sdata=PhNkIdT%2Fj8FHEIG2Wo1UjfG65ns90Ao7ajxUX7ErJus%3D&reserved=0 The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at https://emea01.safelinks.protection.outlook.com/?url=http%3A%2F%2Fwww.partners.org%2Fcomplianceline&data=01%7C01%7Clena.lim%40kcl.ac.uk%7C1a7a3062e8634c0e8d1c08d47d2577ca%7C8370cf1416f34c16b83c724071654356%7C0&sdata=fCWNr93ZrBggNtOlph5yLyklpklGrCz3ZH2aREJ8WoY%3D&reserved=0 . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail.
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