probably so. It is up to you whether you want to fight the reviewer or not.
On 04/06/2017 05:08 PM, Lim, Lena wrote: > > Thanks, Doug. > > > There is no significant interaction and I merged the males and females > within each group, but the reviewer wants me to include gender as a > covariate. Do we always need to control for gender esp. when the group > x gender is insignificant? Will that be "over-controlled"? > > > > ------------------------------------------------------------------------ > *From:* freesurfer-boun...@nmr.mgh.harvard.edu > <freesurfer-boun...@nmr.mgh.harvard.edu> on behalf of Douglas N Greve > <gr...@nmr.mgh.harvard.edu> > *Sent:* 06 April 2017 20:45 > *To:* freesurfer@nmr.mgh.harvard.edu > *Subject:* Re: [Freesurfer] QDEC-volume, thickness and area > what do you mean they do not differ in gender ratio? Just that the > relative number of M/F is the same in each group? If there is not a > significant interaction between gender and group, then you can usually > merge the genders. > > > On 04/05/2017 05:13 PM, Lim, Lena wrote: > > > > Dear Freesurfer Experts, > > > > 1) I have 2 groups (A & B), which do not differ in terms of gender > > ratio. If there were no significant regions for Group-Gender > > interaction in mean cortical thickness in the QDEC analysis, can I > > conclude that gender does not influence the effect of group on > > thickness? The differences between A and B on mean thickness is not > > affected by Gender? Is this valid or do I need to add Gender as a > > covariate even though the group do not differ on gender ratio? > > > > 2) A reviewer pointed that it is not right to test for group > > differences in volume once I have tested for thickness and area, > > especially when there is a cluster where A and B do not differ > > significantly in thickness and area but they differ significantly in > > volume…Is this right? > > > > Please kindly advise. > > > > Many thanks, > > > > Lena > > > > > > > > _______________________________________________ > > Freesurfer mailing list > > Freesurfer@nmr.mgh.harvard.edu > > > https://emea01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fmail.nmr.mgh.harvard.edu%2Fmailman%2Flistinfo%2Ffreesurfer&data=01%7C01%7Clena.lim%40kcl.ac.uk%7C1a7a3062e8634c0e8d1c08d47d2577ca%7C8370cf1416f34c16b83c724071654356%7C0&sdata=PhNkIdT%2Fj8FHEIG2Wo1UjfG65ns90Ao7ajxUX7ErJus%3D&reserved=0 > > -- > Douglas N. Greve, Ph.D. > MGH-NMR Center > gr...@nmr.mgh.harvard.edu > Phone Number: 617-724-2358 > Fax: 617-726-7422 > > Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting > FileDrop: > https://emea01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fgate.nmr.mgh.harvard.edu%2Ffiledrop2&data=01%7C01%7Clena.lim%40kcl.ac.uk%7C1a7a3062e8634c0e8d1c08d47d2577ca%7C8370cf1416f34c16b83c724071654356%7C0&sdata=sLX6wB91T%2FSYsH2ihNMK39jOGhYZgcSWos3D2cfO0RE%3D&reserved=0 > https://emea01.safelinks.protection.outlook.com/?url=www.nmr.mgh.harvard.edu%2Ffacility%2Ffiledrop%2Findex.html&data=01%7C01%7Clena.lim%40kcl.ac.uk%7C1a7a3062e8634c0e8d1c08d47d2577ca%7C8370cf1416f34c16b83c724071654356%7C0&sdata=uCgDjaHFBNRCI0uSukR9fcgOVVo6Fhr5gGZIJslPy4E%3D&reserved=0 > Outgoing: ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/ > > _______________________________________________ > Freesurfer mailing list > Freesurfer@nmr.mgh.harvard.edu > https://emea01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fmail.nmr.mgh.harvard.edu%2Fmailman%2Flistinfo%2Ffreesurfer&data=01%7C01%7Clena.lim%40kcl.ac.uk%7C1a7a3062e8634c0e8d1c08d47d2577ca%7C8370cf1416f34c16b83c724071654356%7C0&sdata=PhNkIdT%2Fj8FHEIG2Wo1UjfG65ns90Ao7ajxUX7ErJus%3D&reserved=0 > > > The information in this e-mail is intended only for the person to whom > it is > addressed. If you believe this e-mail was sent to you in error and the > e-mail > contains patient information, please contact the Partners Compliance > HelpLine at > https://emea01.safelinks.protection.outlook.com/?url=http%3A%2F%2Fwww.partners.org%2Fcomplianceline&data=01%7C01%7Clena.lim%40kcl.ac.uk%7C1a7a3062e8634c0e8d1c08d47d2577ca%7C8370cf1416f34c16b83c724071654356%7C0&sdata=fCWNr93ZrBggNtOlph5yLyklpklGrCz3ZH2aREJ8WoY%3D&reserved=0 > > . If the e-mail was sent to you in error > but does not contain patient information, please contact the sender > and properly > dispose of the e-mail. > > > > _______________________________________________ > Freesurfer mailing list > Freesurfer@nmr.mgh.harvard.edu > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer -- Douglas N. Greve, Ph.D. MGH-NMR Center gr...@nmr.mgh.harvard.edu Phone Number: 617-724-2358 Fax: 617-726-7422 Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2 www.nmr.mgh.harvard.edu/facility/filedrop/index.html Outgoing: ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/ _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail.
