Is this still a problem?

On 07/11/2017 09:51 AM, Paul Glad Mihai wrote:
> Hi Bruce,
>
> Thanks for the quick reply. I've just finished rerunning it with spm,
> fsl and header init and the latter seemed to work if I write out a
> _bbreg.nii file. The former two failed, however. Apparently using the
> header seems to work for this one subject and one run. I'm testing the
> rest of the runs.
>
> This is an example from the FSL init. Please note that I'm running it
> through nipype, hence the jumbled subdirectory strucutre.
>
> bbregister --t2 --epi-mask --init-fsl --fslmat
> /data/pt_nmc002/TDMGB_FMRI_coreg/tmp/preproc/_subject_id_sub-01/_init_fsl/bbreg/mapflow/_bbreg0/meanusub-01_task-spespk_run-01_bold_bbreg_sub-01.mat
> --reg
> /data/pt_nmc002/TDMGB_FMRI_coreg/tmp/preproc/_subject_id_sub-01/_init_fsl/bbreg/mapflow/_bbreg0/meanusub-01_task-spespk_run-01_bold_bbreg_sub-01.dat
> --o
> /data/pt_nmc002/TDMGB_FMRI_coreg/tmp/preproc/_subject_id_sub-01/_init_fsl/bbreg/mapflow/_bbreg0/meanusub-01_task-spespk_run-01_bold_bbreg.nii
> --mov
> /data/pt_nmc002/TDMGB_FMRI_coreg/tmp/preproc/_subject_id_sub-01/_init_fsl/bbreg/mapflow/_bbreg0/meanusub-01_task-spespk_run-01_bold.nii
> --s sub-01
>
> The output is attached. Details are under the heading 'Terminal output'.
> I'm also attaching a screenshot of the T2 with a white overlay for the
> header init. It seems to be alright. The output from the header init is
> also attached. The difference in the command line is --init-header
> instead of --init-fsl.
>
> Downstream, however, the registration to MNI through ANTs seems to fail,
> even though I've converted the transformation matrices to ITK through
> C3D. Hmmmm... I just had a revelation. I may have used the wrong T1 to
> calculate the registration matrix through ANTs. Instead of using the T1
> from the ReconAll output, I used the one from the fsl.bet. I'll make
> sure to use the ReconAll T1 and get back to you.
>
> I would appreciate a comment, however, on how to get better registration
> of partial FoV T2 images to T1 images through BBRegister. It seems that
> the easiest option is a full head EPI at the time of the experiment.
>
> Regards,
> Glad
>
>
>
> On 07/11/2017 03:33 PM, Bruce Fischl wrote:
>> Hi Glad
>>
>> can you send us the full command line you are using and screen output?
>>
>> thanks
>>
>> Bruce
>> On
>> Tue, 11 Jul 2017, Paul Glad Mihai wrote:
>>
>>> Dear List,
>>>
>>> I've been quite frustrated with the BBRegister results when trying to
>>> register a partial field of view EPI mean functional image to a T1 scan.
>>> I've tried different init arguments (fsl, spm, header) and none really
>>> work. I've found that the initial registration is causing the problem,
>>> since the T1 and mean EPi are in reasonable alignment, but not perfect.
>>> As soon as it passes the initial alignment it's totally off and
>>> obviously fails in the BBR step. I have no full head EPI, unfortunately.
>>> I have a full head scout which seems to be a T1 image with really poor
>>> contrast. If I try to register this to the T1 through BBRegister it
>>> works. But if I use it as an intermediate file it still fails. What can
>>> I do? How does the intermediate file come into play? Will it get
>>> registered to the T1 initially and then the resulting matrix is used
>>> further? I also tried to feed the resulting registration matrix as
>>> init-reg but that didn't work either.
>>>
>>> Is there a way to skip the initial registration?
>>>
>>> Can I mask the T1 image with the FoV of the functional scan if they are
>>> initially in reasonable alignment? Would that work? Would that mean that
>>> I have to re-run ReconAll with the masked T1?
>>>
>>> Would love to hear back from someone.
>>>
>>> Regards,
>>> Glad
>>>
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Douglas N. Greve, Ph.D.
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