So far it isn't anymore. It's more of a problem with ANTs now.
BBRegister works with --init-header for partial FoV T1 and mean EPI are
more or less in alignment. But if they wouldn't be then one would have a
problem with registration.

On 07/13/2017 12:35 AM, Douglas N Greve wrote:
> Is this still a problem?
> 
> On 07/11/2017 09:51 AM, Paul Glad Mihai wrote:
>> Hi Bruce,
>>
>> Thanks for the quick reply. I've just finished rerunning it with spm,
>> fsl and header init and the latter seemed to work if I write out a
>> _bbreg.nii file. The former two failed, however. Apparently using the
>> header seems to work for this one subject and one run. I'm testing the
>> rest of the runs.
>>
>> This is an example from the FSL init. Please note that I'm running it
>> through nipype, hence the jumbled subdirectory strucutre.
>>
>> bbregister --t2 --epi-mask --init-fsl --fslmat
>> /data/pt_nmc002/TDMGB_FMRI_coreg/tmp/preproc/_subject_id_sub-01/_init_fsl/bbreg/mapflow/_bbreg0/meanusub-01_task-spespk_run-01_bold_bbreg_sub-01.mat
>> --reg
>> /data/pt_nmc002/TDMGB_FMRI_coreg/tmp/preproc/_subject_id_sub-01/_init_fsl/bbreg/mapflow/_bbreg0/meanusub-01_task-spespk_run-01_bold_bbreg_sub-01.dat
>> --o
>> /data/pt_nmc002/TDMGB_FMRI_coreg/tmp/preproc/_subject_id_sub-01/_init_fsl/bbreg/mapflow/_bbreg0/meanusub-01_task-spespk_run-01_bold_bbreg.nii
>> --mov
>> /data/pt_nmc002/TDMGB_FMRI_coreg/tmp/preproc/_subject_id_sub-01/_init_fsl/bbreg/mapflow/_bbreg0/meanusub-01_task-spespk_run-01_bold.nii
>> --s sub-01
>>
>> The output is attached. Details are under the heading 'Terminal output'.
>> I'm also attaching a screenshot of the T2 with a white overlay for the
>> header init. It seems to be alright. The output from the header init is
>> also attached. The difference in the command line is --init-header
>> instead of --init-fsl.
>>
>> Downstream, however, the registration to MNI through ANTs seems to fail,
>> even though I've converted the transformation matrices to ITK through
>> C3D. Hmmmm... I just had a revelation. I may have used the wrong T1 to
>> calculate the registration matrix through ANTs. Instead of using the T1
>> from the ReconAll output, I used the one from the fsl.bet. I'll make
>> sure to use the ReconAll T1 and get back to you.
>>
>> I would appreciate a comment, however, on how to get better registration
>> of partial FoV T2 images to T1 images through BBRegister. It seems that
>> the easiest option is a full head EPI at the time of the experiment.
>>
>> Regards,
>> Glad
>>
>>
>>
>> On 07/11/2017 03:33 PM, Bruce Fischl wrote:
>>> Hi Glad
>>>
>>> can you send us the full command line you are using and screen output?
>>>
>>> thanks
>>>
>>> Bruce
>>> On
>>> Tue, 11 Jul 2017, Paul Glad Mihai wrote:
>>>
>>>> Dear List,
>>>>
>>>> I've been quite frustrated with the BBRegister results when trying to
>>>> register a partial field of view EPI mean functional image to a T1 scan.
>>>> I've tried different init arguments (fsl, spm, header) and none really
>>>> work. I've found that the initial registration is causing the problem,
>>>> since the T1 and mean EPi are in reasonable alignment, but not perfect.
>>>> As soon as it passes the initial alignment it's totally off and
>>>> obviously fails in the BBR step. I have no full head EPI, unfortunately.
>>>> I have a full head scout which seems to be a T1 image with really poor
>>>> contrast. If I try to register this to the T1 through BBRegister it
>>>> works. But if I use it as an intermediate file it still fails. What can
>>>> I do? How does the intermediate file come into play? Will it get
>>>> registered to the T1 initially and then the resulting matrix is used
>>>> further? I also tried to feed the resulting registration matrix as
>>>> init-reg but that didn't work either.
>>>>
>>>> Is there a way to skip the initial registration?
>>>>
>>>> Can I mask the T1 image with the FoV of the functional scan if they are
>>>> initially in reasonable alignment? Would that work? Would that mean that
>>>> I have to re-run ReconAll with the masked T1?
>>>>
>>>> Would love to hear back from someone.
>>>>
>>>> Regards,
>>>> Glad
>>>>
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-- 
Paul Glad Mihai, PhD

Independent Research Group "Neural Mechanisms of Human Communication"
Max Planck Institute for Human Cognitive and Brain Sciences
Stephanstraße 1A, 04103 Leipzig, Germany

Phone:   +49 (0) 341-9940-2478
E-mail:  [email protected]

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