I don't know what might have happened (under the hood, mni152reg uses 
the FSL flirt program). If you want a non-linear registration, then 
you'll need to use CVS (mri_cvs_register) and choose the mni target. If 
you just want the aparc of the aparc+aseg, then don't go into the volume 
at all.


On 04/17/2018 01:57 PM, Zimmerman, Jared wrote:
>
> Hi All,
>
> I’m trying to register the aparc+aseg volumes from subject T1 space to 
> MNI152 space and running into problems.  I’ve taken the following steps
>
> 1.mri152reg –s Subj241
>
> 2.mri_vol2vol --targ $FSLDIR/data/standard/MNI152_T1_2mm_brain.nii.gz 
> --mov $SUBJECTS_DIR/Subj241/mri/aparc+aseg.mgz --o 
> Subj241_aparc+aseg_mni2mm.nii.gz --reg 
> $SUBJECTS_DIR/Subj241/mri/transforms/reg.mni152.2mm.dat
>
> This yields an image that is rotated and shrunken relative to the 
> MNI152_T1_2mm template as shown in the attached image.
>
> I’m wondering if this is the right way to do what I’d like to do.  The 
> reg.mni152.2mm.dat file is only a linear transform, but I’d like to 
> apply a non-linear transformation to the subject aparc+aseg to get it 
> well matched to the MNI152 template space.  Some of my subjects have 
> atypical head shapes and I really think a non-linear warp will be 
> necessary to achieve a good fit.
>
> I’ve run the MNI152 1mm template through recon-all so I have that as a 
> reference.  Is there a way to map volumes from one subject space to 
> another via fsaverage or sphere sort of like mri_label2label does for 
> labels?
>
> Alternatively, I could just calculate the appropriate T1 to MNI warps 
> with FNIRT or ANTs and apply those to the aparc+aseg, but I figured it 
> would be possible to do with FreeSurfer without calculating any new 
> transforms.
>
> Thanks,
>
> Jared
>
>
>
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