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Thanks for the help!

On Wed, Dec 4, 2019 at 6:47 PM Greve, Douglas N.,Ph.D. <
dgr...@mgh.harvard.edu> wrote:

> Yes, but threshold it first, eg
> mri_binarize --abs --i sig.cluster.mgh --min .000001 --o newmask.mgh
>
> On 12/4/19 1:38 PM, cody samth wrote:
> >
> >         External Email - Use Caution
> >
> > Thanks, for your input. It's interesting that there isn't a more
> > standard way of approaching it. If i wanted to constrain my post-hoc
> > to be within the cluster(s) from the main effect how would I go about
> > running this through mri_glmfit? Would I include the --mask
> > sig.cluster.mgh in the command for mri_glmfit and then aslo
> > mri_glmfit-sim?
> >
> > On Mon, Dec 2, 2019 at 6:40 PM Greve, Douglas N.,Ph.D.
> > <dgr...@mgh.harvard.edu <mailto:dgr...@mgh.harvard.edu>> wrote:
> >
> >     I don't think there is a standard way to do this. A vertex-wise
> >     analysis is not the same thing as a averaging over a group of
> >     vertices. I guess you could constrain your post-hoc analysis to be
> >     within the main effect cluster; that would be most consistent. But
> >     I don't think you'd have any problems getting it published either
> way.
> >
> >     On 12/2/2019 3:12 PM, cody samth wrote:
> >>
> >>             External Email - Use Caution
> >>
> >>     Hi,
> >>
> >>     I have a statistical question about how to approach reporting
> >>     results from FreeSurfer analyses containing three groups. I ran a
> >>     group effect (F-test) and then post-hoc tests looking at
> >>     pair-wise comparisons between the three groups. My question is
> >>     why is that we run separate vertex-wise analyses for the
> >>     post-hocs rather than extracting the values from significant
> >>     clusters and running post-hocs in a statistical software for just
> >>     the regions where a significance difference was found (ie the
> >>     clusters)? As a post-hoc vertex wide analysis can lead to
> >>     different results.
> >>
> >>     For example in my group effect contrasts I found a cluster in the
> >>     parietal lobe. Whereas in my post hoc-vertex wide analyses one of
> >>     them found two clusters 1) within the parietal 2) within the
> >>     frontal lobe. If I choose to run these post-hoc analyses via
> >>     freesurfer (ie vertex-wise) rather than extracting the results to
> >>     analyze in a statistical program, is it standard to report the
> >>     second cluster? Even though it didn't come up in the group model?
> >>     If so is there a paper that people reference that uses this
> approach?
> >>
> >>     Thanks,
> >>     Cody
> >>
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