External Email - Use Caution        

Thank your very much Douglas for the information. Much appreciated.


On Tue, Jan 28, 2020 at 1:12 PM Greve, Douglas N.,Ph.D. <
dgr...@mgh.harvard.edu> wrote:

> The symmetric GTM is the default (the non-sym is  not implemented).
>
> I highly recommend that you don't use melzter (which is why I did not have
> docs for it:). But if you must run it, add --melzter BinThresh MaskThresh
> nDilations
> BinThresh is used to create a binary mask by thresholding the WM+GM tissue
> fraction maps at BinThresh. This is a number between 0 and 1
> nDilations is the number of times that the binary mask is dilated to
> expand it a bit (don't use more than 2)
> MaskThresh - the binarized mask is smoothed and then divided into the PET
> image to do the correction. Voxels whose smoothed value is less than
> MaskThresh is set to 0. MaskThresh should be between 0 and 1
>
> this is all kind of messy and unprincipled and the results are very
> sensitive to the values you set above . which is why I avoid it.
>
> On 1/27/2020 9:23 PM, Kate Marvel wrote:
>
>         External Email - Use Caution
> Thanks Douglas.
>
> I checked the mri_gtmpvc --help command  but the arguments for symmetric
> Geometric Transfer Matrix and two-component model (Meltzer)
> are missing. See the output below:
>
> USAGE: mri_gtmpvc
>
>    --i   inputvol : source data to PVC
>          --frame F : only process 0-based frame F from inputvol
>    --psf psfmm : scanner PSF FWHM in mm
>    --seg segfile : anatomical segmentation to define regions for GTM
>    --reg reg.lta : LTA registration file that maps anatomical to PET
>    --regheader : assume input and seg share scanner space
>    --o   outdir    : output directory
>
>    --mask volfile : ignore areas outside of the mask (in input vol space)
>    --auto-mask FWHM thresh : automatically compute mask
>    --no-reduce-fov : do not reduce FoV to encompass automask
>    --C contrast.mtx : univariate contrast to test (ascii text file)
>
>    --default-seg-merge : default schema for merging ROIs
>    --merge-hypos : merge left and right hypointensites into to ROI
>    --merge-cblum-wm-gyri : cerebellum WM gyri back into cerebellum WM
>    --tt-reduce : reduce segmentation to that of a tissue type
>    --replace Id1 Id2 : replace seg Id1 with seg Id2
>    --replace-file : file with a list of Ids to replace
>    --reg-identity : assume that input is in anatomical space
>    --rescale Id1 <Id2...>  : specify reference region(s) used to rescale
> (default is pons)
>    --no-rescale   : do not global rescale such that mean of reference
> region is scaleref
>    --scale-refval refval : scale such that mean in reference region is
> refval
>
>    --no-tfe : do not correction for tissue fraction effect (with --psf 0
> turns off PVC entirely)
>    --rbv             : perform RBV PVC
>    --rbv-res voxsize : set RBV voxel resolution (good for when standard
> res takes too much memory)
>    --mg gmthresh RefId1 RefId2 ...: perform Mueller-Gaertner PVC, gmthresh
> is min gm pvf bet 0 and 1
>    --mg-ref-cerebral-wm : set MG RefIds to 2 and 41
>    --mg-ref-lobes-wm : set MG RefIds to those for lobes when using wm
> subseg
>    --mgx gmxthresh : GLM-based Mueller-Gaertner PVC, gmxthresh is min gm
> pvf bet 0 and 1
>    --km-ref RefId1 RefId2 ... : compute reference TAC for KM as mean of
> given RefIds
>    --km-hb  RefId1 RefId2 ... : compute HiBinding TAC for KM as mean of
> given RefIds
>    --ss bpc scale dcf : steady-state analysis spec blood plasma
> concentration, unit scale
>      and decay correction factor. You must also spec --km-ref. Turns off
> rescaling
>
>    --X : save X matrix in matlab4 format as X.mat (it will be big)
>    --y : save y matrix in matlab4 format as y.mat
>    --beta : save beta matrix in matlab4 format as beta.mat
>    --X0 : save X0 matrix in matlab4 format as X0.mat (it will be big)
>    --save-input : saves rescaled input as input.rescaled.nii.gz
>    --save-eres : saves residual error
>    --save-yhat : saves yhat
>    --save-yhat-with-noise seed nreps : saves yhat with noise, seed < 0 for
> TOD
>    --save-yhat-full-fov : saves yhat in full FoV (if FoV was reduced)
>    --save-yhat0 : saves yhat prior to smoothing
>
>    --synth gtmbeta C R S MBs seed nreps : synthesize volume with gtmbeta
> as input
>        spec all other inputs the same; CRS are PSF for col, row, slice,
> MBs motion blur slope
>        seed=0 for no noise, -1 for TOD seed. Turns on VFC for synth
>        but returns it to its specified value for analysis
>    --synth-only : exit after doing synthesis (implies --synth-save)
>    --synth-save : with --synth saves synthesized volume to
> outdir/synth.nii.gz
>
>    --threads N : use N threads (with Open MP)
>    --max-threads : use the maximum allowable number of threads for this
> computer
>    --max-threads-minus-1 : use one less than the maximum allowable number
> of threads for this computer
>    --sd SUBJECTS_DIR
>    --vg-thresh thrshold : threshold for  'ERROR: LTAconcat(): LTAs 0 and 1
> do not match'
>    --gdiag diagno : set diagnostic level
>    --debug     turn on debugging
>    --checkopts don't run anything, just check options and exit
>    --help      print out information on how to use this program
>    --version   print out version and exit
>
> Thanks,
>
> On Mon, Jan 27, 2020 at 6:03 PM Greve, Douglas N.,Ph.D. <
> dgr...@mgh.harvard.edu> wrote:
>
>> Run it with --help. Also look at the PETsurfer wiki page for typical usage
>>
>> On 1/27/2020 3:54 PM, Kate Marvel wrote:
>>
>>         External Email - Use Caution
>> Hi Freesurfer community,
>>
>> I would like to know the arguments to use for symmetric Geometric
>> Transfer Matrix and two-compartment model (Meltzer Method) in the
>> petsurfer command "mri_gtmpvc".
>>
>> Thank you,
>>
>> --
>> kate
>>
>> _______________________________________________
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>
>
>
> --
> kate
>
> _______________________________________________
> Freesurfer mailing 
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-- 
kate
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