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 I am interested in obtaining the average intensity within a label from each 
frame of a functional image that has been smoothed on the surface  (I have 
generated the label). However, the functional connectivity pipeline seems to 
use only volume based seeds. It seems to me that in using the FreeSurfer 
software we would want to take advantage of the surface based smoothing and not 
return to getting the average of voxels in aparc+aseg. 

(1) Am I incorrect in my thinking here?

(2) Is there a way to get the mean intensity of a label (I have created) at 
each frame along the surface to get a timcourse for a particular region?

I see there is a way to do this with anatomical features such as thickness, but 
I do not see a way to do this with functional data across frames for signal 
intensity. 

Thanks
~Erik Jahner




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