External Email - Use Caution        

Hi Doug,

Nevermind to my first question! I read this post 
(https://secure-web.cisco.com/1646ymi0_yM9ab72e81bZdCKw_zNbXr9RihxDaiDVPq0_Qd4EXYgDmO56zQdi9l_AyV3uyyiURXHoYWQmiu56CbMuIGdZz8EH0gbsnVrAz9KwunZAwLzh0kh-jzVwHtlbEdd1ExEJYHT7o7JtUWg2GM484JTyL0VZJymRuGRyD0ag1nQ_0BPPjQHxPCqNHEU4Y_seBsq9XsUROgyR-bX-tHVXxhshVUHgneudw6tEB2lIVYfYrL3srRbjy1QN9Bq_e3_WaNCDhkXdixnae24i41HHYwJfn3KwsmNoZ2RxLoh3SMkXXwVntAewl8PeldBY0s3UxoEPiFbDdXXuJLUjlw/https%3A%2F%2Fwww.mail-archive.com%2Ffreesurfer%40nmr.mgh.harvard.edu%2Fmsg32235.html)
 and realized that we always include a subject-specific par file in each run 
for first-level analyses.

However, I’m still confused about how to modify my paradigm file. I also need 
to model the trials of non-interest, so would it be as follows?

0             1              2.5          1.0          SelfOffset
0              2              2.5          1.0          SelfSlope (equal to 
subject’s rating of self-relevance)
0              3              2.5          1.0          ValenceOffset
0              4              2.5          3.0          ValenceSlope (equal to 
subject’s rating of valence)

2.5          0              2.5          1.0          FIXATION

5.0          1              2.5          1.0          SelfOffset
5.0          2              2.5          0              SelfSlope (equal to 
subject’s rating of self-relevance, in this case subject responded 0, or 
non-relevant)
5.0          3              2.5          1.0          ValenceOffset
5.0          4              2.5          2.0          ValenceSlope (equal to 
subject’s rating of valence)

7.5          5              2.5          1.0          OTHER

Do these contrasts look correct to you?
Self vs Fixation -a 1 -c 0 (main effect of self)
Valence vs Fixation -a 3 -c 0 (main effect of valence)
Self vs Valence -a 2 -a 4 (interaction between self x valence)

Thank you so much for your help!
Angela

From: <freesurfer-boun...@nmr.mgh.harvard.edu> on behalf of Angela Fang 
<angf...@uw.edu>
Reply-To: Freesurfer support list <freesurfer@nmr.mgh.harvard.edu>
Date: Thursday, July 28, 2022 at 1:02 PM
To: Freesurfer support list <freesurfer@nmr.mgh.harvard.edu>
Subject: Re: [Freesurfer] FSFAST first level covariates

Thanks Doug. This wiki page is extremely helpful. However, my question is about 
individual subject responses. I could see how you could include a summary 
(e.g., average) value of the parametric variable across subjects in your 
“weight” column but it’s not clear to me how you could integrate individual 
subject responses to each word in the parametric modulation paradigm file? I’m 
imagining something like the FSGD file where a value is given for each subject, 
but for first-level analysis.

We have a similar design as someone else who posted a similar question 
(https://secure-web.cisco.com/11nFbIrJYBqRI1W_4wY-HvfdEF3GG6xLL8So8t0i9yKbcElVyl_nJoDI6XedAGY2kKd_eP-dnsWeccOw2qajd375GRCeiUjqaXv3C7vOkrGEOiSiqfcPQ9y73ROdtl0jJIGemdoYQDd3GcX-dKx6qDwBcPE_qNlqxB0ZTcsDfTwK88OkoVtftMo1zKBWSiZBV9p0GO2erUcSoXtVI-AITDr9jULRDzVL_IzxtPdtuSBrYXMASRi7ex2oKftjJjyG_HMgygf_ULhSYIsHviihCwfx4uO5_zrvh8H84AxAsv33zsFjOaYeZ826JkD3E99hxrAKW3jYr3PjfN-zNZjQLJA/https%3A%2F%2Fwww.mail-archive.com%2Ffreesurfer%40nmr.mgh.harvard.edu%2Fmsg19957.html).
 We have an event-related experiment presenting trait adjectives in terms of 
whether they describe themselves (SELF condition) or someone else (OTHER 
condition). We are interested in testing a 2x2 ANOVA to examine an interaction 
between self-relevance x emotional valence. Assuming you can’t integrate 
individual subject responses to each word in the paradigm file, would we set it 
up as follows?

“Usual” paradigm file:
0              1              2.5          1.0          SELF
2.5          0              2.5          1.0          FIXATION
5.0          1              2.5          1.0          SELF
7.5          2              2.5          1.0          OTHER

Parametric modulation paradigm file:
0              1              2.5          1.0          SELFoffset
0              2              2.5          0.8          SELFslope
0              3              2.5          1.0          VALENCEoffset
0              4              2.5          2.0          VALENCEslope

(where 0.8 reflects the percentage of time the word was endorsed as 
self-relevant and 2.0 is the average valence rating given for that word)

And then create a contrast of 2 vs 4 to test the interaction? Would testing 
contrast 1 vs 0 be a test of the main effect of self-relevance and contrast 3 
vs 0 the main effect of valence?

Thanks so much for your help!
Angela

From: <freesurfer-boun...@nmr.mgh.harvard.edu> on behalf of "Douglas N. Greve" 
<dgr...@mgh.harvard.edu>
Reply-To: Freesurfer support list <freesurfer@nmr.mgh.harvard.edu>
Date: Thursday, July 28, 2022 at 10:25 AM
To: "freesurfer@nmr.mgh.harvard.edu" <freesurfer@nmr.mgh.harvard.edu>
Subject: Re: [Freesurfer] FSFAST first level covariates

Yes, see 
https://secure-web.cisco.com/1vlnv3wLgT6AWyuomHXVnJCfD3bAT8O6KYN-6kv4DVE_Kbs9JwI6WLDqHM7UN7cfJ1TP0eQKgCtR-KXf01ehJnqsV2jW5XmAXQr0QnOlGk4--dT54zncT2aoK1njMKmN9ayqCJ_tFar2vbW-JGXSkTcg6gdUPh_mngiG7m6SxtOvACvAKVHKQXKhe7-xx2QsCh6VDDkv9vQZNEkvMseg2bTElAE9tBG4Nyws1TeLoT6NRejWCSL4Hnke9bOJGLYp7gY561tg-SfXXlzjCNawo6cgCBAIxSsMzwLR8sWZndlid_nZ0aZqf85_HgcVXWUXEoKCbQCJ_Hs2G69KcjGr8yg/https%3A%2F%2Fsurfer.nmr.mgh.harvard.edu%2Ffswiki%2FFsFastParametricModulation
On 7/25/2022 6:56 PM, Angela Fang wrote:

        External Email - Use Caution
Hi Freesurfer community,
I have run participants through an event-related fMRI task in which subjects 
rate whether trait adjectives are descriptive of themselves or not, and 
afterwards asked them to rate each trait word on emotional valence. Is it 
possible to include these individual level subjective ratings of emotional 
valence as covariates in the first level contrast in FSFAST? If so, how?
Thanks,
Angela

---
Angela Fang, Ph.D.
Assistant Professor
Department of Psychology
University of Washington
Lab website: MailScanner has detected a possible fraud attempt from 
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Pronouns: she, her, hers



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