sorry, you lost me there ...

On 8/31/2022 12:39 PM, Angela Fang wrote:

        External Email - Use Caution

That makes sense! And if we wanted to identify brain regions associated with valence (across self/non-self) that is unique from condition 2, can we add a 5^th condition? Maybe we can code self as 2 and non-self as 1 so that condition 2 (self*valence) would be different from condition 5 (valence ratings only)?

Incredibly helpful, Doug- thank you so much!

*From: *<freesurfer-boun...@nmr.mgh.harvard.edu> on behalf of "Douglas N. Greve" <dgr...@mgh.harvard.edu>
*Reply-To: *Freesurfer support list <freesurfer@nmr.mgh.harvard.edu>
*Date: *Tuesday, August 30, 2022 at 7:38 AM
*To: *"freesurfer@nmr.mgh.harvard.edu" <freesurfer@nmr.mgh.harvard.edu>
*Subject: *Re: [Freesurfer] FSFAST first level covariates

Oh, I think I see now. In realty, each trial is either self or not self and then you have a separate valence measure, so your coding should be
1. Self-offset
2. SelfValence
3. NoSelf-offset
4. NoSelfValence

Where 1+2 are used for a self event and 3+4 are used for a noself event. If you want to test for the difference between self and noself valence slope, then you would just use -a 2 -c 4

On 8/29/2022 12:08 PM, Angela Fang wrote:

    *        External Email - Use Caution *

    Great, thanks so much Doug- this setup makes sense to me. However,
    isn’t it a problem that the brain regions associated with the
    contrast for -a 3 and the contrast for -a 4 would be the same for
    trials that subjects rate as 1 (self-relevant) vs 0 (not
    self-relevant)? Could we code it as 2 (self-relevant) and 1 (not
    self-relevant)?

    Many thanks!!

    *From: *<freesurfer-boun...@nmr.mgh.harvard.edu>
    <mailto:freesurfer-boun...@nmr.mgh.harvard.edu> on behalf of
    "Douglas N. Greve" <dgr...@mgh.harvard.edu>
    <mailto:dgr...@mgh.harvard.edu>
    *Reply-To: *Freesurfer support list
    <freesurfer@nmr.mgh.harvard.edu>
    <mailto:freesurfer@nmr.mgh.harvard.edu>
    *Date: *Sunday, August 28, 2022 at 1:07 PM
    *To: *"freesurfer@nmr.mgh.harvard.edu"
    <mailto:freesurfer@nmr.mgh.harvard.edu>
    <freesurfer@nmr.mgh.harvard.edu>
    <mailto:freesurfer@nmr.mgh.harvard.edu>
    *Subject: *Re: [Freesurfer] FSFAST first level covariates

    I was under the impression that Self and Valence were ratings from
    the same event (in that mail archive, they were different events
    and so needed different offsets). If Self and Valence are from the
    same event, then you would have something like
    1. Offset
    2. Self
    3. Valence
    4. Self*Valence
    I've never tried the interaction (self*valence). You might have to
    demean before computing the product

    On 8/14/2022 4:58 PM, Angela Fang wrote:

        *        External Email - Use Caution *

        The two coding schemes are different because the second one
        does include the self*valence variable you’re talking about,
        whereas the first one doesn’t. I only included the 2^nd offset
        because you suggested to someone else to include it (see
        *MailScanner has detected a possible fraud attempt from
        "secure-web.cisco.com" claiming to be*
        
https://www.mail-archive.com/freesurfer@nmr.mgh.harvard.edu/msg19957.html
        
<https://secure-web.cisco.com/1UvSz7SvjZnlE1QfkdS-VBc1GzXeZMYqUcsOqE3dGoo43anjoKIpvfs4NnozgTlCx23dB10wC_oFWTi8Zyazh1v1oufO7QQBf9hJanKAiwbu0cr4NfMvGMSOSaaOt5nSATHi-J-55MTqcCUhjz8_rRM1YuYWhtxzDVrlNJ5mD3QlEmdQlhRlYoneii_5mWjAZB1gcbpR_0Zl1nUaCy9BfmpcQRNLpIdfE1NMjg7OnqHOX5jAdPz1gGqxVTKgstTqx8RhxmTkDYOQPLc6hC3by-Atu2VfBnloD3GbZOzG04LjV1Of0uYaB6pk6oSsZFULTsifcwPSiwh1m9gKSg5lD7Q/https%3A%2F%2Fwww.mail-archive.com%2Ffreesurfer%40nmr.mgh.harvard.edu%2Fmsg19957.html>).
        If we don’t need it, would it just be 2 conditions, as follows?

         1. SelfOffset
         2. Self*ValenceSlope

        But then I’m not clear how to get the main effect of valence
        (brain regions that scale with increasing emotion valence,
        while holding self-relevance constant)?

        *From: *<freesurfer-boun...@nmr.mgh.harvard.edu>
        <mailto:freesurfer-boun...@nmr.mgh.harvard.edu> on behalf of
        "Douglas N. Greve" <dgr...@mgh.harvard.edu>
        <mailto:dgr...@mgh.harvard.edu>
        *Reply-To: *Freesurfer support list
        <freesurfer@nmr.mgh.harvard.edu>
        <mailto:freesurfer@nmr.mgh.harvard.edu>
        *Date: *Sunday, August 14, 2022 at 1:37 PM
        *To: *"freesurfer@nmr.mgh.harvard.edu"
        <mailto:freesurfer@nmr.mgh.harvard.edu>
        <freesurfer@nmr.mgh.harvard.edu>
        <mailto:freesurfer@nmr.mgh.harvard.edu>
        *Subject: *Re: [Freesurfer] FSFAST first level covariates

        Those look like they are the same coding scheme. What is
        different? You can only have one offset. The Self vs Valence
        -a 2 -a 4 is not testing for an interaction. If you want an
        interaction you have to create a new variable which is
        SelfRating*ValenceRating.

        On 8/10/2022 2:38 PM, Angela Fang wrote:

            *        External Email - Use Caution *

            Hello,

            Just re-sending my question below. If I have a variable
            with 2 levels (yes/no) and another variable that is
            continuous, based on this post (*MailScanner has detected
            a possible fraud attempt from "secure-web.cisco.com"
            claiming to be*
            
https://www.mail-archive.com/freesurfer@nmr.mgh.harvard.edu/msg19957.html
            
<https://secure-web.cisco.com/1S2s08xk6_r2FFsEB5S1KdOcfq6G8ToJwyZuNFONdwgOYd87JJkB-uznJW2pelg24KQwX3lweVOmFs99TCKitjbJOqKWgEH_UW7wir5JQ113csODerDntanBrEibOdt6Mxs2QeQ5D7n69Ds6NaOSOJIbLFeMjuoaTXCkNccNydn7jvjmVd0zW2YhEXG9JtLxMNVIYt8q48ZK0sJUt8sjTP6xuCzA1pzB19MUHA078Zgygtns0YVgn1n5Sg41ZbVZ3jWciX5ZF34AejW5nWj1Z4mWO1Xyd_7RwNbKkVMPeDwG6K9W59gzBf_t0G-AzmUhxGC8zfKM0bxA9hhZv4GR2BQ/https%3A%2F%2Fwww.mail-archive.com%2Ffreesurfer%40nmr.mgh.harvard.edu%2Fmsg19957.html>),
            it sounds like I should code as follows:

             1. SelfOffset
             2. Self-ValenceSlope (would the weight in the 4^th column
                reflect the value of self multiplied by the value of
                valence for this participant?)
             3. NonSelfOffset
             4. NonSelf-ValenceSlope

            If the other way of modifying the paradigm file is also
            acceptable to test the interaction (as I describe below),
            that would also be helpful to know.

            Thanks!

            Angela

            *From: *<freesurfer-boun...@nmr.mgh.harvard.edu>
            <mailto:freesurfer-boun...@nmr.mgh.harvard.edu> on behalf
            of Angela Fang <angf...@uw.edu> <mailto:angf...@uw.edu>
            *Reply-To: *Freesurfer support list
            <freesurfer@nmr.mgh.harvard.edu>
            <mailto:freesurfer@nmr.mgh.harvard.edu>
            *Date: *Monday, August 1, 2022 at 4:35 PM
            *To: *Freesurfer support list
            <freesurfer@nmr.mgh.harvard.edu>
            <mailto:freesurfer@nmr.mgh.harvard.edu>
            *Subject: *Re: [Freesurfer] FSFAST first level covariates

            *        External Email - Use Caution *

            Hi Doug,

            Nevermind to my first question! I read this post
            (*MailScanner has detected a possible fraud attempt from
            "secure-web.cisco.com" claiming to be*
            
https://www.mail-archive.com/freesurfer@nmr.mgh.harvard.edu/msg32235.html
            
<https://secure-web.cisco.com/1646ymi0_yM9ab72e81bZdCKw_zNbXr9RihxDaiDVPq0_Qd4EXYgDmO56zQdi9l_AyV3uyyiURXHoYWQmiu56CbMuIGdZz8EH0gbsnVrAz9KwunZAwLzh0kh-jzVwHtlbEdd1ExEJYHT7o7JtUWg2GM484JTyL0VZJymRuGRyD0ag1nQ_0BPPjQHxPCqNHEU4Y_seBsq9XsUROgyR-bX-tHVXxhshVUHgneudw6tEB2lIVYfYrL3srRbjy1QN9Bq_e3_WaNCDhkXdixnae24i41HHYwJfn3KwsmNoZ2RxLoh3SMkXXwVntAewl8PeldBY0s3UxoEPiFbDdXXuJLUjlw/https%3A%2F%2Fwww.mail-archive.com%2Ffreesurfer%40nmr.mgh.harvard.edu%2Fmsg32235.html>)
            and realized that we always include a subject-specific par
            file in each run for first-level analyses.

            However, I’m still confused about how to modify my
            paradigm file. I also need to model the trials of
            non-interest, so would it be as follows?

            0 1              2.5          1.0          SelfOffset

            0 2              2.5          1.0          SelfSlope
            (equal to subject’s rating of self-relevance)

            0 3              2.5          1.0          ValenceOffset

            0 4              2.5          3.0 ValenceSlope (equal to
            subject’s rating of valence)

            2.5 0              2.5          1.0          FIXATION

            5.0 1              2.5          1.0          SelfOffset

            5.0 2              2.5          0              SelfSlope
            (equal to subject’s rating of self-relevance, in this case
            subject responded 0, or non-relevant)

            5.0 3              2.5          1.0          ValenceOffset

            5.0 4              2.5          2.0          ValenceSlope
            (equal to subject’s rating of valence)

            7.5 5              2.5          1.0          OTHER

            Do these contrasts look correct to you?

            Self vs Fixation -a 1 -c 0 (main effect of self)

            Valence vs Fixation -a 3 -c 0 (main effect of valence)

            Self vs Valence -a 2 -a 4 (interaction between self x valence)

            Thank you so much for your help!

            Angela

            *From: *<freesurfer-boun...@nmr.mgh.harvard.edu>
            <mailto:freesurfer-boun...@nmr.mgh.harvard.edu> on behalf
            of Angela Fang <angf...@uw.edu> <mailto:angf...@uw.edu>
            *Reply-To: *Freesurfer support list
            <freesurfer@nmr.mgh.harvard.edu>
            <mailto:freesurfer@nmr.mgh.harvard.edu>
            *Date: *Thursday, July 28, 2022 at 1:02 PM
            *To: *Freesurfer support list
            <freesurfer@nmr.mgh.harvard.edu>
            <mailto:freesurfer@nmr.mgh.harvard.edu>
            *Subject: *Re: [Freesurfer] FSFAST first level covariates

            Thanks Doug. This wiki page is extremely helpful. However,
            my question is about individual subject responses. I could
            see how you could include a summary (e.g., average) value
            of the parametric variable across subjects in your
            “weight” column but it’s not clear to me how you could
            integrate individual subject responses to each word in the
            parametric modulation paradigm file? I’m imagining
            something like the FSGD file where a value is given for
            each subject, but for first-level analysis.

            We have a similar design as someone else who posted a
            similar question (*MailScanner has detected a possible
            fraud attempt from "secure-web.cisco.com" claiming to be*
            
https://www.mail-archive.com/freesurfer@nmr.mgh.harvard.edu/msg19957.html
            
<https://secure-web.cisco.com/11nFbIrJYBqRI1W_4wY-HvfdEF3GG6xLL8So8t0i9yKbcElVyl_nJoDI6XedAGY2kKd_eP-dnsWeccOw2qajd375GRCeiUjqaXv3C7vOkrGEOiSiqfcPQ9y73ROdtl0jJIGemdoYQDd3GcX-dKx6qDwBcPE_qNlqxB0ZTcsDfTwK88OkoVtftMo1zKBWSiZBV9p0GO2erUcSoXtVI-AITDr9jULRDzVL_IzxtPdtuSBrYXMASRi7ex2oKftjJjyG_HMgygf_ULhSYIsHviihCwfx4uO5_zrvh8H84AxAsv33zsFjOaYeZ826JkD3E99hxrAKW3jYr3PjfN-zNZjQLJA/https%3A%2F%2Fwww.mail-archive.com%2Ffreesurfer%40nmr.mgh.harvard.edu%2Fmsg19957.html>).
            We have an event-related experiment presenting trait
            adjectives in terms of whether they describe themselves
            (SELF condition) or someone else (OTHER condition). We are
            interested in testing a 2x2 ANOVA to examine an
            interaction between self-relevance x emotional valence.
            Assuming you can’t integrate individual subject responses
            to each word in the paradigm file, would we set it up as
            follows?

            “Usual” paradigm file:

            0 1              2.5          1.0          SELF

            2.5 0              2.5          1.0          FIXATION

            5.0 1              2.5          1.0          SELF

            7.5 2              2.5          1.0          OTHER

            Parametric modulation paradigm file:

            0 1              2.5          1.0          SELFoffset

            0 2              2.5          0.8          SELFslope

            0 3              2.5          1.0          VALENCEoffset

            0 4              2.5          2.0          VALENCEslope

            (where 0.8 reflects the percentage of time the word was
            endorsed as self-relevant and 2.0 is the average valence
            rating given for that word)

            And then create a contrast of 2 vs 4 to test the
            interaction? Would testing contrast 1 vs 0 be a test of
            the main effect of self-relevance and contrast 3 vs 0 the
            main effect of valence?

            Thanks so much for your help!

            Angela

            *From: *<freesurfer-boun...@nmr.mgh.harvard.edu>
            <mailto:freesurfer-boun...@nmr.mgh.harvard.edu> on behalf
            of "Douglas N. Greve" <dgr...@mgh.harvard.edu>
            <mailto:dgr...@mgh.harvard.edu>
            *Reply-To: *Freesurfer support list
            <freesurfer@nmr.mgh.harvard.edu>
            <mailto:freesurfer@nmr.mgh.harvard.edu>
            *Date: *Thursday, July 28, 2022 at 10:25 AM
            *To: *"freesurfer@nmr.mgh.harvard.edu"
            <mailto:freesurfer@nmr.mgh.harvard.edu>
            <freesurfer@nmr.mgh.harvard.edu>
            <mailto:freesurfer@nmr.mgh.harvard.edu>
            *Subject: *Re: [Freesurfer] FSFAST first level covariates

            Yes, see *MailScanner has detected a possible fraud
            attempt from "secure-web.cisco.com" claiming to be*
            https://surfer.nmr.mgh.harvard.edu/fswiki/FsFastParametricModulation
            
<https://secure-web.cisco.com/1vlnv3wLgT6AWyuomHXVnJCfD3bAT8O6KYN-6kv4DVE_Kbs9JwI6WLDqHM7UN7cfJ1TP0eQKgCtR-KXf01ehJnqsV2jW5XmAXQr0QnOlGk4--dT54zncT2aoK1njMKmN9ayqCJ_tFar2vbW-JGXSkTcg6gdUPh_mngiG7m6SxtOvACvAKVHKQXKhe7-xx2QsCh6VDDkv9vQZNEkvMseg2bTElAE9tBG4Nyws1TeLoT6NRejWCSL4Hnke9bOJGLYp7gY561tg-SfXXlzjCNawo6cgCBAIxSsMzwLR8sWZndlid_nZ0aZqf85_HgcVXWUXEoKCbQCJ_Hs2G69KcjGr8yg/https%3A%2F%2Fsurfer.nmr.mgh.harvard.edu%2Ffswiki%2FFsFastParametricModulation>

            On 7/25/2022 6:56 PM, Angela Fang wrote:

                *        External Email - Use Caution *

                Hi Freesurfer community,

                I have run participants through an event-related fMRI
                task in which subjects rate whether trait adjectives
                are descriptive of themselves or not, and afterwards
                asked them to rate each trait word on emotional
                valence. Is it possible to include these individual
                level subjective ratings of emotional valence as
                covariates in the first level contrast in FSFAST? If
                so, how?

                Thanks,

                Angela

                ---

                Angela Fang, Ph.D.

                Assistant Professor
                Department of Psychology

                University of Washington

                Lab website: *MailScanner has detected a possible
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                Pronouns: she, her, hers

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