External Email - Use Caution        

That makes sense! And if we wanted to identify brain regions associated with 
valence (across self/non-self) that is unique from condition 2, can we add a 
5th condition? Maybe we can code self as 2 and non-self as 1 so that condition 
2 (self*valence) would be different from condition 5 (valence ratings only)?

Incredibly helpful, Doug- thank you so much!

From: <freesurfer-boun...@nmr.mgh.harvard.edu> on behalf of "Douglas N. Greve" 
<dgr...@mgh.harvard.edu>
Reply-To: Freesurfer support list <freesurfer@nmr.mgh.harvard.edu>
Date: Tuesday, August 30, 2022 at 7:38 AM
To: "freesurfer@nmr.mgh.harvard.edu" <freesurfer@nmr.mgh.harvard.edu>
Subject: Re: [Freesurfer] FSFAST first level covariates

Oh, I think I see now. In realty, each trial is either self or not self and 
then you have a separate valence measure, so your coding should be
1. Self-offset
2. SelfValence
3. NoSelf-offset
4. NoSelfValence

Where 1+2 are used for a self event and 3+4 are used for a noself event. If you 
want to test for the difference between self and noself valence slope, then you 
would just use -a 2 -c 4

On 8/29/2022 12:08 PM, Angela Fang wrote:

        External Email - Use Caution
Great, thanks so much Doug- this setup makes sense to me. However, isn’t it a 
problem that the brain regions associated with the contrast for -a 3 and the 
contrast for -a 4 would be the same for trials that subjects rate as 1 
(self-relevant) vs 0 (not self-relevant)? Could we code it as 2 (self-relevant) 
and 1 (not self-relevant)?

Many thanks!!

From: 
<freesurfer-boun...@nmr.mgh.harvard.edu><mailto:freesurfer-boun...@nmr.mgh.harvard.edu>
 on behalf of "Douglas N. Greve" 
<dgr...@mgh.harvard.edu><mailto:dgr...@mgh.harvard.edu>
Reply-To: Freesurfer support list 
<freesurfer@nmr.mgh.harvard.edu><mailto:freesurfer@nmr.mgh.harvard.edu>
Date: Sunday, August 28, 2022 at 1:07 PM
To: "freesurfer@nmr.mgh.harvard.edu"<mailto:freesurfer@nmr.mgh.harvard.edu> 
<freesurfer@nmr.mgh.harvard.edu><mailto:freesurfer@nmr.mgh.harvard.edu>
Subject: Re: [Freesurfer] FSFAST first level covariates

I was under the impression that Self and Valence were ratings from the same 
event (in that mail archive, they were different events and so needed different 
offsets). If Self and Valence are from the same event, then you would have 
something like
1. Offset
2. Self
3. Valence
4. Self*Valence
I've never tried the interaction (self*valence). You might have to demean 
before computing the product
On 8/14/2022 4:58 PM, Angela Fang wrote:

        External Email - Use Caution
The two coding schemes are different because the second one does include the 
self*valence variable you’re talking about, whereas the first one doesn’t. I 
only included the 2nd offset because you suggested to someone else to include 
it (see MailScanner has detected a possible fraud attempt from 
"secure-web.cisco.com" claiming to be 
https://secure-web.cisco.com/1axFb8Uk3EidN7RU3PxCMFcOtbS8C3cmNULxUDXhNgudqc2v-5LUyAYUUUC6m-FcwrPwdVKy2Y7n8DAVcyRmfV5k4NWvno0aemc07RzaIinRQ8-6_FFiXeiHdOzhbARiwJyY4xdCGKBBbKJGuolxWhUQ5ZaDv2NtX0TJ7BmyhFTGOFw4S9sp6o7il_xApboosWIOBOJb1zh7hBwMks3eFrd04OkImYWLahgGjjS7Zs4BjsQy1dYPiBCXK_vv2cHadYnHraA451p-pjerGjuvaFs9cp4jm03dcia0ilLlFFYK5n74UApp-Da_ShPd4EN_o7az4F96Vwm7OtA1A2eemJw/https%3A%2F%2Fwww.mail-archive.com%2Ffreesurfer%40nmr.mgh.harvard.edu%2Fmsg19957.html<https://secure-web.cisco.com/1UvSz7SvjZnlE1QfkdS-VBc1GzXeZMYqUcsOqE3dGoo43anjoKIpvfs4NnozgTlCx23dB10wC_oFWTi8Zyazh1v1oufO7QQBf9hJanKAiwbu0cr4NfMvGMSOSaaOt5nSATHi-J-55MTqcCUhjz8_rRM1YuYWhtxzDVrlNJ5mD3QlEmdQlhRlYoneii_5mWjAZB1gcbpR_0Zl1nUaCy9BfmpcQRNLpIdfE1NMjg7OnqHOX5jAdPz1gGqxVTKgstTqx8RhxmTkDYOQPLc6hC3by-Atu2VfBnloD3GbZOzG04LjV1Of0uYaB6pk6oSsZFULTsifcwPSiwh1m9gKSg5lD7Q/https%3A%2F%2Fwww.mail-archive.com%2Ffreesurfer%40nmr.mgh.harvard.edu%2Fmsg19957.html>).
 If we don’t need it, would it just be 2 conditions, as follows?


  1.  SelfOffset
  2.  Self*ValenceSlope

But then I’m not clear how to get the main effect of valence (brain regions 
that scale with increasing emotion valence, while holding self-relevance 
constant)?

From: 
<freesurfer-boun...@nmr.mgh.harvard.edu><mailto:freesurfer-boun...@nmr.mgh.harvard.edu>
 on behalf of "Douglas N. Greve" 
<dgr...@mgh.harvard.edu><mailto:dgr...@mgh.harvard.edu>
Reply-To: Freesurfer support list 
<freesurfer@nmr.mgh.harvard.edu><mailto:freesurfer@nmr.mgh.harvard.edu>
Date: Sunday, August 14, 2022 at 1:37 PM
To: "freesurfer@nmr.mgh.harvard.edu"<mailto:freesurfer@nmr.mgh.harvard.edu> 
<freesurfer@nmr.mgh.harvard.edu><mailto:freesurfer@nmr.mgh.harvard.edu>
Subject: Re: [Freesurfer] FSFAST first level covariates

Those look like they are the same coding scheme. What is different? You can 
only have one offset. The Self vs Valence -a 2 -a 4 is not testing for an 
interaction. If you want an interaction you have to create a new variable which 
is SelfRating*ValenceRating.

On 8/10/2022 2:38 PM, Angela Fang wrote:

        External Email - Use Caution
Hello,

Just re-sending my question below. If I have a variable with 2 levels (yes/no) 
and another variable that is continuous, based on this post (MailScanner has 
detected a possible fraud attempt from "secure-web.cisco.com" claiming to be 
https://secure-web.cisco.com/1axFb8Uk3EidN7RU3PxCMFcOtbS8C3cmNULxUDXhNgudqc2v-5LUyAYUUUC6m-FcwrPwdVKy2Y7n8DAVcyRmfV5k4NWvno0aemc07RzaIinRQ8-6_FFiXeiHdOzhbARiwJyY4xdCGKBBbKJGuolxWhUQ5ZaDv2NtX0TJ7BmyhFTGOFw4S9sp6o7il_xApboosWIOBOJb1zh7hBwMks3eFrd04OkImYWLahgGjjS7Zs4BjsQy1dYPiBCXK_vv2cHadYnHraA451p-pjerGjuvaFs9cp4jm03dcia0ilLlFFYK5n74UApp-Da_ShPd4EN_o7az4F96Vwm7OtA1A2eemJw/https%3A%2F%2Fwww.mail-archive.com%2Ffreesurfer%40nmr.mgh.harvard.edu%2Fmsg19957.html<https://secure-web.cisco.com/1S2s08xk6_r2FFsEB5S1KdOcfq6G8ToJwyZuNFONdwgOYd87JJkB-uznJW2pelg24KQwX3lweVOmFs99TCKitjbJOqKWgEH_UW7wir5JQ113csODerDntanBrEibOdt6Mxs2QeQ5D7n69Ds6NaOSOJIbLFeMjuoaTXCkNccNydn7jvjmVd0zW2YhEXG9JtLxMNVIYt8q48ZK0sJUt8sjTP6xuCzA1pzB19MUHA078Zgygtns0YVgn1n5Sg41ZbVZ3jWciX5ZF34AejW5nWj1Z4mWO1Xyd_7RwNbKkVMPeDwG6K9W59gzBf_t0G-AzmUhxGC8zfKM0bxA9hhZv4GR2BQ/https%3A%2F%2Fwww.mail-archive.com%2Ffreesurfer%40nmr.mgh.harvard.edu%2Fmsg19957.html>),
 it sounds like I should code as follows:


  1.  SelfOffset
  2.  Self-ValenceSlope (would the weight in the 4th column reflect the value 
of self multiplied by the value of valence for this participant?)
  3.  NonSelfOffset
  4.  NonSelf-ValenceSlope

If the other way of modifying the paradigm file is also acceptable to test the 
interaction (as I describe below), that would also be helpful to know.

Thanks!
Angela

From: 
<freesurfer-boun...@nmr.mgh.harvard.edu><mailto:freesurfer-boun...@nmr.mgh.harvard.edu>
 on behalf of Angela Fang <angf...@uw.edu><mailto:angf...@uw.edu>
Reply-To: Freesurfer support list 
<freesurfer@nmr.mgh.harvard.edu><mailto:freesurfer@nmr.mgh.harvard.edu>
Date: Monday, August 1, 2022 at 4:35 PM
To: Freesurfer support list 
<freesurfer@nmr.mgh.harvard.edu><mailto:freesurfer@nmr.mgh.harvard.edu>
Subject: Re: [Freesurfer] FSFAST first level covariates


        External Email - Use Caution
Hi Doug,

Nevermind to my first question! I read this post (MailScanner has detected a 
possible fraud attempt from "secure-web.cisco.com" claiming to be 
https://secure-web.cisco.com/1x486JnVcuVKZFlKc9lnM17mkutiyvGdWJ7I2FV8fwW_DW3coauzdEYjTthPWCuUI49R8eR7JdFGVDEm-PGd9Gp03GX15R1fQSmiF_Oa0GSUysb9oU2BILoHtXNRTr2wYopYLEgZzR0uHoS42fJD6Y6OgxNPab4zkRakvC9SczCpOmDIjix_3coBjxNyEGBZxGeQ43psRUWNXcOqObLo5i75Sk5As8_8hlVX0lY3Nhlg6GpZxPNxznyC2k4HTCODw-faGH-b0xy25IwE7YN7YmWgVADwyzJ3Ra2p48FjTCCD90Yn7ggECXgkApxbdwYhEozkxSvgygst9PXkZBXgH3g/https%3A%2F%2Fwww.mail-archive.com%2Ffreesurfer%40nmr.mgh.harvard.edu%2Fmsg32235.html<https://secure-web.cisco.com/1646ymi0_yM9ab72e81bZdCKw_zNbXr9RihxDaiDVPq0_Qd4EXYgDmO56zQdi9l_AyV3uyyiURXHoYWQmiu56CbMuIGdZz8EH0gbsnVrAz9KwunZAwLzh0kh-jzVwHtlbEdd1ExEJYHT7o7JtUWg2GM484JTyL0VZJymRuGRyD0ag1nQ_0BPPjQHxPCqNHEU4Y_seBsq9XsUROgyR-bX-tHVXxhshVUHgneudw6tEB2lIVYfYrL3srRbjy1QN9Bq_e3_WaNCDhkXdixnae24i41HHYwJfn3KwsmNoZ2RxLoh3SMkXXwVntAewl8PeldBY0s3UxoEPiFbDdXXuJLUjlw/https%3A%2F%2Fwww.mail-archive.com%2Ffreesurfer%40nmr.mgh.harvard.edu%2Fmsg32235.html>)
 and realized that we always include a subject-specific par file in each run 
for first-level analyses.

However, I’m still confused about how to modify my paradigm file. I also need 
to model the trials of non-interest, so would it be as follows?

0             1              2.5          1.0          SelfOffset
0              2              2.5          1.0          SelfSlope (equal to 
subject’s rating of self-relevance)
0              3              2.5          1.0          ValenceOffset
0              4              2.5          3.0          ValenceSlope (equal to 
subject’s rating of valence)

2.5          0              2.5          1.0          FIXATION

5.0          1              2.5          1.0          SelfOffset
5.0          2              2.5          0              SelfSlope (equal to 
subject’s rating of self-relevance, in this case subject responded 0, or 
non-relevant)
5.0          3              2.5          1.0          ValenceOffset
5.0          4              2.5          2.0          ValenceSlope (equal to 
subject’s rating of valence)

7.5          5              2.5          1.0          OTHER

Do these contrasts look correct to you?
Self vs Fixation -a 1 -c 0 (main effect of self)
Valence vs Fixation -a 3 -c 0 (main effect of valence)
Self vs Valence -a 2 -a 4 (interaction between self x valence)

Thank you so much for your help!
Angela

From: 
<freesurfer-boun...@nmr.mgh.harvard.edu><mailto:freesurfer-boun...@nmr.mgh.harvard.edu>
 on behalf of Angela Fang <angf...@uw.edu><mailto:angf...@uw.edu>
Reply-To: Freesurfer support list 
<freesurfer@nmr.mgh.harvard.edu><mailto:freesurfer@nmr.mgh.harvard.edu>
Date: Thursday, July 28, 2022 at 1:02 PM
To: Freesurfer support list 
<freesurfer@nmr.mgh.harvard.edu><mailto:freesurfer@nmr.mgh.harvard.edu>
Subject: Re: [Freesurfer] FSFAST first level covariates

Thanks Doug. This wiki page is extremely helpful. However, my question is about 
individual subject responses. I could see how you could include a summary 
(e.g., average) value of the parametric variable across subjects in your 
“weight” column but it’s not clear to me how you could integrate individual 
subject responses to each word in the parametric modulation paradigm file? I’m 
imagining something like the FSGD file where a value is given for each subject, 
but for first-level analysis.

We have a similar design as someone else who posted a similar question 
(MailScanner has detected a possible fraud attempt from "secure-web.cisco.com" 
claiming to be 
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 We have an event-related experiment presenting trait adjectives in terms of 
whether they describe themselves (SELF condition) or someone else (OTHER 
condition). We are interested in testing a 2x2 ANOVA to examine an interaction 
between self-relevance x emotional valence. Assuming you can’t integrate 
individual subject responses to each word in the paradigm file, would we set it 
up as follows?

“Usual” paradigm file:
0              1              2.5          1.0          SELF
2.5          0              2.5          1.0          FIXATION
5.0          1              2.5          1.0          SELF
7.5          2              2.5          1.0          OTHER

Parametric modulation paradigm file:
0              1              2.5          1.0          SELFoffset
0              2              2.5          0.8          SELFslope
0              3              2.5          1.0          VALENCEoffset
0              4              2.5          2.0          VALENCEslope

(where 0.8 reflects the percentage of time the word was endorsed as 
self-relevant and 2.0 is the average valence rating given for that word)

And then create a contrast of 2 vs 4 to test the interaction? Would testing 
contrast 1 vs 0 be a test of the main effect of self-relevance and contrast 3 
vs 0 the main effect of valence?

Thanks so much for your help!
Angela

From: 
<freesurfer-boun...@nmr.mgh.harvard.edu><mailto:freesurfer-boun...@nmr.mgh.harvard.edu>
 on behalf of "Douglas N. Greve" 
<dgr...@mgh.harvard.edu><mailto:dgr...@mgh.harvard.edu>
Reply-To: Freesurfer support list 
<freesurfer@nmr.mgh.harvard.edu><mailto:freesurfer@nmr.mgh.harvard.edu>
Date: Thursday, July 28, 2022 at 10:25 AM
To: "freesurfer@nmr.mgh.harvard.edu"<mailto:freesurfer@nmr.mgh.harvard.edu> 
<freesurfer@nmr.mgh.harvard.edu><mailto:freesurfer@nmr.mgh.harvard.edu>
Subject: Re: [Freesurfer] FSFAST first level covariates

Yes, see MailScanner has detected a possible fraud attempt from 
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On 7/25/2022 6:56 PM, Angela Fang wrote:

        External Email - Use Caution
Hi Freesurfer community,
I have run participants through an event-related fMRI task in which subjects 
rate whether trait adjectives are descriptive of themselves or not, and 
afterwards asked them to rate each trait word on emotional valence. Is it 
possible to include these individual level subjective ratings of emotional 
valence as covariates in the first level contrast in FSFAST? If so, how?
Thanks,
Angela

---
Angela Fang, Ph.D.
Assistant Professor
Department of Psychology
University of Washington
Lab website: MailScanner has detected a possible fraud attempt from 
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Pronouns: she, her, hers



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MailScanner has detected a possible fraud attempt from "secure-web.cisco.com" 
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