Those look like they are the same coding scheme. What is different? You can only have one offset. The Self vs Valence -a 2 -a 4 is not testing for an interaction. If you want an interaction you have to create a new variable which is SelfRating*ValenceRating.

On 8/10/2022 2:38 PM, Angela Fang wrote:

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Hello,

Just re-sending my question below. If I have a variable with 2 levels (yes/no) and another variable that is continuous, based on this post (*MailScanner has detected a possible fraud attempt from "secure-web.cisco.com" claiming to be* https://www.mail-archive.com/freesurfer@nmr.mgh.harvard.edu/msg19957.html <https://secure-web.cisco.com/1S2s08xk6_r2FFsEB5S1KdOcfq6G8ToJwyZuNFONdwgOYd87JJkB-uznJW2pelg24KQwX3lweVOmFs99TCKitjbJOqKWgEH_UW7wir5JQ113csODerDntanBrEibOdt6Mxs2QeQ5D7n69Ds6NaOSOJIbLFeMjuoaTXCkNccNydn7jvjmVd0zW2YhEXG9JtLxMNVIYt8q48ZK0sJUt8sjTP6xuCzA1pzB19MUHA078Zgygtns0YVgn1n5Sg41ZbVZ3jWciX5ZF34AejW5nWj1Z4mWO1Xyd_7RwNbKkVMPeDwG6K9W59gzBf_t0G-AzmUhxGC8zfKM0bxA9hhZv4GR2BQ/https%3A%2F%2Fwww.mail-archive.com%2Ffreesurfer%40nmr.mgh.harvard.edu%2Fmsg19957.html>), it sounds like I should code as follows:

 1. SelfOffset
 2. Self-ValenceSlope (would the weight in the 4^th column reflect the
    value of self multiplied by the value of valence for this
    participant?)
 3. NonSelfOffset
 4. NonSelf-ValenceSlope

If the other way of modifying the paradigm file is also acceptable to test the interaction (as I describe below), that would also be helpful to know.

Thanks!

Angela

*From: *<freesurfer-boun...@nmr.mgh.harvard.edu> on behalf of Angela Fang <angf...@uw.edu>
*Reply-To: *Freesurfer support list <freesurfer@nmr.mgh.harvard.edu>
*Date: *Monday, August 1, 2022 at 4:35 PM
*To: *Freesurfer support list <freesurfer@nmr.mgh.harvard.edu>
*Subject: *Re: [Freesurfer] FSFAST first level covariates

*        External Email - Use Caution *

Hi Doug,

Nevermind to my first question! I read this post (*MailScanner has detected a possible fraud attempt from "secure-web.cisco.com" claiming to be* https://www.mail-archive.com/freesurfer@nmr.mgh.harvard.edu/msg32235.html <https://secure-web.cisco.com/1646ymi0_yM9ab72e81bZdCKw_zNbXr9RihxDaiDVPq0_Qd4EXYgDmO56zQdi9l_AyV3uyyiURXHoYWQmiu56CbMuIGdZz8EH0gbsnVrAz9KwunZAwLzh0kh-jzVwHtlbEdd1ExEJYHT7o7JtUWg2GM484JTyL0VZJymRuGRyD0ag1nQ_0BPPjQHxPCqNHEU4Y_seBsq9XsUROgyR-bX-tHVXxhshVUHgneudw6tEB2lIVYfYrL3srRbjy1QN9Bq_e3_WaNCDhkXdixnae24i41HHYwJfn3KwsmNoZ2RxLoh3SMkXXwVntAewl8PeldBY0s3UxoEPiFbDdXXuJLUjlw/https%3A%2F%2Fwww.mail-archive.com%2Ffreesurfer%40nmr.mgh.harvard.edu%2Fmsg32235.html>) and realized that we always include a subject-specific par file in each run for first-level analyses.

However, I’m still confused about how to modify my paradigm file. I also need to model the trials of non-interest, so would it be as follows?

0 1              2.5          1.0          SelfOffset

0 2              2.5          1.0          SelfSlope (equal to subject’s rating of self-relevance)

0 3              2.5          1.0          ValenceOffset

0 4              2.5          3.0          ValenceSlope (equal to subject’s rating of valence)

2.5 0              2.5          1.0          FIXATION

5.0 1              2.5          1.0          SelfOffset

5.0 2              2.5          0              SelfSlope (equal to subject’s rating of self-relevance, in this case subject responded 0, or non-relevant)

5.0 3              2.5          1.0          ValenceOffset

5.0 4              2.5          2.0          ValenceSlope (equal to subject’s rating of valence)

7.5 5              2.5          1.0          OTHER

Do these contrasts look correct to you?

Self vs Fixation -a 1 -c 0 (main effect of self)

Valence vs Fixation -a 3 -c 0 (main effect of valence)

Self vs Valence -a 2 -a 4 (interaction between self x valence)

Thank you so much for your help!

Angela

*From: *<freesurfer-boun...@nmr.mgh.harvard.edu> on behalf of Angela Fang <angf...@uw.edu>
*Reply-To: *Freesurfer support list <freesurfer@nmr.mgh.harvard.edu>
*Date: *Thursday, July 28, 2022 at 1:02 PM
*To: *Freesurfer support list <freesurfer@nmr.mgh.harvard.edu>
*Subject: *Re: [Freesurfer] FSFAST first level covariates

Thanks Doug. This wiki page is extremely helpful. However, my question is about individual subject responses. I could see how you could include a summary (e.g., average) value of the parametric variable across subjects in your “weight” column but it’s not clear to me how you could integrate individual subject responses to each word in the parametric modulation paradigm file? I’m imagining something like the FSGD file where a value is given for each subject, but for first-level analysis.

We have a similar design as someone else who posted a similar question (*MailScanner has detected a possible fraud attempt from "secure-web.cisco.com" claiming to be* https://www.mail-archive.com/freesurfer@nmr.mgh.harvard.edu/msg19957.html <https://secure-web.cisco.com/11nFbIrJYBqRI1W_4wY-HvfdEF3GG6xLL8So8t0i9yKbcElVyl_nJoDI6XedAGY2kKd_eP-dnsWeccOw2qajd375GRCeiUjqaXv3C7vOkrGEOiSiqfcPQ9y73ROdtl0jJIGemdoYQDd3GcX-dKx6qDwBcPE_qNlqxB0ZTcsDfTwK88OkoVtftMo1zKBWSiZBV9p0GO2erUcSoXtVI-AITDr9jULRDzVL_IzxtPdtuSBrYXMASRi7ex2oKftjJjyG_HMgygf_ULhSYIsHviihCwfx4uO5_zrvh8H84AxAsv33zsFjOaYeZ826JkD3E99hxrAKW3jYr3PjfN-zNZjQLJA/https%3A%2F%2Fwww.mail-archive.com%2Ffreesurfer%40nmr.mgh.harvard.edu%2Fmsg19957.html>). We have an event-related experiment presenting trait adjectives in terms of whether they describe themselves (SELF condition) or someone else (OTHER condition). We are interested in testing a 2x2 ANOVA to examine an interaction between self-relevance x emotional valence. Assuming you can’t integrate individual subject responses to each word in the paradigm file, would we set it up as follows?

“Usual” paradigm file:

0 1              2.5          1.0          SELF

2.5 0              2.5          1.0          FIXATION

5.0 1              2.5          1.0          SELF

7.5 2              2.5          1.0          OTHER

Parametric modulation paradigm file:

0 1              2.5          1.0          SELFoffset

0 2              2.5          0.8          SELFslope

0 3              2.5          1.0          VALENCEoffset

0 4              2.5          2.0          VALENCEslope

(where 0.8 reflects the percentage of time the word was endorsed as self-relevant and 2.0 is the average valence rating given for that word)

And then create a contrast of 2 vs 4 to test the interaction? Would testing contrast 1 vs 0 be a test of the main effect of self-relevance and contrast 3 vs 0 the main effect of valence?

Thanks so much for your help!

Angela

*From: *<freesurfer-boun...@nmr.mgh.harvard.edu> on behalf of "Douglas N. Greve" <dgr...@mgh.harvard.edu>
*Reply-To: *Freesurfer support list <freesurfer@nmr.mgh.harvard.edu>
*Date: *Thursday, July 28, 2022 at 10:25 AM
*To: *"freesurfer@nmr.mgh.harvard.edu" <freesurfer@nmr.mgh.harvard.edu>
*Subject: *Re: [Freesurfer] FSFAST first level covariates

Yes, see *MailScanner has detected a possible fraud attempt from "secure-web.cisco.com" claiming to be* https://surfer.nmr.mgh.harvard.edu/fswiki/FsFastParametricModulation <https://secure-web.cisco.com/1vlnv3wLgT6AWyuomHXVnJCfD3bAT8O6KYN-6kv4DVE_Kbs9JwI6WLDqHM7UN7cfJ1TP0eQKgCtR-KXf01ehJnqsV2jW5XmAXQr0QnOlGk4--dT54zncT2aoK1njMKmN9ayqCJ_tFar2vbW-JGXSkTcg6gdUPh_mngiG7m6SxtOvACvAKVHKQXKhe7-xx2QsCh6VDDkv9vQZNEkvMseg2bTElAE9tBG4Nyws1TeLoT6NRejWCSL4Hnke9bOJGLYp7gY561tg-SfXXlzjCNawo6cgCBAIxSsMzwLR8sWZndlid_nZ0aZqf85_HgcVXWUXEoKCbQCJ_Hs2G69KcjGr8yg/https%3A%2F%2Fsurfer.nmr.mgh.harvard.edu%2Ffswiki%2FFsFastParametricModulation>

On 7/25/2022 6:56 PM, Angela Fang wrote:

    *        External Email - Use Caution *

    Hi Freesurfer community,

    I have run participants through an event-related fMRI task in
    which subjects rate whether trait adjectives are descriptive of
    themselves or not, and afterwards asked them to rate each trait
    word on emotional valence. Is it possible to include these
    individual level subjective ratings of emotional valence as
    covariates in the first level contrast in FSFAST? If so, how?

    Thanks,

    Angela

    ---

    Angela Fang, Ph.D.

    Assistant Professor
    Department of Psychology

    University of Washington

    Lab website: *MailScanner has detected a possible fraud attempt
    from "secure-web.cisco.com" claiming to be* www.uwconnectlab.com
    
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    Pronouns: she, her, hers

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