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I decided to register T1 and Flair to DIR at the beginning. with this way,
I will get the new mask in already DIR's space which means manually
segmented masks' space.

In my case, I will give two inputs to the software. The rule that applies
to every software is that the *inputs are in the same space. *I mean If you
want, you can register inputs even to atlases. That's why I think it
doesn't matter to change the reference based on the patient . Since the
register mentality is to register to high resolution, I register in
different combinations. My ınputs will not change. t1 and flair. But, If I
have a 3d Flair, I register t1 to flair. If I have a 3d t1,then I register
flair to t1.  Is there something wrong here?

Best,
Dilek

Dilek Özkan <dozkan...@gmail.com>, 30 Ağu 2022 Sal, 14:01 tarihinde şunu
yazdı:

> Hello dear all,
>
> I want to use Freesurfer-Samseg for MS lesion
> segmentation(cross-sectional).
>
> I got the T1 and Flair for this. I registered *flair to t1 *for every
> patient.
> My manual lesion masks are on DIR imaging. I am using FSL for
> registration. When I try to register my manual mask to new mask created by
> freesurfer samseg, fsl couldn't recognize the lesions.mgz extension.
>
> Or should I use t1 space for registration? i tried that one. and then, my
> registration result was really bad.
>
> As a consequence, ho should we deal with mask registration?
>
> Best,
> Dilek
>
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