External Email - Use Caution Hi,
I decided to eliminate de Female vs Male distintion leaving only three groups and the program is giving the same error. I don't know what is happening because I did the analysis without differianciating any groups and it works. So I imagine the problem comes form dividing the population into groups but i don't really understand why. Thanks, Vicente Ferrer Predoctoral Researcher BCBL http://secure-web.cisco.com/1MeTtiU5upbosDZLvO5efqUkYhjil-_OOdO3ShPfbbWnXYMtgZvjjiAvXpMSKK-qLj-4ECEVtYuCVxW4X8p8kqLB8lKYaNkttnjuFY6dLCFSzIBnIHfRMlqBtWIRbUZ92hhAIXdZxMiHLybgw3o9Ej_Uvee22_zau-EcmFlU5EDo5Lwtp_z1tSeXuPuGrDsxXM6_yFELcOhYVbug_Sk81pnd3Uy9iz8HYWxhXQw-f6Z5__Dz8tV__2u7ecI7oXpohcG0FlESJDzdJRmRA6LIQ_7tKIugv5jV5wT8MWS5VzzRKE4sHshojTZNDjDAIY83D/http%3A%2F%2Fwww.bcbl.eu Legal disclaimer/Aviso legal/Lege-oharra: http://secure-web.cisco.com/11W5WltBGFEvDsbaNKH94aEzdb5XB9OGMZWxLtvJbB4ZtRPs8tTH7HbroWOn_qo8DMm72FbvNlkOp0n0quHKKMW-35l_s0JRl6n0zNVapkZdVgV-s6bvm_wvyTVZGBOFloe7RlJ8N0QJf6DJcX2ZQOMmbzLztdOF_v13XtFMt_WDJiv2Wt4rY80kmGllz1CCy7nIosfV0fg3R_ztJ_cgcJCjrbVTzfNLRVKdLeLVG58XQ0mnPCC5aAkY79Ylnkml17jzwq9UjVN3kO4R3gna1aBHwCDglGoVeDWKPPzHcLniWbdvekzX2gssIZFmH3N0u/http%3A%2F%2Fwww.bcbl.eu%2Flegal-disclaimer ----- Original Message ----- From: "Vicente Ferrer" <v.fer...@bcbl.eu> To: "Freesurfer support list" <freesurfer@nmr.mgh.harvard.edu> Sent: Tuesday, November 29, 2022 10:16:53 AM Subject: Re: [Freesurfer] ERROR: matrix is ill-conditioned or badly scaled, condno = 1e+08 External Email - Use Caution Hi profesor Greve, I believe I have located the problem, as you will see in the code below it seems one of the groups (FemalePDMCI) has only 7 subjects and (MALEPDMCI) has 13 which means the regression won't have enough DOF. They amount of DOF needed is NregressorsDODS = Nclasses*(Nvariables+1) = 4*(4+1) = 20. Therefore I believe I would have to renounce to divide my subjects in Males and Females. Here is the output, let me know if that was the main issue. Thanks. Vicente, mri_glmfit --y $PRJDIR/FREESURFER_PPMI/stats/$image.nii.gz \ > --fsgd $PRJDIR/FREESURFER_PPMI/stats/glm_covariates_moca_groups.fsgd dods \ > --C $PRJDIR/FREESURFER_PPMI/stats/contrast_moca_groups.mtx \ > --glmdir $PRJDIR/FREESURFER_PPMI/stats/$image.corr_g_glmdir --eres-save > --illcond gdfRead(): reading /bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/glm_covariates_moca_groups.fsgd mri_glmfit-sim --glmdir $PRJDIR/FREESURFER_PPMI/stats/$image.corr_g_glmdir \ --cwp .9 \ INFO: DeMeanFlag keyword not found, DeMeaning will NOT be done. Continuous Variable Means (all subjects) 0 age 0.00273866 1.00533 1 relative_motion 0.0142075 0.995938 2 dis_duration 0.00767562 1.0031 3 moca 0.0168011 0.991508 Class Size and Means of each Continuous Variable 1 MaleHC 35 0.0125 0.2192 -0.6716 0.1872 2 MalePDCN 63 0.0523 -0.0415 0.2829 0.2509 3 MalePDMCI 13 0.4036 0.4899 0.1774 -2.0122 4 FemaleHC 20 -0.2146 -0.0406 -0.6716 0.1562 5 FemalePDCN 37 -0.1703 -0.1990 0.4623 0.4639 6 FemalePDMCI 7 0.2990 -0.1089 0.1496 -1.9348 INFO: gd2mtx_method is dods 7.3.2 cwd /export/home/vferrer cmdline mri_glmfit --y /bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/lh.atr.avg16_syn_bbr.FA_Avg.nii.gz --fsgd /bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/glm_covariates_moca_groups.fsgd dods --C /bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/contrast_moca_groups.mtx --glmdir /bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/lh.atr.avg16_syn_bbr.FA_Avg.corr_g_glmdir --eres-save --illcond sysname Linux hostname ipsnode-7-3.local machine x86_64 user vferrer FixVertexAreaFlag = 1 UseMaskWithSmoothing 1 OneSampleGroupMean 0 y /bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/lh.atr.avg16_syn_bbr.FA_Avg.nii.gz logyflag 0 usedti 0 FSGD /bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/glm_covariates_moca_groups.fsgd glmdir /bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/lh.atr.avg16_syn_bbr.FA_Avg.corr_g_glmdir IllCondOK 1 ReScaleX 1 DoFFx 0 Creating output directory /bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/lh.atr.avg16_syn_bbr.FA_Avg.corr_g_glmdir --perm 1000 1.5 abs --overwrite --perm-force --seed 1669778971 Loading y from /bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/lh.atr.avg16_syn_bbr.FA_Avg.nii.gz ... done reading. INFO: gd2mtx_method is dods Saving design matrix to /bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/lh.atr.avg16_syn_bbr.FA_Avg.corr_g_glmdir/Xg.dat Computing normalized matrix Normalized matrix condition is 1e+08 Matrix condition is 3.69944e+08 Pruning voxels by thr: 1.175494e-38 Found 47 voxels in mask Saving mask to /bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/lh.atr.avg16_syn_bbr.FA_Avg.corr_g_glmdir/mask.mgh search space = 158.625000 DOF = 145 Starting fit and test Fit completed in 0.000783333 minutes Computing spatial AR1 in volume. fMRIspatialAR1(): hit 0 voxels WARNING: no voxels in AR1 computation Residual: ar1mn = (-nan,-nan,-nan) fwhm = (-nan,-nan,-nan) -nan Writing results contrast_moca_groups maxvox sig=0.000253964 F=5.38727e-07 at index 42 0 0 seed=1670287315 Computing efficiency mri_glmfit done [vferrer@ipsnode-7-3 ~]$ [vferrer@ipsnode-7-3 ~]$ mri_glmfit-sim --glmdir $PRJDIR/FREESURFER_PPMI/stats/$image.corr_g_glmdir \ > --cwp .9 \ > --perm 1000 1.5 abs --overwrite --perm-force --seed 1669778971 cmdline mri_glmfit --y /bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/lh.atr.avg16_syn_bbr.FA_Avg.nii.gz --fsgd /bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/glm_covariates_moca_groups.fsgd dods --C /bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/contrast_moca_groups.mtx --glmdir /bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/lh.atr.avg16_syn_bbr.FA_Avg.corr_g_glmdir --eres-save --illcond mri_info --dim /bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/lh.atr.avg16_syn_bbr.FA_Avg.corr_g_glmdir/mask.mgh --o /scratch/vferrer/tmp.suxi2S Turning on 1D dim = 47 1 1 1 log file is /bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/lh.atr.avg16_syn_bbr.FA_Avg.corr_g_glmdir/perm.th15.abs.mri_glmfit-sim.log cd /export/home/vferrer /opt/freesurfer-7.3.2/bin/mri_glmfit-sim --glmdir /bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/lh.atr.avg16_syn_bbr.FA_Avg.corr_g_glmdir --cwp .9 --perm 1000 1.5 abs --overwrite --perm-force --seed 1669778971 mri_glmfit-sim 7.3.2 Tue Nov 29 16:06:54 CET 2022 Linux ipsnode-7-3.local 3.10.0-693.21.1.el7.x86_64 #1 SMP Wed Mar 7 19:03:37 UTC 2018 x86_64 x86_64 x86_64 GNU/Linux vferrer setenv SUBJECTS_DIR /bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI FREESURFER_HOME /opt/freesurfer-7.3.2 Original mri_glmfit command line: cmdline mri_glmfit --y /bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/lh.atr.avg16_syn_bbr.FA_Avg.nii.gz --fsgd /bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/glm_covariates_moca_groups.fsgd dods --C /bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/contrast_moca_groups.mtx --glmdir /bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/lh.atr.avg16_syn_bbr.FA_Avg.corr_g_glmdir --eres-save --illcond DoSim = 1 UseCache = 0 DoPoll = 0 DoPBSubmit = 0 DoBackground = 0 DiagCluster = 0 gd2mtx = dods Seed = 1669778971 fwhm = 0 nSimPerJob = 1000 1/1 Tue Nov 29 16:06:54 CET 2022 mri_glmfit --C /bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/lh.atr.avg16_syn_bbr.FA_Avg.corr_g_glmdir/tmp.mri_glmfit-sim-21231/contrast_moca_groups.mtx --sim perm 1000 1.5 /bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/lh.atr.avg16_syn_bbr.FA_Avg.corr_g_glmdir/csd/perm.th15.abs.j001 --sim-sign abs --fwhm 0 --fsgd /bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/lh.atr.avg16_syn_bbr.FA_Avg.corr_g_glmdir/y.fsgd dods --mask /bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/lh.atr.avg16_syn_bbr.FA_Avg.corr_g_glmdir/mask.mgh --y /bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/lh.atr.avg16_syn_bbr.FA_Avg.corr_g_glmdir/eres.mgh --perm-force --seed 1669778971 INFO: ignoring tag Creator INFO: ignoring tag SUBJECTS_DIR INFO: ignoring tag SynthSeed simbase /bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/lh.atr.avg16_syn_bbr.FA_Avg.corr_g_glmdir/csd/perm.th15.abs.j001 FWHM = 0.000000 gdfRead(): reading /bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/lh.atr.avg16_syn_bbr.FA_Avg.corr_g_glmdir/y.fsgd INFO: NOT demeaning continuous variables Continuous Variable Means (all subjects) 0 age 0.00273894 1.00533 1 relative_motion 0.0142074 0.995939 2 dis_duration 0.0076754 1.0031 3 moca 0.0168018 0.991509 Class Size and Means of each Continuous Variable 1 MaleHC 35 0.0125 0.2192 -0.6716 0.1872 2 MalePDCN 63 0.0523 -0.0415 0.2829 0.2509 3 MalePDMCI 13 0.4037 0.4899 0.1774 -2.0122 4 FemaleHC 20 -0.2146 -0.0406 -0.6716 0.1562 5 FemalePDCN 37 -0.1703 -0.1990 0.4623 0.4639 6 FemalePDMCI 7 0.2990 -0.1089 0.1496 -1.9348 INFO: gd2mtx_method is dods 7.3.2 cwd /export/home/vferrer cmdline mri_glmfit --C /bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/lh.atr.avg16_syn_bbr.FA_Avg.corr_g_glmdir/tmp.mri_glmfit-sim-21231/contrast_moca_groups.mtx --sim perm 1000 1.5 /bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/lh.atr.avg16_syn_bbr.FA_Avg.corr_g_glmdir/csd/perm.th15.abs.j001 --sim-sign abs --fwhm 0 --fsgd /bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/lh.atr.avg16_syn_bbr.FA_Avg.corr_g_glmdir/y.fsgd dods --mask /bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/lh.atr.avg16_syn_bbr.FA_Avg.corr_g_glmdir/mask.mgh --y /bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/lh.atr.avg16_syn_bbr.FA_Avg.corr_g_glmdir/eres.mgh --perm-force --seed 1669778971 sysname Linux hostname ipsnode-7-3.local machine x86_64 user vferrer FixVertexAreaFlag = 1 UseMaskWithSmoothing 1 OneSampleGroupMean 0 y /bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/lh.atr.avg16_syn_bbr.FA_Avg.corr_g_glmdir/eres.mgh logyflag 0 usedti 0 FSGD /bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/lh.atr.avg16_syn_bbr.FA_Avg.corr_g_glmdir/y.fsgd mask /bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/lh.atr.avg16_syn_bbr.FA_Avg.corr_g_glmdir/mask.mgh maskinv 0 glmdir (null) IllCondOK 0 ReScaleX 1 DoFFx 0 Loading y from /bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/lh.atr.avg16_syn_bbr.FA_Avg.corr_g_glmdir/eres.mgh ... done reading. INFO: gd2mtx_method is dods Computing normalized matrix Normalized matrix condition is 1e+08 Design matrix ------------------ -------------------------------- ERROR: matrix is ill-conditioned or badly scaled, condno = 1e+08 -------------------------------- -------- ERROR: READ THIS ----------------- --vvvvvvvvvvvvvvvvvvvvvvvvvvvvvv----- Possible problem with experimental design: Check for duplicate entries and/or lack of range of continuous variables within a class. If you seek help with this problem, make sure to send: 1. Your command line: mri_glmfit --C /bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/lh.atr.avg16_syn_bbr.FA_Avg.corr_g_glmdir/tmp.mri_glmfit-sim-21231/contrast_moca_groups.mtx --sim perm 1000 1.5 /bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/lh.atr.avg16_syn_bbr.FA_Avg.corr_g_glmdir/csd/perm.th15.abs.j001 --sim-sign abs --fwhm 0 --fsgd /bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/lh.atr.avg16_syn_bbr.FA_Avg.corr_g_glmdir/y.fsgd dods --mask /bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/lh.atr.avg16_syn_bbr.FA_Avg.corr_g_glmdir/mask.mgh --y /bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/lh.atr.avg16_syn_bbr.FA_Avg.corr_g_glmdir/eres.mgh --perm-force --seed 1669778971 2. The terminal output of this program (ie, everything it prints to the screen) 3. The FSGD file (/bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/lh.atr.avg16_syn_bbr.FA_Avg.corr_g_glmdir/y.fsgd) 4. The design matrix (null)/Xg.dat Attempting to diagnose further SumSq: Min=1.455099 (col 24), Max=8.657582 (col 23) ... could not determine the cause of the problem --^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^---- Vicente Ferrer Predoctoral Researcher BCBL https://secure-web.cisco.com/12Qp9WHMJD61cOgJkvr_aW6rn7hQpkT1jyv9RXJdg2TkiSGV4ecYMqVSrJsZrTFvJpZJhC0vH0uVoEDQdbgItoIEfKZg17lXpi2fJW3U8kcIMSoatAcmjpdtydeX-NaIZt6NVzDpfwOw4tBdxYcISONb_eqzXlinjivemD3iLSkr2aGkIMlKafGLbniLDjZ9BS7tg39ruLQFUCT2GTYV4aWVApSPNsmlWqoLXjOHLanskq-gdWs342P7Ild2Pp9Kglq44oS_U-1Ln7ne9MxOI7dcCWSaqYjif5x4JL7dEsvSAz78ngJetaeVHD0BAM36b/https%3A%2F%2Furldefense.com%2Fv3%2F__http%3A%2F%2Fsecure-web.cisco.com%2F1Dnpd94Rs0IQlR6VloIhAgiyFb_RpyRiiy3jpkQjDeBYo20evwIMEwITcF1H9T--PJPJsZPeYZoLed6ACMrT7GC-CubowSFeRnaVSRQSrRBGCX0QEcP4a5QZDbzB7ZMChOJTZSHSJyX8fQLdAxmGOxt4Vq9h28sx1D7ZNEO9BHFGicJaBlHgB5IYrLzKjWrkuO8Xc8uPsrap7mND0OJqEAePJ3tznONbbjjAmU70BLNm-Ag9RQNX2lEgi8VePrwkXsIPdLfaeVI33azDgT_hcRB87UzHAQ9fqqYjB_yV4umMV1YcjD_tv375GQA4fkAyZ%2Fhttp*3A*2F*2Fwww.bcbl.eu__;JSUl!!D9dNQwwGXtA!XiPiw5AqyMoLqOryJrCS9s6sz_C8XXM7uIKNGkPDTYBoZeve9zHTNzLCDXukq2Ptj7WIR8iSpzhIL5vVSQ$ Legal disclaimer/Aviso legal/Lege-oharra: https://secure-web.cisco.com/10QQqC3yL1zlnxukn9FKyjUpa-obVbh3uY9lJH7xCD98Hb2lUSRpkQc4kOil2pygA6iWHzxsyl40Z_Tod7nxgN0MjEre-j1USE8yuCdakZJ3WCQpyJJy20cNcuSdp6YwfmA5uSLr0i-kmxsXbkRdTbOngA2q_LK0iCj-ElybIemAptMIV2zsZrIJVw_Mz21B-j20bfyGpoGK0_p-L2a9HaUqY62OLp48tLL7-4DVqdHZsDRhxVlYOzx9Y9oJIo4Y3JYVAQZzjPPLV-lGiZ2hiBF7U81SAu9zzuCRrT3xJdwQ4xKTwNlUAcOFDGHHq6L3c/https%3A%2F%2Furldefense.com%2Fv3%2F__http%3A%2F%2Fsecure-web.cisco.com%2F1sTqM0Ojw4LxgB75DTbXb_pK9pbt13EhsXuwb_Y0Kfgh0j8OdYewP6cajBC54wcSjweTGKOgygwI2RXrh1RlWvsgGNeuaPWXaLdIzNs7JneyHc-MpihtlHGMbDDDG7miKoYFKIvStoRe4cQFrkP8rTdotKype-NdywiBuA4XGukqVthAp6-o7k3fvcDCSqncULKume5C7U_LPAdvhBb3rvIH3UwIOsneOZ-JWB7tlC2Lcl3TiOZ5m_EvBgtIeQXljPXtYiO_16Fg0b5kbM7A_sqTYf3SYHaQzi54cj5YHpZbpHA8KAQH_dcFYs6T4DSUD%2Fhttp*3A*2F*2Fwww.bcbl.eu*2Flegal-disclaimer__;JSUlJQ!!D9dNQwwGXtA!XiPiw5AqyMoLqOryJrCS9s6sz_C8XXM7uIKNGkPDTYBoZeve9zHTNzLCDXukq2Ptj7WIR8iSpzgKJWKVsA$ ----- Original Message ----- From: "Douglas N. Greve" <dgr...@mgh.harvard.edu> To: "freesurfer" <freesurfer@nmr.mgh.harvard.edu> Sent: Monday, November 28, 2022 3:04:50 AM Subject: Re: [Freesurfer] ERROR: matrix is ill-conditioned or badly scaled, condno = 1e+08 that is quite strange. Does it happen every time? What is the mri_glmfit-sim command line and terminal output? On 11/23/2022 2:47 PM, Vicente Ferrer wrote: > External Email - Use Caution > > Dear Freesurfer users, > > I was trying yo use mri_glmfit-sim after using mri_glmfit that run > successfully and I encounter this error: > > > ERROR: matrix is ill-conditioned or badly scaled, condno = 1e+08 > > > -------------------------------- > -------- ERROR: READ THIS ----------------- > --vvvvvvvvvvvvvvvvvvvvvvvvvvvvvv----- > Possible problem with experimental design: > Check for duplicate entries and/or lack of range of > continuous variables within a class. > If you seek help with this problem, make sure to send: > 1. Your command line: > mri_glmfit --C > /bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/lh.atr.avg16_syn_bbr.FA_Avg.corr_g_glmdir/tmp.mri_glmfit-sim-29440/contrast_moca_groups.mtx > --sim perm 1000 1.5 > /bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/lh.atr.avg16_syn_b > br.FA_Avg.corr_g_glmdir/csd/perm.th15.abs.j001 --sim-sign abs --fwhm 0 --fsgd > /bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/lh.atr.avg16_syn_bbr.FA_Avg.corr_g_glmdir/y.fsgd > dods --mask /bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/lh.atr.avg > 16_syn_bbr.FA_Avg.corr_g_glmdir/mask.mgh --y > /bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/lh.atr.avg16_syn_bbr.FA_Avg.corr_g_glmdir/eres.mgh > --perm-force --seed 1669778971 > 2. The terminal output of this program (ie, everything it prints to the > screen) > 3. The FSGD file > (/bcbl/home/public/PD_ANALYSIS/FREESURFER_PPMI/stats/lh.atr.avg16_syn_bbr.FA_Avg.corr_g_glmdir/y.fsgd) > 4. The design matrix (null)/Xg.dat > Attempting to diagnose further > SumSq: Min=1.455099 (col 24), Max=8.657582 (col 23) > ... could not determine the cause of the problem > --^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^---- > > Seems like there is a problem with the condition matrix, but I do not > understand why. Could you help me with this problem? I attached the contrast > and fsgd files > > Best, > Vicente Ferrer > Predoctoral Researcher BCBL > https://secure-web.cisco.com/1OSix7XvH4Hpvsz0Ig1bkLPL5-req1MpAIrVbcxwoogFjZ3XERv3OlbVJnbxYKhF2gxqDQm1DhAYiEauztU0eOJTRwyXqyeEW3pkuhPLb-wt-5fH0XkUOt89j7X4oGMloiMedC8hSRBV6HNFuhAsK-0gFQAe1hfgGV9qn3OJ6IG0hwM6yA0CfHJMGbnxDtpg5SVqiGDejdQnOjUy3AoRLWrWsiu_6m1yw4wz4AK0jdoVVnTZExUP3LbQ34mW9pxthxuPyvTXhr6eD9mI8q5GSw_aqLs9_lciFJw8RuFgDL99tJ9Sbz62kXVn-0XgZbpwy/https%3A%2F%2Furldefense.com%2Fv3%2F__https%3A%2F%2Fsecure-web.cisco.com%2F1LltUaRD73SETA6gdKJYUJ2TOvuENOJaNZO4-8mWNgOMdlQCoa_sUW_ZQTf95PUj8t6eYzLPTzgRh1_09ymiZA67iF7bs9VDsOjp1dPJHoJzziqEUobtfHm1Psm5QwPOXVnpmU8o6gSgXQnAbtE_6yQUfqoU_g5FGM8vtxf5Lz-WNZfUcBhWcz5-MaJpKe3yw7Hiv765avkYx6nTYAbrvcEBN7E1kMUKXM5MVlpjMB-db8O-xisYr1dJTTiikY1Ej8xYt6EDxJi-8ZvyY7Uv4K4lnSdvvZCrNXh81GdRup8H2fVad3e8VUFfPNh0VJ97Z%2Fhttps*3A*2F*2Furldefense.com*2Fv3*2F__http*3A*2F*2Fsecure-web.cisco.com*2F1kWZEOu8GTFhJvEwUHVoEpHYRwVtjwPjaW-68jFXGIsKvsccvtZ_SpRT4mbfMn9yTEj2SS5sODMuPyTAI7wxqhCmRxBRJ-35S_I8dxkyBkn-mSO5ejNKj3y_fRHlzfZYF0Y7e4avfl65oYvF1P9f6zlpO9fvp61CMx3UMDUkUt33 HANwhKrNAQrsy2Y5VCcoRrA2AKBS0Z5P-jUa88tp7dylA1Zd2jmD5f7dpneDGC1UTgcKCSiQESkTtkx8M29TK78bxICiS2DYkMxYTENKlkex0JPgoayYX8JXmUgwvPcKnzKLxI-NITvFv7ql7vHrpEha80-krYMT5O5ictU2HZA*2Fhttp*3A*2F*2Fwww.bcbl.eu__;JSUl!!D9dNQwwGXtA!TjwEwxlcphP94Eem0VV_Ac5cyRfTuBgB2oEHsWsri2po-UDTIxqY3ZvzNfn5hDA4gGsn1MkRFVGg6njUUPa9Iw$__;JSUlJSUlJSUlJSoqKg!!D9dNQwwGXtA!XiPiw5AqyMoLqOryJrCS9s6sz_C8XXM7uIKNGkPDTYBoZeve9zHTNzLCDXukq2Ptj7WIR8iSpziosOTafA$ > > Legal disclaimer/Aviso legal/Lege-oharra: > https://secure-web.cisco.com/1eewAlDYBH4yNaqR3T9LtmOW9A3ATHhSVEm7sgF9ecgPqf_a2TsCqvw-wHRjfqzH1SrPiYw5F-zy105Qq8l2tdngcU3RyRvFbGce7KidqWZMMn_4YBAQZunt9wTk_3xrnn31kLUlb-rtc_matww60ZjD_UDY1ZFB7ubDDUAEBNJYpd5M2cxQ4zLzuDqz13K7K00W6QjW7TfyetPPnSFeZbitPfEKNTv738UiZJ9qJ_k11yWy1pPuRp_6Y6KatnCPytK4VMCCcVy9T1IO_ryN_DcV9ZfHyn2WRo134rWoUxRpsFl2HaSpAhkomX11Ix-Ki/https%3A%2F%2Furldefense.com%2Fv3%2F__https%3A%2F%2Fsecure-web.cisco.com%2F1o09atTG4we7cn2fAdaM2QEicFN8DUt0dqyYKHuckWK3y6psTBwyqZwB7CeczOlHwYQlxGn7JF5Rkb48_nXkH3W10drc-q5oCO0CpsXjmsSQe9105nSRr6CUHmdt0Uhu3Fb2k8PQoDySqbnaFdbx2LfBE9Ayiugjt9iUUa94YlO3GjYp5DC_XATqa58MXUIfiKOXFosh4jPrhZsvGoDP2NV1SQEh9eX1NLLvjrvESGmpWnucHdH4BM6lAlW0kln-bLJCI3nWMMQizxmYQUa3Z2tFlDqXjblloLsrcwjyjV03t9oBT42rU5QmVVk7I73Xp%2Fhttps*3A*2F*2Furldefense.com*2Fv3*2F__http*3A*2F*2Fsecure-web.cisco.com*2F1rEQgkEB6hY4LJfH-np0OE9PS23Pj1ILuIHA5pV4sVGy6iIr-tPaz1dGNzeFeyqXXgVqPgUG9Qgp7lZdkhjdAcHDfLVn6s7EOi9wtR4KF_7pSBxwpwPdYFmAwjwozeIs_m TK37awik2WmWkYvzoV-QMyrLQrumy5vOdXlqgwK4yAk6dOtUj8cCE4shdj0ASydOPCuTVGQcNrMej809QxJJlq-1Q7gqxfnn3t8ouyZ19eLX1Q-lx0TFvoWRwwFe6tlQt7-xyz-DFdnxm9fdfvX6Oqx8jaubFX_2FfGKhpdxyfGxBbHvkSQ2U2P84Or7lYVraCUyjOe5ytoTdER0M4Zfg*2Fhttp*3A*2F*2Fwww.bcbl.eu*2Flegal-disclaimer__;JSUlJQ!!D9dNQwwGXtA!TjwEwxlcphP94Eem0VV_Ac5cyRfTuBgB2oEHsWsri2po-UDTIxqY3ZvzNfn5hDA4gGsn1MkRFVGg6ngUWVw8yQ$__;JSUlJSUlJSUlJSoqKio!!D9dNQwwGXtA!XiPiw5AqyMoLqOryJrCS9s6sz_C8XXM7uIKNGkPDTYBoZeve9zHTNzLCDXukq2Ptj7WIR8iSpzgd33v_7Q$ > > _______________________________________________ > Freesurfer mailing list > Freesurfer@nmr.mgh.harvard.edu > https://secure-web.cisco.com/1-d96koosL1MBSnuGB514qj0im3bqGCaLuYf5BFoyjnhD95zKoveysRJghVgoebLdSNVPvQf8yVIUKDnk8E4y5XW97MLzII1hqIF08sDi0Y4KkJBjzYDNE7QGMwbUZeUOF2y811h9wW7Ay5dKsnIV7A664t6-G3MPOdcwtnnO2hiKYnfk_2fQP7GvJAYYjKh_SPtgHfhx_s0g6QxR52ynK5ga2DkxD--D31UdoHi6tDA-H_e6QaQxSL6gYwCK5IhLw8P6EbCv647MbAJ93ICUeVACzgLz-7UpXGq8pHMb4i5wSSVdl-4FjVLdnPIWhKx1/https%3A%2F%2Furldefense.com%2Fv3%2F__https%3A%2F%2Fsecure-web.cisco.com%2F1QIxbHaxXLCqFkXR0jfMjY-RAyVUHfgNigYs5baNtm95tIbKN7hXuc9QKA4v0hcrD04hY5sh7avWAleZk4XOZkEZ5A2_6ee2B1tvuP2qHNL3N0crXMcp1wQrG1sEmrfAH0fQgNSIuTylOJ87CYUv83i60QqImInOhJRrOqxjSOXHQub4LqPwSBaLbSW9MFqh_sWcchCKfs-OQ1ECs_7QUQ0Gw5hijhGrkxkKQpcqImg_btaQ-S3GvxJ_KtN4w4vZuq_xAjUNFT4yxqJCb6eLTVuJdWCxBs9Kjv-cL4YVbR6BtdBwemI-VtqfTA0Y4WAqK%2Fhttps*3A*2F*2Furldefense.com*2Fv3*2F__https*3A*2F*2Fmail.nmr.mgh.harvard.edu*2Fmailman*2Flistinfo*2Ffreesurfer__;!!D9dNQwwGXtA!TjwEwxlcphP94Eem0VV_Ac5cyRfTuBgB2oEHsWsri2po-UDTIxqY3ZvzNfn5hDA4gGsn1MkRFVGg6nhZSb6T1g$__;JSUlJSUlJSUlJSU!!D9dNQwwGXtA! 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