Hi Peter, Here is an example to convert from native space to MNI305 (fsaverage) in https://surfer.nmr.mgh.harvard.edu/fswiki/mri_vol2vol
mri_vol2vol --mov orig.mgz --targ $FREESURFER_HOME/average/mni305.cor.mgz --xfm transforms/talairach.xfm --o orig-in-mni305.mgz In your case, I think you also need ‘—interp nearest’ to convert segmentation. To convert from fsaverage to native space of a subject, can you try the following? I used bert as an example. mri_vol2vol --mov bert/mri/orig.mgz --targ fsaverage/mri/aseg.mgz --xfm transforms/talairach.xfm --inv --o aseg-from-mni305.mgz --interp nearest Best, Yujing From: freesurfer-boun...@nmr.mgh.harvard.edu <freesurfer-boun...@nmr.mgh.harvard.edu> On Behalf Of P Pieperhoff Sent: Thursday, November 16, 2023 12:07 PM To: Freesurfer support list <freesurfer@nmr.mgh.harvard.edu> Subject: [Freesurfer] Transformation of volume images External Email - Use Caution Dear developers, please, may I ask you how I can transform volume images (containing discrete region labels) from the fsaverage space into the space of a given subject, and vice-versa? I tried the following command: mri_vol2vol --interp nearest --mov fsaverage/mri/aseg.mgz --o test_mask.mgz --s test001 --targ test001/mri/orig.mg<http://secure-web.cisco.com/18zhLs0yyoi6f5anIfeKiN-F1VEbpNHEjEygu8DCPePRRMe1a3jx4QEHAQ7kD_9NgtssMozXqNUTsjOs3jetomLFaKKS-TYrPODLjsmg6Jmvr-aDKJqlzzUUe-jWpXBt3EFFRhzHq-Tc1ygK4OuWuBUFXy3BgX798ZqnJB9ANvNFzdNLeovYy2s85mZfEvst-LB_nhkwwcYuCNbr1yBBmQu84PEvvUWVyYyUimGmdsWn1SuLZnAY76EMn_fL_M4OkhiBDqR30lKic7hwf72E2bNtoJVIoesBrzh8yguobZBnBN9gxTN0r-Umzvr7yFHFp/http%3A%2F%2Forig.mg> or mri_vol2vol --interp nearest --mov fsaverage/mri/aseg.mgz --o test_mask.mgz --targ test001/mri/T1.mgz --lta test001/mri/transforms/talairach.lta --m3z talairach.m3z --s test001 but there was always a large mismatch between the transformed images and the target image. Best regards, Peter
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