If you're going to go the customization route, this might be of help:

http://blog.oak-tree.us/index.php/2009/11/02/custom-lyx-nih

It talks about creating a custom layout for an existing document class.

Related posts with more examples can be found at:

http://blog.oak-tree.us/index.php/2009/11/14/customize-lyx-character-styles
(Character styles)

http://blog.oak-tree.us/index.php/2010/05/19/latex-cv-part4
(Second example of how to create a layout for an existing document
class. The other posts in the same series how to write a custom document
class.)

Best of luck in the endeavor!

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