I talked to my MD/PhD buddy this morning who was involved in setting up
the AZ trial. He was in the first tranche of those dosed, turns out he
got the placebo. He said:
Placebo here was saline.
In the earlier UK trial, they used the non- COVID virus. The
antibody test u took may not have picked up the vaccine antibodies.
I know of one local person in the trial who had a negative antibody
test and had gotten active AZ vaccine in the trial. He found out
after he was unblinded.
As far as my positive rxn to the doses but no positive antibody tests:
The vaccine and the virus can trigger different antibody profiles
and these tests are not particularly sensitive and results vary over
time from exposure
So it is then likely that I got the actual dose since the antibody test
is not to be trusted. The trial was 2/3 got the real dose (which is
encouraging), if I got a rxn, even without a positive antibody test, I
am thinking that increases the likelihood to much greater than 2/3 that
I got it. I am feeling better about resuming normal programming now.
Also, once a vax is generally available (or to me due to age group or
whatever):
When you can make an appointment for an approved vaccine, they will
unblind you at MUSC
--FT
On 1/15/21 8:03 AM, Buggered Benzmail wrote:
I went last Friday for a blood draw for the AZ trial. I was talking to the
nurse about having a reaction (Mild flu-like symptoms days 2,3 after) to both
doses and hoping that meant I got the real deal. (I cheated and got antibody
tests that were negative both times). She said the placebo in this trial was
saline, which contradicted what my friend told me that they were using an
unmodified monkey virus in the placebo too. I haven’t heard back from her on
that aspect so don’t know.
I asked about when the study would be unblinded since it was approved in U.K.
and Mexico (I think), and I was told probably in a coupla months. They also
wanted to know if I was going to have another vax available— I think they would
then unblind me to see if it was advisable to get it.
So far the rollout here has also been a CF but it has only been a short time. I
don’t hold out much hope that it will be anything but a CF here even If/when
they get their sh..stuff together. I think 70 is the age now for the first
tranche.
--FT
Sent from iPhone
On Jan 15, 2021, at 7:49 AM, Mitch Haley via Mercedes <mercedes@okiebenz.com>
wrote:
Does a swift reaction the first time imply that your body was already prepped
to deal with COVID?
Mitch.
On 2021-01-14 22:53, Karl Wittnebel via Mercedes wrote:
personally
seeing what Covid did to my sister I am happy to have received a couple of
doses even though it did give me the equivalent of the flu for a couple of
days each time.
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--
--FT
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