Ultimately, if you intend to use MyISAM, you must keep in mind that it eliminates some of your options. One problem is that MyISAM is very slow to repair after a crash. Remember, if a crash can happen, it eventually will, it's just a question of when. And MyISAM doesn't have recovery -- it only has "repair," which will not necessarily recover all of your data.
If you are not aware of Percona XtraDB Cluster, it might be interesting for you. (I work for Percona.) There is also Continuent Tungsten to consider. Frankly, though, I'd step back a bit from such microscopic focus on technologies. It looks like you need advice from someone who's done this before, to get the high-level things right before you dive deeply into details. If it's really this important, I personally wouldn't trust it to a mailing list, I'd hire someone. It's well worth it. There's Percona again, of course, but there's also MySQL, SkySQL, PalominoDB, and lots more to choose from. Baron -- MySQL General Mailing List For list archives: http://lists.mysql.com/mysql To unsubscribe: http://lists.mysql.com/mysql