Hi,

This is just a wild guess...

> I'm also pretty sure it's not a network issue. After passing
> billions of packets there isn't a single error. I'm also pretty sure
> DNS is configured properly.

Have you checked the connection between postfix and the exchange
machines? After some years, a cable can get bad, lousy, and the
packets would not pass so reliably anymore. After moving a
machine/wandering around a rack cabinet, one may have step on a cable
and disconnect it or damage it.

Bests,

Olivier

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