Colin Batchelor wrote:
Surely this is better suited to OBI-type annotations than generic OBO things?

Please describe further how "OBI-type" differs from "OBO-type". OBI is part of OBO. Do you mean quantitative information, such as detailed numerical results of experiments?

OBI-type annotations are significantly harder to pull out of text than the sorts of thing you mention on the wiki page."

Using NLP to accurately match entities from ontologies like GO is already hard enough for simple phrase recognition. Extracting descriptions of processes (e.g. 'there is a binding process with the participants 5-HT2a and Serotonin) is even harder/impossible for most currently available NLP software. If we could popularize the annotation of biomedical texts and database entries in this way, we would already have achieved a lot. I think at the moment it is preferable to start with simple annotations based on widely accepted ontologies. Once we can still aim to create more elaborate annotations when we have established a good userbase and have been accepted by the mainstream biomedical research community.

I also think that the machine-readable representation of facts about biology should have a higher priortiy than the description of experimental setups and procedures (which is the major goal of OBI and EXPO). People only have limited time and motivation to create machine-readable annotations, and it is much more useful when they spend that time on describing the RESULTS (biological facts). Of course, descriptions of experiments are also valuable, when there are sufficient resources left for creating them.

I should mention that we (RSC) are supporting http://www.aber.ac.uk/compsci/Research/bio/art/ which aims to do just that sort of thing.

Yes, I know about ART, and it looks quite promising. I am quite sure that the software and user interfaces developed by ART could also be very useful for OBO ontologies. Are there already some preliminary results, prototypical user interfaces etc.?

I am also aware of RSC's "Project Prospect", which also seems to be of interest in this context:
http://www.rsc.org/Publishing/Journals/ProjectProspect/

Cheers,
Matthias Samwald
Semantic Web Company / DERI Galway / Yale Center for Medical Informatics


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