[ccp4bb] Requested: Three-Day Data Fabrication Workshop

2012-04-02 Thread Jacob Keller
Dear CCP4BB,

due to increasing demand, it seems we should put together a workshop on
data fabrication, covering the various important topics (chaired by JHo):

--Images: the future of fabrication? How long can we rely on database
Luddism?
--Ways out: how to leave a trail of accidental data mix-ups
--Publish large or small? Cost-benefit analyses of impact factor vs. risk
of being discovered
--Pushing the envelope: how significant is two [sic] significant
--Crossing discipline boundaries: are data fabrication procedures universal?
--Build a better hofkristallrat-trap: utilization of rhetorical bombast
and indignation in reply letters

--Break-out support-session with survivors: comforting words on careers
after the fall

--Session on the inextricably-related topic of grammatical pedantry, to be
followed by a soccer (football?) match Greeks Vs. Latins

Ample funding will be available from big pharma and other industry sectors

Please submit further topics to the CCP4BB list

JPK

ps I can't believe no one mentioned the loathsome Latino-Greek multimer
in the recent curmudgeonry postings.


***
Jacob Pearson Keller
Northwestern University
Medical Scientist Training Program
email: j-kell...@northwestern.edu
***


Re: [ccp4bb] Requested: Three-Day Data Fabrication Workshop

2012-04-02 Thread David Schuller

On 04/02/12 11:15, Jacob Keller wrote:

Dear CCP4BB,

due to increasing demand, it seems we should put together a workshop 
on data fabrication, covering the various important topics (chaired by 
JHo):

...
--Break-out support-session with survivors: comforting words on 
careers after the fall




There's always economics.

--
===
All Things Serve the Beam
===
   David J. Schuller
   modern man in a post-modern world
   MacCHESS, Cornell University
   schul...@cornell.edu



Re: [ccp4bb] Requested: Three-Day Data Fabrication Workshop

2012-04-02 Thread James Kiefer
Dear Jacob,

With all due respect, you have left out a key component to successful
data fabrication in the modern age: software.  It is quite obtuse not
to have allocated at least one day of the workshop for practical
applications of Photoshop to diffraction image generation and at least
a passing coverage of whether or not Adobe Lightroom and
crystallographic presets therein will be sufficiently capable of
muddling the RCSB staff analysis of data feasibility checking.

I would very much like to see Gerard Bricogne present a keynote
lecture entitled something like, The R-Fake Parameter: A Maximum
Likelihood Modulus to Define a Minimum Acceptable Data Drift
Coefficient for Use in the Fabrication of Credibly Artificial
Diffraction Data.

I also believe that we are perhaps full of hubris as a
crystallographic community, because an entire field of faked
structural data has existed long before crystallographers even
considered manufacturing their data.  Specifically,  the molecular
modeling community has already surpassed us in their thinking on the
subject.  While we idly discuss how to properly generate false data,
they have had the foresight to abandon ALL data...and even the
starting coordinates in crystal structures - be they real or
fictitious - and publish volumes of papers entirely unencumbered by
reality or plausibility.  My hat is off to them.

Best regards,
Jim



On Mon, Apr 2, 2012 at 8:15 AM, Jacob Keller
j-kell...@fsm.northwestern.edu wrote:
 Dear CCP4BB,

 due to increasing demand, it seems we should put together a workshop on data
 fabrication, covering the various important topics (chaired by JHo):

 --Images: the future of fabrication? How long can we rely on database
 Luddism?
 --Ways out: how to leave a trail of accidental data mix-ups
 --Publish large or small? Cost-benefit analyses of impact factor vs. risk of
 being discovered
 --Pushing the envelope: how significant is two [sic] significant
 --Crossing discipline boundaries: are data fabrication procedures universal?
 --Build a better hofkristallrat-trap: utilization of rhetorical bombast
 and indignation in reply letters

 --Break-out support-session with survivors: comforting words on careers
 after the fall

 --Session on the inextricably-related topic of grammatical pedantry, to be
 followed by a soccer (football?) match Greeks Vs. Latins

 Ample funding will be available from big pharma and other industry sectors

 Please submit further topics to the CCP4BB list

 JPK

 ps I can't believe no one mentioned the loathsome Latino-Greek multimer in
 the recent curmudgeonry postings.


 ***
 Jacob Pearson Keller
 Northwestern University
 Medical Scientist Training Program
 email: j-kell...@northwestern.edu
 ***



-- 

James Kiefer, Ph.D.
Structural Biology
Genentech, Inc.
1 DNA Way,  Mailstop 27
South San Francisco, CA 94080-4990


Re: [ccp4bb] Requested: Three-Day Data Fabrication Workshop

2012-04-02 Thread Jacob Keller
Touche. I very humbly and sincerely hereby retract my previous
post--pressured by the scientific community, I felt obligated to present
something of worth to the community, and therefore completely dreamed up
the whole conference. I hope I have not inconvenienced anyone who may have
made arrangements for travel based on my previous posting.

JPK

On Mon, Apr 2, 2012 at 10:39 AM, James Kiefer kiefer.ja...@gene.com wrote:

 Dear Jacob,

 With all due respect, you have left out a key component to successful
 data fabrication in the modern age: software.  It is quite obtuse not
 to have allocated at least one day of the workshop for practical
 applications of Photoshop to diffraction image generation and at least
 a passing coverage of whether or not Adobe Lightroom and
 crystallographic presets therein will be sufficiently capable of
 muddling the RCSB staff analysis of data feasibility checking.

 I would very much like to see Gerard Bricogne present a keynote
 lecture entitled something like, The R-Fake Parameter: A Maximum
 Likelihood Modulus to Define a Minimum Acceptable Data Drift
 Coefficient for Use in the Fabrication of Credibly Artificial
 Diffraction Data.

 I also believe that we are perhaps full of hubris as a
 crystallographic community, because an entire field of faked
 structural data has existed long before crystallographers even
 considered manufacturing their data.  Specifically,  the molecular
 modeling community has already surpassed us in their thinking on the
 subject.  While we idly discuss how to properly generate false data,
 they have had the foresight to abandon ALL data...and even the
 starting coordinates in crystal structures - be they real or
 fictitious - and publish volumes of papers entirely unencumbered by
 reality or plausibility.  My hat is off to them.

 Best regards,
 Jim



 On Mon, Apr 2, 2012 at 8:15 AM, Jacob Keller
 j-kell...@fsm.northwestern.edu wrote:
  Dear CCP4BB,
 
  due to increasing demand, it seems we should put together a workshop on
 data
  fabrication, covering the various important topics (chaired by JHo):
 
  --Images: the future of fabrication? How long can we rely on database
  Luddism?
  --Ways out: how to leave a trail of accidental data mix-ups
  --Publish large or small? Cost-benefit analyses of impact factor vs.
 risk of
  being discovered
  --Pushing the envelope: how significant is two [sic] significant
  --Crossing discipline boundaries: are data fabrication procedures
 universal?
  --Build a better hofkristallrat-trap: utilization of rhetorical bombast
  and indignation in reply letters
 
  --Break-out support-session with survivors: comforting words on careers
  after the fall
 
  --Session on the inextricably-related topic of grammatical pedantry, to
 be
  followed by a soccer (football?) match Greeks Vs. Latins
 
  Ample funding will be available from big pharma and other industry
 sectors
 
  Please submit further topics to the CCP4BB list
 
  JPK
 
  ps I can't believe no one mentioned the loathsome Latino-Greek
 multimer in
  the recent curmudgeonry postings.
 
 
  ***
  Jacob Pearson Keller
  Northwestern University
  Medical Scientist Training Program
  email: j-kell...@northwestern.edu
  ***



 --

 James Kiefer, Ph.D.
 Structural Biology
 Genentech, Inc.
 1 DNA Way,  Mailstop 27
 South San Francisco, CA 94080-4990




-- 
***
Jacob Pearson Keller
Northwestern University
Medical Scientist Training Program
email: j-kell...@northwestern.edu
***


Re: [ccp4bb] Requested: Three-Day Data Fabrication Workshop

2012-04-02 Thread Gerard Bricogne
Dear James,

On Mon, Apr 02, 2012 at 08:39:41AM -0700, James Kiefer wrote:
 Dear Jacob,
 
 With all due respect, you have left out a key component to successful
 data fabrication in the modern age: software.  It is quite obtuse not
 to have allocated at least one day of the workshop for practical
 applications of Photoshop to diffraction image generation and at least
 a passing coverage of whether or not Adobe Lightroom and
 crystallographic presets therein will be sufficiently capable of
 muddling the RCSB staff analysis of data feasibility checking.
 
 I would very much like to see Gerard Bricogne present a keynote
 lecture entitled something like, The R-Fake Parameter: A Maximum
 Likelihood Modulus to Define a Minimum Acceptable Data Drift
 Coefficient for Use in the Fabrication of Credibly Artificial
 Diffraction Data.


 Wait a minute ... I have indeed been trying to understand what types of
random processes would best model errors in actual data, but that is in
order to produce better likelihood functions to refine against raw data, not
to better fake errors in fabricated data ;-) - although of course ... . 

 Your suggested title is very good! I will work on a talk, even if the
Workshop never happens.


 With best wishes,
 
  Gerard.

--
 I also believe that we are perhaps full of hubris as a
 crystallographic community, because an entire field of faked
 structural data has existed long before crystallographers even
 considered manufacturing their data.  Specifically,  the molecular
 modeling community has already surpassed us in their thinking on the
 subject.  While we idly discuss how to properly generate false data,
 they have had the foresight to abandon ALL data...and even the
 starting coordinates in crystal structures - be they real or
 fictitious - and publish volumes of papers entirely unencumbered by
 reality or plausibility.  My hat is off to them.
 
 Best regards,
 Jim
 
 
 
 On Mon, Apr 2, 2012 at 8:15 AM, Jacob Keller
 j-kell...@fsm.northwestern.edu wrote:
  Dear CCP4BB,
 
  due to increasing demand, it seems we should put together a workshop on data
  fabrication, covering the various important topics (chaired by JHo):
 
  --Images: the future of fabrication? How long can we rely on database
  Luddism?
  --Ways out: how to leave a trail of accidental data mix-ups
  --Publish large or small? Cost-benefit analyses of impact factor vs. risk of
  being discovered
  --Pushing the envelope: how significant is two [sic] significant
  --Crossing discipline boundaries: are data fabrication procedures universal?
  --Build a better hofkristallrat-trap: utilization of rhetorical bombast
  and indignation in reply letters
 
  --Break-out support-session with survivors: comforting words on careers
  after the fall
 
  --Session on the inextricably-related topic of grammatical pedantry, to be
  followed by a soccer (football?) match Greeks Vs. Latins
 
  Ample funding will be available from big pharma and other industry sectors
 
  Please submit further topics to the CCP4BB list
 
  JPK
 
  ps I can't believe no one mentioned the loathsome Latino-Greek multimer in
  the recent curmudgeonry postings.
 
 
  ***
  Jacob Pearson Keller
  Northwestern University
  Medical Scientist Training Program
  email: j-kell...@northwestern.edu
  ***
 
 
 
 -- 
 
 James Kiefer, Ph.D.
 Structural Biology
 Genentech, Inc.
 1 DNA Way,  Mailstop 27
 South San Francisco, CA 94080-4990

-- 

 ===
 * *
 * Gerard Bricogne g...@globalphasing.com  *
 * *
 * Global Phasing Ltd. *
 * Sheraton House, Castle Park Tel: +44-(0)1223-353033 *
 * Cambridge CB3 0AX, UK   Fax: +44-(0)1223-366889 *
 * *
 ===


Re: [ccp4bb] Requested: Three-Day Data Fabrication Workshop

2012-04-02 Thread Jacob Keller
Maybe we could have the workshop in Abilene?

JPK

On Mon, Apr 2, 2012 at 11:25 AM, Gerard Bricogne g...@globalphasing.comwrote:

 Dear James,

 On Mon, Apr 02, 2012 at 08:39:41AM -0700, James Kiefer wrote:
  Dear Jacob,
 
  With all due respect, you have left out a key component to successful
  data fabrication in the modern age: software.  It is quite obtuse not
  to have allocated at least one day of the workshop for practical
  applications of Photoshop to diffraction image generation and at least
  a passing coverage of whether or not Adobe Lightroom and
  crystallographic presets therein will be sufficiently capable of
  muddling the RCSB staff analysis of data feasibility checking.
 
  I would very much like to see Gerard Bricogne present a keynote
  lecture entitled something like, The R-Fake Parameter: A Maximum
  Likelihood Modulus to Define a Minimum Acceptable Data Drift
  Coefficient for Use in the Fabrication of Credibly Artificial
  Diffraction Data.


  Wait a minute ... I have indeed been trying to understand what types
 of
 random processes would best model errors in actual data, but that is in
 order to produce better likelihood functions to refine against raw data,
 not
 to better fake errors in fabricated data ;-) - although of course ... .

 Your suggested title is very good! I will work on a talk, even if the
 Workshop never happens.


 With best wishes,

  Gerard.

 --
  I also believe that we are perhaps full of hubris as a
  crystallographic community, because an entire field of faked
  structural data has existed long before crystallographers even
  considered manufacturing their data.  Specifically,  the molecular
  modeling community has already surpassed us in their thinking on the
  subject.  While we idly discuss how to properly generate false data,
  they have had the foresight to abandon ALL data...and even the
  starting coordinates in crystal structures - be they real or
  fictitious - and publish volumes of papers entirely unencumbered by
  reality or plausibility.  My hat is off to them.
 
  Best regards,
  Jim
 
 
 
  On Mon, Apr 2, 2012 at 8:15 AM, Jacob Keller
  j-kell...@fsm.northwestern.edu wrote:
   Dear CCP4BB,
  
   due to increasing demand, it seems we should put together a workshop
 on data
   fabrication, covering the various important topics (chaired by JHo):
  
   --Images: the future of fabrication? How long can we rely on database
   Luddism?
   --Ways out: how to leave a trail of accidental data mix-ups
   --Publish large or small? Cost-benefit analyses of impact factor vs.
 risk of
   being discovered
   --Pushing the envelope: how significant is two [sic] significant
   --Crossing discipline boundaries: are data fabrication procedures
 universal?
   --Build a better hofkristallrat-trap: utilization of rhetorical
 bombast
   and indignation in reply letters
  
   --Break-out support-session with survivors: comforting words on careers
   after the fall
  
   --Session on the inextricably-related topic of grammatical pedantry,
 to be
   followed by a soccer (football?) match Greeks Vs. Latins
  
   Ample funding will be available from big pharma and other industry
 sectors
  
   Please submit further topics to the CCP4BB list
  
   JPK
  
   ps I can't believe no one mentioned the loathsome Latino-Greek
 multimer in
   the recent curmudgeonry postings.
  
  
   ***
   Jacob Pearson Keller
   Northwestern University
   Medical Scientist Training Program
   email: j-kell...@northwestern.edu
   ***
 
 
 
  --
 
  James Kiefer, Ph.D.
  Structural Biology
  Genentech, Inc.
  1 DNA Way,  Mailstop 27
  South San Francisco, CA 94080-4990

 --

 ===
 * *
 * Gerard Bricogne g...@globalphasing.com  *
 * *
 * Global Phasing Ltd. *
 * Sheraton House, Castle Park Tel: +44-(0)1223-353033 *
 * Cambridge CB3 0AX, UK   Fax: +44-(0)1223-366889 *
 * *
 ===




-- 
***
Jacob Pearson Keller
Northwestern University
Medical Scientist Training Program
email: j-kell...@northwestern.edu
***


Re: [ccp4bb] Requested: Three-Day Data Fabrication Workshop

2012-04-02 Thread Pavel Afonine
Yep,

phenix.fake_f_obs

is available for use since April 22, 2011, but I made it such that it will
only do the right thing in experienced hands -;) and I wouldn't teach it
unless you sign a disclaimer -:)

It's good for developers though who want to do fully controllable numeric
experiments to test ideas.

Pavel

On Mon, Apr 2, 2012 at 8:39 AM, James Kiefer kiefer.ja...@gene.com wrote:

 Dear Jacob,

 With all due respect, you have left out a key component to successful
 data fabrication in the modern age: software.  It is quite obtuse not
 to have allocated at least one day of the workshop for practical
 applications of Photoshop to diffraction image generation and at least
 a passing coverage of whether or not Adobe Lightroom and
 crystallographic presets therein will be sufficiently capable of
 muddling the RCSB staff analysis of data feasibility checking.

 I would very much like to see Gerard Bricogne present a keynote
 lecture entitled something like, The R-Fake Parameter: A Maximum
 Likelihood Modulus to Define a Minimum Acceptable Data Drift
 Coefficient for Use in the Fabrication of Credibly Artificial
 Diffraction Data.

 I also believe that we are perhaps full of hubris as a
 crystallographic community, because an entire field of faked
 structural data has existed long before crystallographers even
 considered manufacturing their data.  Specifically,  the molecular
 modeling community has already surpassed us in their thinking on the
 subject.  While we idly discuss how to properly generate false data,
 they have had the foresight to abandon ALL data...and even the
 starting coordinates in crystal structures - be they real or
 fictitious - and publish volumes of papers entirely unencumbered by
 reality or plausibility.  My hat is off to them.

 Best regards,
 Jim



 On Mon, Apr 2, 2012 at 8:15 AM, Jacob Keller
 j-kell...@fsm.northwestern.edu wrote:
  Dear CCP4BB,
 
  due to increasing demand, it seems we should put together a workshop on
 data
  fabrication, covering the various important topics (chaired by JHo):
 
  --Images: the future of fabrication? How long can we rely on database
  Luddism?
  --Ways out: how to leave a trail of accidental data mix-ups
  --Publish large or small? Cost-benefit analyses of impact factor vs.
 risk of
  being discovered
  --Pushing the envelope: how significant is two [sic] significant
  --Crossing discipline boundaries: are data fabrication procedures
 universal?
  --Build a better hofkristallrat-trap: utilization of rhetorical bombast
  and indignation in reply letters
 
  --Break-out support-session with survivors: comforting words on careers
  after the fall
 
  --Session on the inextricably-related topic of grammatical pedantry, to
 be
  followed by a soccer (football?) match Greeks Vs. Latins
 
  Ample funding will be available from big pharma and other industry
 sectors
 
  Please submit further topics to the CCP4BB list
 
  JPK
 
  ps I can't believe no one mentioned the loathsome Latino-Greek
 multimer in
  the recent curmudgeonry postings.
 
 
  ***
  Jacob Pearson Keller
  Northwestern University
  Medical Scientist Training Program
  email: j-kell...@northwestern.edu
  ***



 --

 James Kiefer, Ph.D.
 Structural Biology
 Genentech, Inc.
 1 DNA Way,  Mailstop 27
 South San Francisco, CA 94080-4990



Re: [ccp4bb] Requested: Three-Day Data Fabrication Workshop

2012-04-02 Thread aaleshin
Dear James,
With all due respect, you have left out a key component to successful data 
fabrication in the modern age: THE MOLECULAR REPLACEMENT.
Since almost all new structures have more or less close homologues in PDB, a 
smart fabricator should use their experimental data as a template. It will be 
more difficult to detect than the data built from the calculated structural 
factors.

To prevent future fabrication attempts, we do not need submitting  detector 
images, partially processed structural data such as unmerged  structural 
factors would work, and they do not take that much space. The switch to the 
new format  could be done in no time

Alex


On Apr 2, 2012, at 8:39 AM, James Kiefer wrote:

 Dear Jacob,
 
 With all due respect, you have left out a key component to successful
 data fabrication in the modern age: software.  It is quite obtuse not
 to have allocated at least one day of the workshop for practical
 applications of Photoshop to diffraction image generation and at least
 a passing coverage of whether or not Adobe Lightroom and
 crystallographic presets therein will be sufficiently capable of
 muddling the RCSB staff analysis of data feasibility checking.
 
 I would very much like to see Gerard Bricogne present a keynote
 lecture entitled something like, The R-Fake Parameter: A Maximum
 Likelihood Modulus to Define a Minimum Acceptable Data Drift
 Coefficient for Use in the Fabrication of Credibly Artificial
 Diffraction Data.
 
 I also believe that we are perhaps full of hubris as a
 crystallographic community, because an entire field of faked
 structural data has existed long before crystallographers even
 considered manufacturing their data.  Specifically,  the molecular
 modeling community has already surpassed us in their thinking on the
 subject.  While we idly discuss how to properly generate false data,
 they have had the foresight to abandon ALL data...and even the
 starting coordinates in crystal structures - be they real or
 fictitious - and publish volumes of papers entirely unencumbered by
 reality or plausibility.  My hat is off to them.
 
 Best regards,
 Jim
 
 
 
 On Mon, Apr 2, 2012 at 8:15 AM, Jacob Keller
 j-kell...@fsm.northwestern.edu wrote:
 Dear CCP4BB,
 
 due to increasing demand, it seems we should put together a workshop on data
 fabrication, covering the various important topics (chaired by JHo):
 
 --Images: the future of fabrication? How long can we rely on database
 Luddism?
 --Ways out: how to leave a trail of accidental data mix-ups
 --Publish large or small? Cost-benefit analyses of impact factor vs. risk of
 being discovered
 --Pushing the envelope: how significant is two [sic] significant
 --Crossing discipline boundaries: are data fabrication procedures universal?
 --Build a better hofkristallrat-trap: utilization of rhetorical bombast
 and indignation in reply letters
 
 --Break-out support-session with survivors: comforting words on careers
 after the fall
 
 --Session on the inextricably-related topic of grammatical pedantry, to be
 followed by a soccer (football?) match Greeks Vs. Latins
 
 Ample funding will be available from big pharma and other industry sectors
 
 Please submit further topics to the CCP4BB list
 
 JPK
 
 ps I can't believe no one mentioned the loathsome Latino-Greek multimer in
 the recent curmudgeonry postings.
 
 
 ***
 Jacob Pearson Keller
 Northwestern University
 Medical Scientist Training Program
 email: j-kell...@northwestern.edu
 ***
 
 
 
 -- 
 
 James Kiefer, Ph.D.
 Structural Biology
 Genentech, Inc.
 1 DNA Way,  Mailstop 27
 South San Francisco, CA 94080-4990


Re: [ccp4bb] Requested: Three-Day Data Fabrication Workshop

2012-04-02 Thread Lynn F. Ten Eyck
Given some of the etymological discussion, and the suggestion of economics as 
an alternative career, it would seem that the workshop should be held in either 
Italy or Greece.

Lynn Ten Eyck

On Apr 2, 2012, at 9:30 AM, Jacob Keller wrote:

 Maybe we could have the workshop in Abilene?
 
 JPK
 
 On Mon, Apr 2, 2012 at 11:25 AM, Gerard Bricogne g...@globalphasing.com 
 wrote:
 Dear James,
 
 On Mon, Apr 02, 2012 at 08:39:41AM -0700, James Kiefer wrote:
  Dear Jacob,
 
  With all due respect, you have left out a key component to successful
  data fabrication in the modern age: software.  It is quite obtuse not
  to have allocated at least one day of the workshop for practical
  applications of Photoshop to diffraction image generation and at least
  a passing coverage of whether or not Adobe Lightroom and
  crystallographic presets therein will be sufficiently capable of
  muddling the RCSB staff analysis of data feasibility checking.
 
  I would very much like to see Gerard Bricogne present a keynote
  lecture entitled something like, The R-Fake Parameter: A Maximum
  Likelihood Modulus to Define a Minimum Acceptable Data Drift
  Coefficient for Use in the Fabrication of Credibly Artificial
  Diffraction Data.
 
 
 Wait a minute ... I have indeed been trying to understand what types of
 random processes would best model errors in actual data, but that is in
 order to produce better likelihood functions to refine against raw data, not
 to better fake errors in fabricated data ;-) - although of course ... .
 
 Your suggested title is very good! I will work on a talk, even if the
 Workshop never happens.
 
 
 With best wishes,
 
  Gerard.
 
 --
  I also believe that we are perhaps full of hubris as a
  crystallographic community, because an entire field of faked
  structural data has existed long before crystallographers even
  considered manufacturing their data.  Specifically,  the molecular
  modeling community has already surpassed us in their thinking on the
  subject.  While we idly discuss how to properly generate false data,
  they have had the foresight to abandon ALL data...and even the
  starting coordinates in crystal structures - be they real or
  fictitious - and publish volumes of papers entirely unencumbered by
  reality or plausibility.  My hat is off to them.
 
  Best regards,
  Jim
 
 
 
  On Mon, Apr 2, 2012 at 8:15 AM, Jacob Keller
  j-kell...@fsm.northwestern.edu wrote:
   Dear CCP4BB,
  
   due to increasing demand, it seems we should put together a workshop on 
   data
   fabrication, covering the various important topics (chaired by JHo):
  
   --Images: the future of fabrication? How long can we rely on database
   Luddism?
   --Ways out: how to leave a trail of accidental data mix-ups
   --Publish large or small? Cost-benefit analyses of impact factor vs. risk 
   of
   being discovered
   --Pushing the envelope: how significant is two [sic] significant
   --Crossing discipline boundaries: are data fabrication procedures 
   universal?
   --Build a better hofkristallrat-trap: utilization of rhetorical bombast
   and indignation in reply letters
  
   --Break-out support-session with survivors: comforting words on careers
   after the fall
  
   --Session on the inextricably-related topic of grammatical pedantry, to be
   followed by a soccer (football?) match Greeks Vs. Latins
  
   Ample funding will be available from big pharma and other industry sectors
  
   Please submit further topics to the CCP4BB list
  
   JPK
  
   ps I can't believe no one mentioned the loathsome Latino-Greek multimer 
   in
   the recent curmudgeonry postings.
  
  
   ***
   Jacob Pearson Keller
   Northwestern University
   Medical Scientist Training Program
   email: j-kell...@northwestern.edu
   ***
 
 
 
  --
 
  James Kiefer, Ph.D.
  Structural Biology
  Genentech, Inc.
  1 DNA Way,  Mailstop 27
  South San Francisco, CA 94080-4990
 
 --
 
 ===
 * *
 * Gerard Bricogne g...@globalphasing.com  *
 * *
 * Global Phasing Ltd. *
 * Sheraton House, Castle Park Tel: +44-(0)1223-353033 *
 * Cambridge CB3 0AX, UK   Fax: +44-(0)1223-366889 *
 * *
 ===
 
 
 
 -- 
 ***
 Jacob Pearson Keller
 Northwestern University
 Medical Scientist Training Program
 email: j-kell...@northwestern.edu
 ***



Re: [ccp4bb] Requested: Three-Day Data Fabrication Workshop

2012-04-02 Thread Bernhard Rupp (Hofkristallrat a.D.)
I wish to point out (because I remembered just now) that I offered a similar
service after the Murthy scandal on this BB in August 2007:

 

http://www.ruppweb.org/new_comp/frame_maker.html

 

-  and JK proposed a value-added contribution.

 

See attached. Btw, Kim Henrick's analysis from 2007 still seems rather lucid
to me.

 

Best, BR

 

From: CCP4 bulletin board [mailto:CCP4BB@JISCMAIL.AC.UK] On Behalf Of Jacob
Keller
Sent: Monday, April 02, 2012 8:15 AM
To: CCP4BB@JISCMAIL.AC.UK
Subject: [ccp4bb] Requested: Three-Day Data Fabrication Workshop

 

Dear CCP4BB,

 

due to increasing demand, it seems we should put together a workshop on data
fabrication, covering the various important topics (chaired by JHo):

 

--Images: the future of fabrication? How long can we rely on database
Luddism?

--Ways out: how to leave a trail of accidental data mix-ups

--Publish large or small? Cost-benefit analyses of impact factor vs. risk of
being discovered

--Pushing the envelope: how significant is two [sic] significant

--Crossing discipline boundaries: are data fabrication procedures universal?

--Build a better hofkristallrat-trap: utilization of rhetorical bombast
and indignation in reply letters

 

--Break-out support-session with survivors: comforting words on careers
after the fall

 

--Session on the inextricably-related topic of grammatical pedantry, to be
followed by a soccer (football?) match Greeks Vs. Latins

 

Ample funding will be available from big pharma and other industry sectors

 

Please submit further topics to the CCP4BB list

 

JPK

 

ps I can't believe no one mentioned the loathsome Latino-Greek multimer in
the recent curmudgeonry postings.

 

 

***
Jacob Pearson Keller
Northwestern University
Medical Scientist Training Program
email: j-kell...@northwestern.edu
***

---BeginMessage---
In response to your website, I was thinking of a startup collecting old
photos of crystals (harder
to computer-generate) to go with the frames--interested in a collaboration?
Maybe you could just
put a link on your page?

JPK

==Original message text===
On Fri, 17 Aug 2007 3:24:45 pm CDT Bernhard Rupp wrote:

The PDB is missing a business opportunity. If authors pay
1000s of dollars for publication in high impact journals,
they might as well pay a few bucks for image deposition.
If I could get my images stored reliably and perpetually 
for something like $20-50 a pop, I'd do it. Do you know
where your favourite frames from 1998 are? 

Image storage is a good idea *in itself*, but as an enforcement tool
it only will make the *exceedingly few* Reids more inventive.

PS: Frames for sale. 
http://www.ruppweb.org/new_comp/frame_maker.html
-Original Message-
From: CCP4 bulletin board [mailto:CCP4BB@JISCMAIL.AC.UK] On Behalf Of Kim
Henrick
Sent: Friday, August 17, 2007 7:04 AM
To: CCP4BB@JISCMAIL.AC.UK
Subject: [ccp4bb] Richard Reid and the PDB

After Richard Reid more than 100 million people each year have to have their
shoes examined and one effect is that older buildings like Heathrow Terminal
3 is the most painful place on earth, the cost of someone trying light their
shoelaces has affect us all.


The discussion on archiving image data sets -  I guess that less than 1% of
the image sets for PDB entries
   are useful to software development (and can be got privately)  I guess
that maybe 1 in 10,000 entries have a series problem that
   may require referees to look at the images (and can be
   accessed upon demand)


The cost of disks for your PC - kitchen table disks from a supermarket, may
be $1 per Gbyte on USB i/o but an archive centre required to maintain the
data will probably need RAID 0/1 - RAID 10, this has high performance, and
highest data protection, i.e. can tolerate multiple drive failures, but has
high redundancy cost overhead, if you havent noticed a large collection of
disks has failures. Look up the problems that the series of Landsat
satellites have had from 1980 onwards with the problems arising out of the
volume of data and the short life of computer compatible tapes and optical
discs. Archiving data lacks glamour it’s the boring day to day rectification
and storage of information, very little money gets spent on this task,for
remote sensing the most significant cost is transmission/correction and
archiving the data - Three semi-trailer loads of Landsat tapes were found
(literally) moldering in a damp basement in Baltimore after people and
funding agencies lost interest. Oh yes and detectors change every 5 years
and processing software gets lost.

At the EBI before we even get a single disk we pay ,000 for a cabinet
- disks cost around  for 300gigbytes (and not the best disks these are
around the same cost for 146 Gigbytes). Disk technology changes every 5
years - an archive cost is to recover the data ever 5 years onto the next
generation of hardware. Molecular