Re: [Freesurfer] Hippocampal subfields and aseg

2012-07-24 Thread Koen Van Leemput
Hi Michael, I can answer the subfield part - perhaps someone else (Bruce?) can chime in regarding aseg. For the subfields, there isn't really a standard routine to go in and alter the segmentation results. You could try to alter the aseg hippocampus segmentation as this is what is used to

[Freesurfer] Paired t-test with independent samples

2012-07-24 Thread Jürgen Hänggi
Dear statistic experts We have done statistics between two independent groups using an independent t-test. One group consistent of 13 male patients and the other group consistent of 13 male control subjects who were matched to the patients with respect to age and education (in years). The

[Freesurfer] (no subject)

2012-07-24 Thread Vincenzo Pierro
Please, could anyone let me know how to perform statistical analysis in QDEC to look at the interaction between two genes on cortical thickness?    Vincenzo Pierro ___ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu

[Freesurfer] Interaction between two genes on cortical thickness

2012-07-24 Thread Vincenzo Pierro
Please, could anyone let me know how to perform statistical analysis in QDEC to look at the interaction between two genes on cortical thickness?      Vincenzo Pierro___ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu

Re: [Freesurfer] Hippocampal subfields and aseg

2012-07-24 Thread Bruce Fischl
Hi Michael we have seen that occasionally, but that looks like a pretty bad example. If you upload the subject I'll take a look. We have some unreleased tools that can help with this (a relatively small manual intervention). cheers Bruce On Mon, 23 Jul 2012, Murray, Michael wrote:

Re: [Freesurfer] questions about SurfArea and meancurv

2012-07-24 Thread Yang, Daniel
Dear all, After studying the freesurferstats2table script for a while, I think I figure out what these surfaces are. Below is my understanding. Please correct me if I am mistaken! In the aparc_area_lh.txt, the surface area should be one based on the pial surface, not the white surface,

Re: [Freesurfer] questions about SurfArea and meancurv

2012-07-24 Thread Bruce Fischl
Hi Daniel sorry, I meant to respond to your previous post. We generate statistics for both the white and pial surfaces. For historical reasons the ones without specific surface name in them represent the white surface (i.e. the pial ones will all say pial). We can produce both Gaussian and

Re: [Freesurfer] questions about SurfArea and meancurv

2012-07-24 Thread Yang, Daniel
Hi Bruce, Thanks for the correction! So according to your email, the correct interpretation should be, In the aparc_area_lh.txt, the surface area is one based on the white surface, not the pial surface, based on the historical naming. In the aparc_meancurv_lh.txt, the mean curvature is one

Re: [Freesurfer] questions about SurfArea and meancurv

2012-07-24 Thread Bruce Fischl
yes, that's right Bruce On Tue, 24 Jul 2012, Yang, Daniel wrote: Hi Bruce, Thanks for the correction! So according to your email, the correct interpretation should be, In the aparc_area_lh.txt, the surface area is one based on the white surface, not the pial surface, based on the

Re: [Freesurfer] Paired t-test with independent samples

2012-07-24 Thread Douglas N Greve
Hi Jurgen, I don't think it is too unusual to do this kind of thing, ie, a paired test where pairing is based on gender, age, and education, but you know your data and field better than I do. It is not the case that one is more conservative than another (they are the same) assuming that the

Re: [Freesurfer] Measuring total cortical volume

2012-07-24 Thread Douglas N Greve
Those are the values I mentioned before (lhCortex, etc, see below). I don't understand your concern about the deep structures. doug ps please remember to post to the freesurfer list and not to me directly. thanks! On 07/24/2012 06:56 AM, Emelie Andersson wrote: Thank You for your answer. I

Re: [Freesurfer] (no subject)

2012-07-24 Thread Douglas N Greve
Set up each gene as a discrete factor, then look for a difference. doug On 07/24/2012 08:56 AM, Vincenzo Pierro wrote: Please, could anyone let me know how to perform statistical analysis in QDEC to look at the interaction between two genes on cortical thickness? Vincenzo Pierro

Re: [Freesurfer] Paired t-test with independent samples

2012-07-24 Thread Yizhou Ma
Hi Jurgen, I actually just came across a similar situation in which I tried to convince my PI that a paired t test is more appropriate. In my humble opinion, if you are applying an independent group test, than the matching design is irrelevant in this analysis because you're not taking any

[Freesurfer] tracula RAM memory ?...

2012-07-24 Thread Gonzalo Rojas Costa
Hi: How much memory needs tracula to process a DTI study ?... Because my PC (Ubuntu Linux, 4GB RAM) exit because it can't allocate memory in trac-preproc... There exist any tip trick in such a case?... Sincerely, -- Gonzalo Rojas Costa Laboratory for Advanced Medical Image Processing

Re: [Freesurfer] How to register FLAIR to T1?

2012-07-24 Thread Douglas N Greve
Hi Ed, the problem appears to be with the initialization. For some reason, fslregister is not initializing this data well. I don't know why the call directly to flirt works (and I've verified here that it does). When I initialize by hand or with SPM, bbregister works fine with the standard

Re: [Freesurfer] Freesurfer Question

2012-07-24 Thread Alexandra Tanner
Hi Doug, Yes, sorry about that! I realized after I'd sent the email to you that I should've sent the email to the freesurfer list as well. We were hoping to look at volume in subcortical regions of the brain -- basal ganglia, hippocampus, amygdala, etc. Do know if there are commands to do the

Re: [Freesurfer] Freesurfer Question

2012-07-24 Thread Douglas N Greve
Hi Alex, do you want to do it on an ROI basis? If so, you can use asegstats2table to create a table of your subjects at the two time points, then import this table into SPSS. Or you can run the table through mri_glmfit to do the paired-t analysis. doug On 07/24/2012 01:56 PM, Alexandra Tanner

Re: [Freesurfer] tracula RAM memory ?...

2012-07-24 Thread Anastasia Yendiki
Hi Gonzalo - You'll find some recent emails on this in the archives. In short, you can try deleting a few lines from the file: $FREESURFER_HOME/trctrain/trainlist.txt For every line you're deleting, you're removing a subject from the tract atlas that tracula uses. There are currently 33

Re: [Freesurfer] Paired t-test with independent samples

2012-07-24 Thread jorge luis
A paired t-test is a special case of a repeated measures ANOVA with a single within-subject factor and two levels. You should use it when the measurements in one group are correlated with the measurements in the other group and there is a within-subject effect that persists across paired

Re: [Freesurfer] Freesurfer Question

2012-07-24 Thread Alexandra Tanner
Hi Doug, We don't want to do ROIs because we're trying to get a thickness map of the entire subcortical region of the brain. Prior to trying this, we ran a within subjects paired analysis that gave us thickness maps of cortical surface. We ran these commands to look at the thickness maps in each

Re: [Freesurfer] Freesurfer Question

2012-07-24 Thread Douglas N Greve
Hi Alex, what do you mean by a thickness map of the subcortical region? The subcortical structure are usually characterized by simple volume measurements (eg, hippocampus has a volume of XXX mm3). There are tools out there to do voxel based morphometry. Is this what you mean? doug On