Re: [Freesurfer] Multiple comparison using Monte Carlo

2019-12-05 Thread Ting Li
External Email - Use Caution Dear Dr. Douglas, Thank you so much! Best regards, Ting On Thu, Dec 5, 2019 at 11:45 AM Greve, Douglas N.,Ph.D. < dgr...@mgh.harvard.edu> wrote: > I've attached a couple of papers > > On 12/3/19 9:24 PM, Ting Li wrote: > > > > External

Re: [Freesurfer] Multiple comparison using Monte Carlo

2019-12-03 Thread Ting Li
External Email - Use Caution Dear Dr. Douglas, Thank you so much. I have difficulty to understand z map is essentially an infinite # of subjects. Before smooth, there is no GLM analysis. Does the smooth include in the GLM process? Best regards, Ting On Tue, Dec 3, 2019 at 2:14

Re: [Freesurfer] Multiple comparison using Monte Carlo

2019-12-03 Thread Greve, Douglas N.,Ph.D.
On 12/3/2019 1:36 PM, Ting Li wrote: External Email - Use Caution Dear Dr. Douglas, Thank you so much for all the answers. I have two more questions. 1, When the Monte Carlo simulation is doing, how does one simulation is done? * synthesize z map (synthesize z map for how many

Re: [Freesurfer] Multiple comparison using Monte Carlo

2019-12-03 Thread Ting Li
External Email - Use Caution Dear Dr. Douglas, Thank you so much for all the answers. I have two more questions. 1, When the Monte Carlo simulation is doing, how does one simulation is done? - synthesize z map (synthesize z map for how many subjects?) - smooth z map (You

Re: [Freesurfer] Multiple comparison using Monte Carlo

2019-12-02 Thread Ting Li
External Email - Use Caution Dear Dr. Douglas, Thank you so much for your explanation. You really helped me a lot! Best regards, Ting On Mon, Dec 2, 2019 at 1:59 PM Greve, Douglas N.,Ph.D. < dgr...@mgh.harvard.edu> wrote: > Correct. This is no different than, eg, a t-test.

Re: [Freesurfer] Multiple comparison using Monte Carlo

2019-12-02 Thread Greve, Douglas N.,Ph.D.
Correct. This is no different than, eg, a t-test. Look in the back of a stats book from the 1950s and you will find a table of t-ratios and corresponding p-values. Obviously, they did not have access to any of the data being analyzed today:), but the tables are still valid. On 12/2/2019 2:03

Re: [Freesurfer] Multiple comparison using Monte Carlo

2019-12-02 Thread Ting Li
External Email - Use Caution Dear Dr. Douglas, Thank you so much for your detailed response. The simulation here is to get the probability of a maximum cluster that size or larger in the cached CSD files. It checks the probability of the cluster size but have nothing to do with

Re: [Freesurfer] Multiple comparison using Monte Carlo

2019-12-02 Thread Greve, Douglas N.,Ph.D.
On 12/2/2019 11:58 AM, Ting Li wrote: External Email - Use Caution Dear Dr. Douglas, Thank you so much for your quick response! You saved my half life. From the introduction of clusterwise correction for multiple comparisons, I have a few questions. 1, What is the null hypothesis

Re: [Freesurfer] Multiple comparison using Monte Carlo

2019-12-02 Thread Ting Li
External Email - Use Caution Dear Dr. Douglas, Thank you so much for your quick response! You saved my half life. From the introduction of clusterwise correction for multiple comparisons, I have a few questions. 1, What is the null hypothesis here ? 2, What is a z map? Do you

Re: [Freesurfer] Multiple comparison using Monte Carlo

2019-12-02 Thread Greve, Douglas N.,Ph.D.
That will use the pre-computed ("cached") CSD files distributed with FreeSurfer. This used 10,000 iterations. On 12/1/2019 11:34 PM, Ting Li wrote: External Email - Use Caution Dear Freesurfer Expert: I have used the simulation code as show below: mri_glmfit-sim \ --glmdir

[Freesurfer] Multiple comparison using Monte Carlo

2019-12-01 Thread Ting Li
External Email - Use Caution Dear Freesurfer Expert: I have used the simulation code as show below: mri_glmfit-sim \ --glmdir lh.gender_age.glmdir \ --cache 4 neg \ --cwp 0.05\ --2spaces My question is how many iterations are done during this simulation? I didn’t