email:
-
From: Pavel belonon...@optonline.net
Date: Thu, 16 Jan 2014 13:05:54 -0500 (EST)
To:lgibian...@quantpharm.com,nmusers@globomaxnm.com
Subject: RE: [NMusers] backward integration from t-a to t
Hello Leonid,
Thank you bein helpful. You got the main point. AUC
05:54 -0500 (EST)
To: lgibian...@quantpharm.com, nmusers@globomaxnm.com
Subject: RE: [NMusers] backward integration from t-a to t
Hello Leonid,
Thank you bein helpful. You got the main point. AUC is a better
predictor than concentration, but it has to disppear very slowly but
surely.
A pote
om <mailto:nmusers@globomaxnm.com>
Subject: RE: [NMusers] backward integration from t-a to t
Hello Leonid,
Thank you bein helpful. You got the main point. AUC is a better
predictor than concentration, but it has to disppear very slowly but
surely.
A potential challenge is biological meaning of th
...@quantpharm.com, nmusers@globomaxnm.com
Subject: RE: [NMusers] backward integration from t-a to t
Hello Leonid,
Thank you bein helpful. You got the main point. AUC is a better
predictor than concentration, but it has to disppear very slowly but
surely.
A potential challenge is biological meaning of this
: [NMusers] backward integration from t-a to t
Hello Leonid,
Thank you bein helpful. You got the main point. AUC is a better
predictor than concentration, but it has to disppear very slowly but
surely.
A potential challenge is biological meaning of this approach. It will
be necessary to
Leonid
Original email:
-
From: Pavel Belo non...@optonline.net
Date: Tue, 14 Jan 2014 13:45:18 -0500 (EST)
To: robert.ba...@iconplc.com, nmusers@globomaxnm.com
Subject: [NMusers] backward integration from t-a to t
Dear Robert,
Â
Efficacy is frequently considered a function of AUC. (A
To: Bauer, Robert
Cc: nmusers@globomaxnm.com
Subject: [NMusers] backward integration from t-a to t
Dear Robert,
Efficacy is frequently considered a function of AUC. (AUC is just an
integral. It is obvious how to calculate AUC any software which can
solve ODE.) A disadvanta
t;http://www.iconplc.com/>
From: owner-nmus...@globomaxnm.com [mailto:owner-nmus...@globomaxnm.com] On
Behalf Of Pavel Belo
Sent: Tuesday, January 14, 2014 1:45 PM
To: Bauer, Robert
Cc: nmusers@globomaxnm.com
Subject: [NMusers] backward integration from t-a to t
Dear Robert,
Efficacy is freq
c: nmusers@globomaxnm.com
Subject: [NMusers] backward integration from t-a to t
Dear Robert,
Efficacy is frequently considered a function of AUC. (AUC is just an
integral. It is obvious how to calculate AUC any software which can
solve ODE.) A disadvantage of this model of e
Please never mind. Someone suggested tose tlag, which is a simple
and efficient enough way to do it.
Regards,
Pavel
Dear Robert,
Efficacy is frequently considered a function of AUC. (AUC is just an
integral. It is obvious how to calculate AUC any software whic
[mailto:owner-nmus...@globomaxnm.com] On
Behalf Of Pavel Belo
Sent: 14 January 2014 18:45
To: Bauer, Robert
Cc: nmusers@globomaxnm.com
Subject: [NMusers] backward integration from t-a to t
Dear Robert,
Efficacy is frequently considered a function of AUC. (AUC is just an integral.
It is obvious
AUC=C*TAU. So roughly, A2 can
be
interpreted as AUC over the interval of 1/K0.
Leonid
Original email:
-
From: Pavel Belo non...@optonline.net
Date: Tue, 14 Jan 2014 13:45:18 -0500 (EST)
To: robert.ba...@iconplc.com, nmusers@globomaxnm.com
Subject: [NMusers] backward integration
Dear Robert,
Efficacy is frequently considered a function of AUC. (AUC is just an
integral. It is obvious how to calculate AUC any software which can
solve ODE.) A disadvantage of this model of efficacy is that the effect
is irreversable because AUC of concentration can only increa
13 matches
Mail list logo
