Something's amiss upstream - without any search results there's nothing to
work with.

-----Original Message-----
From: [email protected]
[mailto:[email protected]] On Behalf Of Amanda
Sent: Tuesday, December 16, 2008 8:37 AM
To: spctools-discuss
Subject: [spctools-discuss] Re: Reposting- I haven't gotten a response back
yet to my PeptideProphetParser.exe error


No, I did not see that.  My pep.xml looks like this:

<?xml version="1.0" encoding="UTF-8"?>
<?xml-stylesheet type="text/xsl" href="http://regis-
web.systemsbiology.net/pepXML_std.xsl"?>
<msms_pipeline_analysis date="2008-12-09T10:13:08" xmlns="http://regis-
web.systemsbiology.net/pepXML" xmlns:xsi="http://www.w3.org/2001/
XMLSchema-instance" xsi:schemaLocation="http://regis-
web.systemsbiology.net/pepXML c:\Inetpub\wwwrootpepXML_v110.xsd"
summary_xml="c:/Inetpub/wwwroot/ISB/data/18337.RAW_analysis_test/
18337.pep.xml">
<msms_run_summary base_name="c:/Inetpub/wwwroot/ISB/data/
18337.RAW_analysis_test/18337" msManufacturer="Thermo Scientific"
msModel="LTQ FT" msIonization="NSI" msMassAnalyzer="FTMS"
msDetector="unknown" raw_data_type="raw" raw_data=".mzXML">
<sample_enzyme name="trypsin">
<specificity cut="KR" no_cut="P" sense="C"/>
</sample_enzyme>
<search_summary base_name="c:/Inetpub/wwwroot/ISB/data/
18337.RAW_analysis_test/18337" search_engine="SEQUEST"
precursor_mass_type="average" fragment_mass_type="average"
out_data_type="out" out_data=".tgz" search_id="1">
<search_database local_path="C:\Inetpub\wwwroot\ISB\data
\Pmarinus_NC_005072.fasta" type="AA"/>
<aminoacid_modification aminoacid="C" massdiff="58.0055"
mass="161.1443" variable="Y" symbol="*"/>
<aminoacid_modification aminoacid="M" massdiff="15.9949"
mass="147.1875" variable="Y" symbol="#"/>
<aminoacid_modification aminoacid="K" massdiff="43.0058"
mass="171.1799" variable="Y" symbol="@"/>
<parameter name="peptide_mass_tol" value="2.000"/>
<parameter name="fragment_ion_tol" value="0.250"/>
<parameter name="ion_series" value=" 0 1 1 0.0 1.0 0.0 0.0 0.0 0.0 0.0
1.0 0.0"/>
<parameter name="max_num_differential_AA_per_mod" value="4"/>
<parameter name="nucleotide_reading_frame" value="0"/>
<parameter name="num_output_lines" value="10"/>
<parameter name="remove_precursor_peak" value="0"/>
<parameter name="ion_cutoff_percentage" value="0.0"/>
<parameter name="match_peak_count" value="0"/>
<parameter name="match_peak_allowed_error" value="1"/>
<parameter name="match_peak_tolerance" value="1.0"/>
<parameter name="protein_mass_filter" value="0 0"/>
<parameter name="sequence_header_filter" value=""/>
</search_summary>
</msms_run_summary>
</msms_pipeline_analysis>


On Dec 16, 11:12 am, "Brian Pratt" <[email protected]> wrote:
> A "tag" in XML is something like <Hi_I_am_a_tag>
>
> So what you're looking for is text beginning "<spectrum_query".
>
>
>
> -----Original Message-----
> From: [email protected]
>
> [mailto:[email protected]] On Behalf Of Amanda
> Sent: Tuesday, December 16, 2008 7:42 AM
> To: spctools-discuss
> Subject: [spctools-discuss] Re: Reposting- I haven't gotten a response
back
> yet to my PeptideProphetParser.exe error
>
> Can you explain what a spectrum query tag is?
>
> On Dec 15, 10:51 pm, "David Shteynberg"
> <[email protected]> wrote:
> > Hi Amanda,
>
> > The error message says:
>
> > running: "C:/Inetpub/tpp-bin/InteractParser "interact.pep.xml" "c:/
> > Inetpub/wwwroot/ISB/data/18337.RAW_analysis_test/18337.pep.xml""
> >  file 1: c:/Inetpub/wwwroot/ISB/data/18337.RAW_analysis_test/
> > 18337.pep.xml
> >  processed altogether 0 results
>
> > This means there was a problem reading data from your pepXML file.
> > Can you verify that your pepXML fie has spetrum_query tags?
>
> > Thanks,
> > -David
>
> > On Mon, Dec 15, 2008 at 2:59 PM, Natalie Tasman
>
> > <[email protected]> wrote:
> > > Hello Amanda,
>
> > > Please try the latest release, 4.1.1 (November) instead of 4.0.2
(July),
> as
> > > many bugs have been fixed.  Perhaps this issue has already been
> addressed.
>
> > > Best wishes,
> > > Natalie
>
> > > On Mon, Dec 15, 2008 at 2:51 PM, Amanda <[email protected]>
wrote:
>
> > >> I'm trying to run Protein prophet but keep running into the same
> > >> error.
> > >> So far, I started with a .RAW file (290MB) and converted it to both
> > >> mzXML (667Mb) and mzML (1GB). I then did a Database search and got
> > >> the
> > >> expected folder with .dta files (2852 files, 1-15KB each).  I
> > >> converted these to a .pep.xml file (3KB).  The problem comes when I
> > >> try to analyze with Peptide Prophet and Protein Prophet. I get the
> > >> following files: interact.pep.xml,
> > >> interact.pep.shtml,interact.pep.xsl, and interact.pep.xml.tmp.axxxxx.
> > >> I then get the following error messages:
> > >> --------------------------------------
> > >> Popup message:
> > >> PeptideProphetParser.exe has encountered a problem and needs to
> > >> close.  We are sorry for the inconvenience.
> > >> --------------------------------------
> > >> Error Signature:
> > >> szAppName : PeptideProphetParser.exe     szAppVer : 0.0.0.0
> > >> szModName : PeptideProphetParser.exe     szModVer : 0.0.0.0
> > >> offset : 00019ec0
> > >> --------------------------------------
> > >> Error Report Contents:
> > >> C:\DOCUME~1\AMANDA~1\LOCALS~1\Temp
> > >> \WERb712.dir00\PeptideProphetParser.exe.mdmp
> > >> C:\DOCUME~1\AMANDA~1\LOCALS~1\Temp\WERb712.dir00\appcompat.txt
> > >> --------------------------------------
> > >> Log File/ Output Files:
>
> > >>    * c:/Inetpub/wwwroot/ISB/data/18337.RAW_analysis_test/
> > >> interact.pep.shtml [ View ]
> > >>    * c:/Inetpub/wwwroot/ISB/data/18337.RAW_analysis_test/
> > >> interact.prot.shtml (file not found: not created or deleted?)
>
> > >>  Command 1 [Tue Dec 9 09:33:43 2008]               [ Show / Hide ]
>
> > >>  run_in c:/Inetpub/wwwroot/ISB/data/18337.RAW_analysis_test;
> > >> xinteract  -Ninteract.pep.xml -p0.05 -x20 -Op c:/Inetpub/wwwroot/ISB/
> > >> data/18337.RAW_analysis_test/18337.pep.xml
>
> > >> xinteract (TPP v4.0 JETSTREAM rev 2, Build 200807011544 (MinGW))
>
> > >> running: "C:/Inetpub/tpp-bin/InteractParser "interact.pep.xml" "c:/
> > >> Inetpub/wwwroot/ISB/data/18337.RAW_analysis_test/18337.pep.xml""
> > >>  file 1: c:/Inetpub/wwwroot/ISB/data/18337.RAW_analysis_test/
> > >> 18337.pep.xml
> > >>  processed altogether 0 results
>
> > >>  results written to file c:/Inetpub/wwwroot/ISB/data/
> > >> 18337.RAW_analysis_test/interact.pep.xml
>
> > >>  direct your browser to
> > >>http://localhost/ISB/data/18337.RAW_analysis_test/interact.pep.shtml
>
> > >> command completed in 1 sec
>
> > >> running: "C:/Inetpub/tpp-bin/PeptideProphetParser "interact.pep.xml"
> > >> MINPROB=0.05 EXTRAITRS=20"
> > >>  (SEQUEST)
> > >> MS Instrument info: Manufacturer: UNKNOWN, Model: UNKNOWN,
> > >> Ionization:
> > >> UNKNOWN, Analyzer: UNKNOWN, Detector: UNKNOWN
>
> > >> command "C:/Inetpub/tpp-bin/PeptideProphetParser "interact.pep.xml"
> > >> MINPROB=0.05 EXTRAITRS=20" failed: Unknown error
>
> > >> command "C:/Inetpub/tpp-bin/PeptideProphetParser "interact.pep.xml"
> > >> MINPROB=0.05 EXTRAITRS=20" exited with non-zero exit code:
> > >> -1073741819
> > >> QUIT - the job is incomplete
>
> > >> Command FAILED- Hide quoted text -
>
> > - Show quoted text -- Hide quoted text -
>
> - Show quoted text -


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