Thank you David. You are right, I attach in this new link the 3 files you
need: mzML, fasta and pep.xml.

Link: PEAKS Dataset
<https://drive.google.com/drive/folders/1Q3LF1wRTM62KfS20dfXmToQMY9ji9Dug>

I hope you can do something. Thanks anyway for your concern.

Best regards,
Sergio

--------------------------
Sergio Ciordia Higuera
Proteomics Facility
National Center for Biotechnology
C\Darwin, 3
Universidad Autónoma de Madrid
Cantoblanco
28049 Madrid (Spain)
Phone: +34 91 585 4540 / 4695
Fax: +34 91 585 4506


El jue, 10 oct 2024 a las 1:34, David Shteynberg (<
[email protected]>) escribió:

> Thank you Sergio!  Would you mind also sending the mzML data and the
> sequence database that goes along with these search results from PEAKS?
>
> Best,
> -David
>
> On Oct 9, 2024, at 3:58 PM, Sergio Ciordia <[email protected]> wrote:
>
> Hi David,
>
> Thank you for your quick and honest response. I am sorry to hear that you
> have no funds to continue TPP implementation. I hope this problem will be
> solved.
> Nevertheless, I appreciate your consideration of evaluating a sample file.
> This file contains what the PEAKS team calls ‘Peptide output in pepxml’. I
> hope it is adequate but in any case I don't think there will be a problem
> in getting a suitable data output for TPP if necessary. The other format
> that can be obtained is mzidentML in case it is of interest.
>
> LINK: pepXML PEAKS sample
> <https://drive.google.com/file/d/185t5m7vJPLQAj8vVpcviX_p58DHZfyAB/view?usp=sharing>
>
> Thanks again for your reply.
>
> Best regards,
> Sergio
>
> --------------------------
> Sergio Ciordia Higuera
> Proteomics Facility
> National Center for Biotechnology
> C\Darwin, 3
> Universidad Autónoma de Madrid
> Cantoblanco
> 28049 Madrid (Spain)
> Phone: +34 91 585 4540 / 4695
> Fax: +34 91 585 4506
>
>
> El jue, 10 oct 2024 a las 0:46, David Shteynberg (<
> [email protected]>) escribió:
>
>> Hello Sergio,
>>
>> Thank you for your email.  As you know PEAKS is not a search engine that
>> we have integrated in the TPP, mainly because we have not had any requests
>> for this feature before your email.  It is something that can be done with
>> a bit of work and testing, but unfortunately there is currently no funding
>> for us to continue this work.  I wish I had a more satisfying answer to
>> give you, but perhaps, if you can forward your sample pep.xml file, we can
>> do this if more funding becomes available.
>>
>> Best,
>> -David
>>
>> On Oct 9, 2024, at 3:35 PM, Sergio Ciordia <[email protected]> wrote:
>>
>> Hi,
>>
>> I have been using TPP for some time now mainly to validate with
>> PeptideProphet the results I get with various search engines and to
>> generate a spectral library that I use in various programs. The thing is
>> that in my lab we are now using PEAKS (v12) and the output is really good.
>> I was wondering if it would be possible to include in TPP an analysis
>> pipeline of the PEAKS data from the pep.xml file generated by the program.
>> I know it is a commercial software but the output is very good and I
>> would be very grateful if you could consider including it like Sequest or
>> Mascot. I think it would not be complicated since they already have the
>> pep.xml output, it would only have to be compatible with XInteract to be
>> able to validate peptide-spectrum matches.
>>
>> If necessary I can provide a sample pep.xml file.
>>
>> Thank you very much.
>>
>> Best regards,
>> Sergio
>>
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