check bash profile, and or systemmd that change how and where temp files are stored, is dovecot started via systemmd ?

export | grep tmp
[root@myhostname ~]# export | grep tmp
declare -x PWD="/tmp"

what is the homedir of user running this ?
/home/username/....
possible you have set spamd / spamc scan limit bigger then what it have room for in fs quotas ?, i cant see here if you have it enabled
no, it scans only up to 500KB email...it seems the default on CentOS 7

as i see it something is forceing all tmp files to be in /tmp including what really just should be maildir tmp dir

if you use dovecot move the question over there, since its not a spamassassin issue, any chance of you run something in chroot ?
sorry, I don't understand why you think of dovecot...can you explain? anyway yes, dovecot is started by systemd

thanks

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