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MMR Vaccine and Autism
(Measles, Mumps, and Rubella) 

FACT SHEET 

 

Key Messages

·         MMR vaccine protects children against dangerous, even deadly, diseases.

·         Because signs of autism may appear at around the same time children receive 
the MMR vaccine, some parents may worry that the vaccine causes autism.

·         Carefully performed scientific studies have found no relationship between 
MMR vaccine and autism.

·         The CDC continues to recommend two doses of MMR vaccine for all children.

Facts

·         MMR is a combination vaccine that protects children from measles, mumps, and 
rubella (also known as German measles). The first dose of the vaccine is usually given 
to children 12 to 15 months old. The second dose is usually given between 4 and 6 
years of age.

·         In 1998, a study of autistic children raised the question of a connection 
between MMR vaccine and autism.

·         The 1998 study has a number of limitations. For example, the study was very 
small, involving only 12 children. This is too few cases to make any generalizations 
about the causes of autism. In addition, the researchers suggested that MMR 
vaccination caused bowel problems in the children, which then led to autism. However, 
in some of the children studied, symptoms of autism appeared before symptoms of bowel 
disease.

·         Other larger studies have found no relationship between MMR vaccine and 
autism. For example, researchers in the UK studied the records of 498 children with 
autism born between 1979 and 1998. They found:

Ø      the percentage of children with autism who received MMR vaccine was the same as 
the percentage of unaffected children in the region who received MMR vaccine

Ø      there was no difference in the age of diagnosis of autism in vaccinated and 
unvaccinated children 

Ø      the onset of "regressive" symptoms of autism did not occur within 2, 4, or 6 
months of receiving the MMR vaccine.

·         Groups of experts, including the American Academy of Pediatrics, agree that 
MMR vaccine is not responsible for recent increases in the number of children with 
autism.

·         There is no published scientific evidence showing that there is any benefit 
to separating the combination MMR vaccine into three individual shots.

For more information

   For information on Autism Spectrum Disorders - 
http://www.cdc.gov/ncbddd/dd/ddautism.htm  
      
   For in-depth information on the MMR and autism theory 
http://www.cdc.gov/nip/vacsafe/concerns/autism/autism-mmr.htm  
    
   National Immunization Hotline: 
English (800) 232-2522
Spanish (800) 232-0233  

 
 


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