Research/Senior Associate - Structural Biology - Metabasis Therapeutics Inc. - San Diego, CA
We invite you to join the team of committed and talented scientists to develop novel drug towards metabolic and related diseases. You will have an excellent opportunity to apply the science of protein crystallography to expedite the discovery and development of drugs to treat and cure conditions such as diabetes and obesity. We are seeking a motivated and enthusiastic candidate to join the Structural Biology group. The primary function of the Research/Senior Research Associate will be crystallization and optimization of proteins crystals including membrane proteins with and without small molecule ligands, in preparation for data collection. Hands-on experience forming protein target: inhibitor complexes by cocrystallization or soaking protocols. Demonstrated mastery of crystal soaking, freezing, and the preparation of samples for synchrotron data collection. Experience with protein purification, protein chemistry, analysis of purity and homogeneity. This position actively interacts with a broad team of medicinal chemists, computational chemists, and biologists. The successful candidate will possess a Masters degree, or a Bachelors degree with at least three to five years of relevant industrial/academic research experience in a high throughput structural biology environment as applied to structure based drug discovery. The ideal candidate will also have experience in protein crystallization utilizing both manual and automated systems. Capability of working on multiple projects simultaneously and organize his/her workload so as to meet deadlines. Strong communication and interpersonal skills are a must. You will have an excellent opportunity to learn and grow by participating, presenting and interacting with scientists across multiple disciplines in the areas of drug discovery. For consideration, please submit your resume and a cover letter with names and contact information of three references to: Metabasis Therapeutics, Inc. Human Resources Dept. 11119 North Torrey Pines Road La Jolla, CA 92037 Phone: (858) 587-2770 Fax: (858) 458-3504 email: [EMAIL PROTECTED] All inquiries will be treated confidentially.
