just to add a factoid, from the ADNI data set, 793 subjects processed by
freesurfer:
Volume Mean: StdDev:
------------------- ----- -------
Left-Hippocampus 3184.335 604.930
Right-Hippocampus 3233.753 621.896
seems pretty symmetric, with the right being slightly larger (but within
std). this subject set is a mix of controls, MCI and AD patients.
n.
On Fri, 2009-08-14 at 17:53 -0400, Bruce Fischl wrote:
> is your segmentation protocol the same as the one we base our automated
> segmentation on? For example, are fimbria and alveus considered part of
> the hippocampus?
>
> As far as left/right switches go, do you have any fiducial markers (e.g.
> vitamin E tablets) in the images?
>
> cheers
> Bruce
> On Sat, 15 Aug 2009, caoaize wrote:
>
> >
> > Hi, there,
> >
> >
> > I have some problem for the hippocampus segmentation results.
> >
> > 1. My structural data are originally in par-rec file. I used r2agui to
> > convert them into .nii format, then use recon-all -i to convert the .nii
> > data into freesurfer .mgz format. Based on these operations, I run
> > recon-all -all on all my data, the statistical report show that the mean
> > left hippocampus volume is bigger than the right one, while literature
> > shows that the right one should be bigger. This problem continuously
> > appeared in our different studies. I am not sure whether it is r2agui's
> > problem, which changed the oritation of the structural data. Do you have
> > any idea?
> >
> > 2. After autosegmentation, we did a statistical comparison analysis
> > between automatic segmentation and manual segmentation, and the
> > correlation is quite low, less than 80%, which is not acceptable for us.
> >
> > 3. Can I edit the auto segmentation results in Freesurfer if we think the
> > auto segmentation is not good enough in some area?
> >
> > I will be really appreciated for your help.
> >
> > Aize
> >
> >
> > _________________________________________________________________
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