Dear FreeSurfur Gurus,
It appears that the using -use-mritotal worked to get past the talairach
error.

 Thank you for all your help. We really appreciate it.

Joshua




On Wed, Nov 2, 2011 at 7:01 PM, Bruce Fischl <fis...@nmr.mgh.harvard.edu>wrote:

> Hi Michael
>
> we found that the conversion to unsigned character sometimes compressed
> the brain into only a couple of bits of the dynamic range. We know use the
> talairach xform to locate the center of the brain and make sure that a ball
> centered at the tal origin occupies a lot of the histogram. This helped in
> a number of cases, but maybe the makes the tal xform more sensitive to bias
> fields and strange intensity scalings.
>
> Bruce
>
> On Wed, 2 Nov 2011, Michael Waskom wrote:
>
>  Hi,
>> What was the reason for this switch?  Intuitively it seems that a
>> bias-corrected image is likely to get a better registration (since I
>> assume the target has essentially uniform intensities).
>>
>> Michael
>>
>> On Wed, Nov 2, 2011 at 1:15 PM, Nick Schmansky <ni...@nmr.mgh.harvard.edu>
>> wrote:
>>      no, v5.0 uses nu.mgz as input to the talairach_avi routine, whereas
>> v5.1
>>      uses orig.mgz.
>>
>>      its hard to say why it would fail for some subjects but not others,
>>      other than head positioning and to some degree ventricle size makes a
>>      difference.
>>
>>      n.
>>
>> On Wed, 2011-11-02 at 16:10 -0400, Joshua Lee wrote:
>> > Thanks Nick,
>> >
>> > Is use-mritotal equivalent to what version 5.0 does by default?
>> >
>> > Also,  any suggestions on why this talairach error would occur only on
>> > a portion of my data, despite all being collected with the same
>> > imaging protocol, same conversions from dicom, etc?
>> > -
>> >
>> > Joshua Lee
>> >
>> > Graduate Student
>> > Center for Mind and Brain &
>> >
>> > Department of Psychology
>> >
>> > University of California, Davis
>> > 530.747.3805
>> >
>> >
>> > On Wed, Nov 2, 2011 at 4:02 PM, Nick Schmansky
>> > <ni...@nmr.mgh.harvard.edu> wrote:
>> >         joshua,
>> >
>> >         try adding -use-mritotal to the end of your recon-all
>> >         command.  it will
>> >         use an alternate way to compute the talairach.xfm which works
>> >         better on
>> >         some data.
>> >
>> >         the change from v5.0 to v5.1 in the talairach stage was that
>> >         in v5.1,
>> >         the talairach.xfm is needed to compute nu.mgz, so the
>> >         talairach stage
>> >         needs to precede the nu_correct stage.  this means the
>> >         talairach stage
>> >         can no longer use nu.mgz as input, which seems to work better
>> >         than
>> >         orig.mgz for some data (and is the case for your data).
>> >
>> >         in the next release of freesurfer, recon-all will
>> >         automatically try the
>> >         alternate method (mritotal) if the default talairach_avi
>> >         method fails
>> >         the tal-check.
>> >
>> >         n.
>> >
>> >
>> >
>> >         On Wed, 2011-11-02 at 08:45 -0400, Bruce Fischl wrote:
>> >         > can you send us an example that works in 5.0 and fails in
>> >         5.1?
>> >         >
>> >         > thanks
>> >         > Bruce
>> >         > On Wed, 2 Nov
>> >         > 2011, Joshua Lee wrote:
>> >         >
>> >         > > Small Update: Error Disappears if Using Freesurfer version
>> >         5.0 instead of
>> >         > > 5.1. However, since I am keenly interested in the
>> >         hippocampal-subfield
>> >         > > segmentation capabilities of the most recent version, I am
>> >         loathe to regress
>> >         > > to an earlier version of FreeSurfer
>> >         > > -
>> >         > > Joshua Lee
>> >         > > Graduate Student
>> >         > > Center for Mind and Brain &
>> >         > > Department of Psychology
>> >         > > University of California, Davis
>> >         > > 530.747.3805
>> >         > >
>> >         > >
>> >         > > On Wed, Nov 2, 2011 at 2:29 AM, Joshua Lee
>> >         <jki...@ucdavis.edu> wrote:
>> >         > >       #@# Talairach Failure Detection Wed Nov  2 02:03:32
>> >         EDT 2011
>> >         > >       /home/virtualuser/freesurfer/**subjects/test005/mri
>> >         > >
>> >         > >        talairach_afd -T 0.005 -xfm
>> >         transforms/talairach.xfm
>> >         > >
>> >         > >       I am receiving the error (pasted below) on about
>> >         half of my
>> >         > >       scans, despite all cans using same protocol. I
>> >         detect no obvious
>> >         > >       issue with the quality of the images. I have
>> >         original dicoms,
>> >         > >       and am using mri_convert to save into a single .mgz
>> >         (or .nii,
>> >         > >       doesn't neem to make a difference), and the
>> >         unpredictability of
>> >         > >       the error makes diagnosis problematic. TKMedit2
>> >         reveals
>> >         > >       absolutely wacky registrations. I am processing on
>> >         Freesurfer
>> >         > >       5.1, and have replicated issue on two different
>> >         installations. I
>> >         > >       am designing a new longitudinal study inheriting the
>> >         same
>> >         > >       imaging protocol and I do not want to get in a
>> >         situation
>> >         > >       demanding manual editing of the talairach. Can
>> >         anyone help me
>> >         > >       out? Thanks, Joshua
>> >         > >
>> >         > >       ERROR: talairach_afd: Talairach Transform:
>> >         > >       transforms/talairach.xfm ***FAILED*** (p=0.0030,
>> >         pval=0.0000 <
>> >         > >       threshold=0.0050)
>> >         > >       Manual Talairach alignment may be necessary, or
>> >         > >       include the -notal-check flag to skip this test,
>> >         > >       making sure the -notal-check flag follows -all
>> >         > >       or -autorecon1 in the command string.
>> >         > >       See
>> >         > >
>> >         http://surfer.nmr.mgh.harvard.**edu/fswiki/FsTutorial/**
>> Talairach <http://surfer.nmr.mgh.harvard.edu/fswiki/FsTutorial/Talairach>
>> >         > >       Linux FreeSurfer 2.6.28-11-generic #42-Ubuntu SMP
>> >         Fri Apr 17
>> >         > >       01:57:59 UTC 2009 i686 GNU/Linux
>> >         > >
>> >         > >       recon-all -s test005 exited with ERRORS at Wed Nov
>> >          2 02:03:32
>> >         > >       EDT 2011
>> >         > >
>> >         > >       For more details, see the log file
>> >         > >
>> >           /home/virtualuser/freesurfer/**subjects/test005/scripts/**
>> recon-all.log
>> >         > >       To report a problem, see
>> >         > >
>> >         
>> > http://surfer.nmr.mgh.harvard.**edu/fswiki/BugReporting<http://surfer.nmr.mgh.harvard.edu/fswiki/BugReporting>
>> >         > >
>> >         > >       -
>> >         > > Joshua Lee
>> >         > > Graduate Student
>> >         > > Center for Mind and Brain &
>> >         > > Department of Psychology
>> >         > > University of California, Davis
>> >         > > 530.747.3805
>> >         > >
>> >         > >
>> >         > >
>> >         > >
>> >
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