I tried using corratio and it seems to have fixed the registration issue.
I'm very new to this so just want to make sure I did it correctly before I
move forward. Should the command line look something like this if I am
running it in this individuals dmri directory:


flirt -in dwi_orig.nii.gz -ref brain_anat.nii.gz -out
lowb_brain_anat.flt.nii.gz -omat diff2anat.flt.mat -cost corratio


Thanks so much for your help.

Kiely

On Wed, May 16, 2012 at 10:12 AM, Priti Srinivasan <
rspr...@nmr.mgh.harvard.edu> wrote:

> you have to run flirt commandline separately to check if it solves your
> problem.
>
>
> > Is this something I can change in my dmrirc file or do I need to run
> flirt
> > on it's own?
> >
> > Thanks,
> >
> > Kiely
> >
> > On Wed, May 16, 2012 at 9:27 AM, Priti Srinivasan <
> > rspr...@nmr.mgh.harvard.edu> wrote:
> >
> >> Kiely, For flirt, try using corratio, cost function instead of
> >> mutualinfo
> >> (which is the default in trac-all) to see if that solves your
> >> registration
> >> problem.
> >>
> >>
> >> > Hi Kiely - Looks like you used flirt for the intra-subject
> >> registration,
> >> > so you can look in trac-all.log for the flirt command line that
> >> registers
> >> > diffusion to anatomical and play around with the parameters.
> >> >
> >> > You can also use bbregister instead of flirt for the intra-subject
> >> > registration - it has the option to initialize with flirt or with SPM.
> >> >
> >> > Hope this helps,
> >> > a.y
> >> >
> >> > On Wed, 16 May 2012, Kiely Donnelly wrote:
> >> >
> >> >> Hi Priti - Thanks for your help. The inter-subject registration seems
> >> to
> >> >> have run OK, but there must be something wrong with the intra-subject
> >> >> registration. When I try to view it using freeview, it's completely
> >> dark
> >> >> - I
> >> >> don't see a brain at all. Is there a way to troubleshoot this?
> >> >> Thanks,
> >> >>
> >> >> Kiely
> >> >>
> >> >> On Wed, May 9, 2012 at 2:08 PM, Priti Srinivasan
> >> >> <rspr...@nmr.mgh.harvard.edu> wrote:
> >> >>       Hi Kiely,
> >> >>
> >> >>       Have you checked your inter and intra subject registrations?
> >> The
> >> >>       control
> >> >>       points going off the dwi is not only for one paths but for all
> >> >>       the paths.
> >> >>       If the registration goes terribly wrong, this can happen. You
> >> >>       can take a
> >> >>       look at
> >> >>
> >> >>       /dmri/lowb_brain_anat.flt.nii.gz (For intra subject
> >> registration
> >> >>       diff-anat)
> >> >>
> >> >>       and
> >> >>
> >> >>       /dmri/brain_anat_mni.nii.gz (For inter-subject registration
> >> >>       anat-mni)
> >> >>
> >> >>       I would start by checking that first.
> >> >>
> >> >>       Priti
> >> >>
> >> >>       > Hello--
> >> >>       >
> >> >>       > I have run Tracula successfully for ~75 healthy subjects.
> >> >>       However, the
> >> >>       > pathway reconstruction seems to fail for a handful of people.
> >> >>       I've
> >> >>       > attached
> >> >>       > the log file for one of these subjects. It appears that the
> >> >>       control points
> >> >>       > are not within the dwi. A similar problem occurred in a
> >> >>       subject with
> >> >>       > substantial signal loss in the dwi, but that doesn't seem to
> >> >>       be the case
> >> >>       > for this particular person. I have been creating the entire
> >> >>       set of tracts,
> >> >>       > but at this point, I'm only interested in the SLFt and SLFp.
> >> >>       >
> >> >>       > Thanks,
> >> >>       >
> >> >>       > Kiely
> >> >> > _______________________________________________
> >> >> > Freesurfer mailing list
> >> >> > Freesurfer@nmr.mgh.harvard.edu
> >> >> > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
> >> >>
> >> >>
> >> >>
> >> >> The information in this e-mail is intended only for the person to
> >> whom
> >> >> it is
> >> >> addressed. If you believe this e-mail was sent to you in error and
> >> the
> >> >> e-mail
> >> >> contains patient information, please contact the Partners Compliance
> >> >> HelpLine at
> >> >> http://www.partners.org/complianceline . If the e-mail was sent to
> >> you
> >> >> in error
> >> >> but does not contain patient information, please contact the sender
> >> >> and properly
> >> >> dispose of the e-mail.
> >> >>
> >> >>
> >> >>
> >> >>
> >> >> --
> >> >> Kiely M. Donnelly, M.A.
> >> >> Doctoral Candidate, Clinical Neuropsychology
> >> >> University of Cincinnati
> >> >>
> >> >>_______________________________________________
> >> > Freesurfer mailing list
> >> > Freesurfer@nmr.mgh.harvard.edu
> >> > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
> >>
> >>
> >
> >
> > --
> > Kiely M. Donnelly, M.A.
> > Doctoral Candidate, Clinical Neuropsychology
> > University of Cincinnati
> >
>
>


-- 
Kiely M. Donnelly, M.A.
Doctoral Candidate, Clinical Neuropsychology
University of Cincinnati
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