Hi Bruce,

Will do.  Thanks again.

-Clark

On Sep 3, 2012, at 2:33 PM, Bruce Fischl wrote:

> Hi Clark
> 
> sorry, the end of the summer has been a period when things slip through the 
> cracks. I think what you want is possible without a talairach or aseg, but it 
> will need to wait for Doug to get back. Can you repost at the end of next 
> week?
> Bruce
> 
> 
> On Thu, 30 Aug 2012, Clark Fisher wrote:
> 
>> Thanks Michael, I'll look into Nipy's FDR tools.  I actually started this
>> thread asking for help getting mri_surfcluster running for my situation (I
>> have no talraich .xfm and no segmentation for my monkeys).  The silence on
>> that topic suggest that it might not be possible, or it's at least not known
>> to possible.
>> Thanks again everyone.
>> -Clark
>> On Aug 29, 2012, at 6:55 PM, Michael Waskom wrote:
>> 
>>      Hi Clark,
>> If you're loading the data into Python anyway to use with PySurfer,
>> Nipy seems to have some utilities to do an FDR correction
>> (docs/source). I've never used these, but they look pretty
>> straightforward.
>> Also it looks like FDR is built into mri_surfcluster.
>> Best,
>> Michael
>> On Wed, Aug 29, 2012 at 2:08 PM, Clark Fisher
>> <cfis...@mail.rockefeller.edu> wrote:
>>      Hi Sebastian,
>> 
>>      I think you are right, both about tksurfer thresholding
>>      and the correct interpretation of FDR. As you point out
>>      though, there is some value in having maps that show how
>>      relatively well different points on the surface fit your
>>      model.
>> 
>>      At the very least, is there any way to automate the
>>      retrieving of the threshold that tksurfer provides? I'd
>>      still also be interested in some adjustment to the whole
>>      map, if there's a way to do that as well.
>> 
>>      I could probably find a way to do this in Matlab, but I
>>      trust the bug-squishing abilities of the freesurfer
>>      community more than I trust my own.
>> 
>>      -Clark
>> 
>>      On Aug 28, 2012, at 2:34 PM, Sebastian Moeller wrote:
>> 
>>      > Hi Clark,
>>      >
>>      >
>>      > On Aug 28, 2012, at 11:15 AM, Clark Fisher wrote:
>>      >
>>      >> Hi Bruce,
>>      >>
>>      >> Thanks.  I actually have used this function of
>>      tksurfer, but am looking for a way to save the corrected
>>      maps, so that they could be manipulated by other tools
>>      (for instance, viewed by PySurfer).
>>      >
>>      >       Does it really correct the map? I thought all it
>>      does is figure out the corrected threshold. By the way, if
>>      I understand correctly, FDR maps should be considered to
>>      be binary, that is you really do not know which voxels
>>      might be false positives, so you should not interpret all
>>      voxels to be equally significant. Having said that, almost
>>      everybody I know still looks at the p-value spatial
>>      distribution when looking at those FDR thresholded maps?
>>      (then again, I do not know any statistician...)
>>      >
>>      >
>>      > best
>>      >       Sebastian
>>      >
>>      >> I recognize that this may not be an officially
>>      supported functionality, but is there some way to save the
>>      adjusted overlays from tksurfer, or create them in some
>>      other way?
>>      >>
>>      >> Best,
>>      >> Clark
>>      >>
>>      >>
>>      >> On Aug 28, 2012, at 1:58 PM, Bruce Fischl wrote:
>>      >>
>>      >>> Hi Clark
>>      >>>
>>      >>> you shouldn't need either. Load your overlays then
>>      click the button to compute the FDR threshold in the
>>      tksurfer configure overlay interface.
>>      >>>
>>      >>> cheers
>>      >>> Bruce
>>      >>> On Tue, 28 Aug 2012, Clark Fisher wrote:
>>      >>>
>>      >>>> Ok, maybe I'm making this question too intricate.
>>      Here's the short version:
>>      >>>> How can I FDR correct painted surface significance
>>      maps when I have no talraich .xfm file and no cortical
>>      segmentation?
>>      >>>> Thanks again,
>>      >>>> Clark
>>      >>>> Hi Freesurfers,
>>      >>>> I have another monkey-specific question.  I'd like to
>>      output FDR-corrected signficance surface maps for my
>>      monkey data, or at least FDR-threshold the maps.  It seems
>>      like mri_surfcluster might be one way to go about this
>>      however:
>>      >>>>      1) I don't have any .xfm files for my monkeys,
>>      as I'm working in native space, and
>>      >>>>      2) Without segmentation, I don't have a good
>>      mask to use for the cortex only. My first attempts at
>>      work-arounds would be:
>>      >>>>      1)Try to create an identity .xfm file
>>      >>>>      2)Use the cortical ribbons from mris_volmask as
>>      a cortex mask
>>      >>>> Should these work?  If so, how should I make an
>>      identity .xfm file?  If not, is there another way to FDR
>>      correct my surface data?
>>      >>>> Thanks,
>>      >>>> Clark
>>      >>>> _______________________________________________
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>>      >
>>      > --
>>      > Sebastian Moeller
>>      >
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>>      >
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