Your FSGD file appears to have been made under windows or using an 
editor that is not simple text. The contrast matrix looks ok.

doug

On 12/01/2014 02:41 PM, lindsay hanford wrote:
> Hello Freesurfer Experts!
>
> I am encountering the dreaded mri_glmfit error:  matrix is 
> ill-conditioned or badly scaled, condno = 1e+08. I have tried to 
> troubleshoot how to solve this problem from other inquiries, however, 
> I still have had no luck. I am trying to run a 4 group 1 variable 
> analysis: with diagnosis being my variable of interest and trying to 
> regress out the effects of sex and age.
>
>   1. Command line:
>     mri_glmfit --y lh.10.73.SZHC.mgh --fsgd g4v1.73.fsgd dods --C 
> SZ-HC.intercept.73.mtx --surf fsaverage lh --cortex --glmdir g4v1.73.lh
>   2. The FSGD file (if using one) (see attached)
>   3. And the design matrix:
>            0.5 0.5 -0.5 -0.5 0 0 0 0 (or see attached)
>
> To the best of my knowledge, all my files are the right format and I 
> believe I have adequate number of participants per group?
> I also tried mean centering my age variable. I had success when I ran 
> just a two group analysis (diagnosis) not controlling for sex or age, 
> however, as soon as I try to run four groups, I encounter this error. 
> I have no idea how to proceed.
>
> I am looking forward to your response!
> Thanks,
>
>
> Lindsay
>
> -- 
> Lindsay Hanford, BSc, PhD Candidate
> McMaster Integrative Neuroscience Discovery & Study| *Department of 
> Psychology, Neuroscience & Behaviour *
> McMaster University *|* 1280 Main Street West, PC329 Psychology 
> Building *|* Hamilton, ON, L8S 4L8
> 905 525 9140 x24784***|*lindsay.hanf...@gmail.com 
> <mailto:lindsay.hanf...@gmail.com>
>
>
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-- 
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
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Fax: 617-726-7422

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